GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **263** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Receptor-type tyrosine-protein phosphatases	NT-3 growth factor receptor SLIT and NTRK like family member 1 SLIT and NTRK like family member 2	F1NEZ4 F1NZH0 Q91044	LOC121106448 NTRK3 SLITRK1 TRKC	Gallus gallus (chicken)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	BRISC and BRCA1-A complex member 2 Eyes absent homolog Eyes absent homolog Eyes absent homolog Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Polyubiquitin-B Protein inhibitor of activated STAT 4 SUMO-conjugating enzyme UBC9 Small ubiquitin-related modifier 1 Stress-activated protein kinase JNK Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein [histone H3]-trimethyl-L-lysine(9) demethylase [histone H3]-trimethyl-L-lysine(9) demethylase	A0A1D5NXI7 A0A1D5P2D1 A0A1D5P546 A0A1D5PC43 A0A1D5PGP0 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TSH5 A0A3Q2TY19 A0A3Q2UDI2 E1C6D5 F1NDD7 F1P5G5 P0C1H3 P0C1H4 P0C1H5 P0CG62 P62801 P63283 P79781 Q5ZML0 Q8QGH2 Q9PSW9	BABAM2 BRE EYA1 EYA2 EYA4 H2AFX H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L KDM4A KDM4B LOC100859381 LOC426037 MAPK8 PIAS4 RPS27A SUMO1 UBA80 UBB UBC9 UBCE9 UBE2I	Gallus gallus (chicken)
Reelin signalling pathway	DAB1, reelin adaptor protein SH3 domain-containing protein Tyrosine-protein kinase Very low-density lipoprotein receptor	A0A3Q2U639 P98165 Q5ZMQ7 Q6XBN6	DAB1 Dab1 FYN RCJMB04_1g20 VLDLR VTGR	Gallus gallus (chicken)
Regulated proteolysis of p75NTR	Nuclear factor NF-kappa-B p105 subunit Presenilin-1 Presenilin TNF receptor-associated factor Tumor necrosis factor alpha converting enzyme Tumor necrosis factor receptor superfamily member 16	E1C626 F1NGP7 P18519 Q04861 Q4JIM4 Q5QHR9	ADAM17 NFKB1 NGFR PSEN1 PSEN2 TNFRSF16 TRAF6	Gallus gallus (chicken)
Regulation of FZD by ubiquitination	Frizzled-4 Leucine rich repeat containing G protein-coupled receptor 4 Leucine rich repeat containing G protein-coupled receptor 5 Polyubiquitin-B Protein Wnt-3a R-spondin 1 R-spondin 2 Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PB24 E1BVU3 E1C2F8 I0IVW2 P0CG62 P79781 Q2LMP1 Q9IA05	FZ4 FZD4 LGR4 LGR5 RPS27A RSPO1 RSPO2 UBA80 UBB WNT3A	Gallus gallus (chicken)
Regulation of IFNA/IFNB signaling	Interferon alpha Interferon type A1/A2 Interferon type B Interferon Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 protein-tyrosine-phosphatase	A0A1I7Q402 B0FLN7 F1NMJ9 P42165 Q5ZJK3 Q90687 Q90873 Q9PWI5	IFN-gamma IFN2 IFNA IFNA1 IFNA2 IFNA3 IFNB JAK1 LOC100857947 LOC100858506 LOC100859414 LOC768614 PTPN1 PTPN11 RCJMB04_17i9	Gallus gallus (chicken)
Regulation of IFNG signaling	Interferon gamma receptor 2 (interferon gamma transducer 1) Interferon gamma Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase	A0A1D5PS87 B6RCQ2 F1NMJ9 P49708 Q5ZJK3 Q8QGH2 R4GJH9	IFNG IFNGR2 JAK1 RCJMB04_17i9 SOCS1 SOCS3 SUMO1	Gallus gallus (chicken)
Regulation of IGF Activity by IGFBP	Albumin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-L-fucosidase Amyloid beta like protein 2 Apolipoprotein A-I Beta-galactoside-binding lectin Bone morphogenetic protein 4 CCN family member 1 Cadherin-2 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Endoplasmin Fibroblast growth factor Fibronectin Insulin like growth factor binding protein 2 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor-binding protein 5 Interleukin-6 Matrilin-3 Matrix remodeling-associated protein 8 Milk fat globule EGF and factor V/VIII domain containing Ovocleidin-116 PNPLA2/ATGL Proenkephalin Reticulocalbin 1 Serine protease 23 Serpin family D member 1 Stanniocalcin-2 Sulfhydryl oxidase 1 Syndecan Uncharacterized protein	A0A1D5NW68 A0A1D5PLZ2 A0A1D5PPN9 B3TZB4 E1BRJ2 E1BS94 E1BXF4 E1C0K5 E1C0T2 E1C652 E1C744 F1ND88 F1NSM7 F1P053 F1P0A7 F1P1I0 O42401 P07583 P08250 P10288 P11722 P18254 P19336 P33717 Q5F3N4 Q5F407 Q8JGM4 Q8JIY0 Q90WI4 Q90YI0 R4GIR0 R4GLT1	ALB APLP2 APOA1 BMP4 CCN1 CDH2 CG-1B CST3 CYR61 DNAJC3 FGF23 FN1 FUCA2 HSP90B1 IGF1 IGF2 IGFBP2 IGFBP5 IL6 MATN3 MFGE8 MGAT4A MXRA8 PENK PNPLA2 PRSS23 QSCN6 QSOX QSOX1 RCJMB04_11h1 RCN1 SDC2 SERPIND1 SOX STC2	Gallus gallus (chicken)
Regulation of KIT signaling	Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Protein kinase C Proto-oncogene tyrosine-protein kinase Src SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Yes Tyrosine-protein kinase	A0A1D5PEZ2 A0A3Q2U639 A3R0S3 P00523 P09324 Q08156 Q09108 R4GHL2	FYN GRB2 KIT KITLG PRKCA SCF SOS1 SRC YES YES1	Gallus gallus (chicken)
Regulation of PLK1 Activity at G2/M Transition	14-3-3 protein epsilon Alpha-centractin Casein kinase I isoform epsilon Centrin 1 Centrosomal protein 43 Centrosomal protein 78 Centrosomal protein of 41 kDa Centrosomal protein of 63 kDa Cullin 1 Cyclin dependent kinase 1 Cytoskeleton associated protein 5 Dynein cytoplasmic 1 heavy chain 1 G2/mitotic-specific cyclin-B2 Lissencephaly-1 homolog Nuclear distribution protein nudE homolog 1 Pericentriolar material 1 protein Polyubiquitin-B Protein aurora borealis Protein phosphatase 1 regulatory subunit 12A Ras-related protein Rab-8A S-phase kinase-associated protein 1 SFI1 centrin binding protein SSNA1 protein Serine/threonine-protein kinase PLK Serine/threonine-protein phosphatase PP1-beta catalytic subunit Tubulin beta-7 chain Tubulin gamma chain Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein	A0A1D5NU82 A0A1D5P2L3 A0A1D5P546 A0A1D5PYD8 A0A3Q2U088 A0A3Q2U985 A0A3Q3ASK7 E1C065 E1C530 F1NBD7 F1NCX7 F1NKL4 F1NM71 F1NMY1 F1P288 P09244 P0CB05 P0CG62 P29332 P62207 P79781 Q5F470 Q5ZK19 Q5ZKF5 Q5ZLL1 Q5ZM58 Q5ZMC9 Q5ZMT0 Q8AV28 Q90623 Q9PTR5	ACTR1A BORA CCNB2 CDK1 CEP41 CEP63 CEP78 CETN1 CKAP5 CSNK1E CUL1 CYCB2 DBT DYNC1H1 FGFR1OP LIS1 LOC420480 MBS MYPT1 NDE1 PAFAH1B1 PCM1 PLK1 PPP1CB PPP1R12A RAB8A RCJMB04_13l14 RPS27A SFI1 SKP1 SKP1A TUBG1 UBA80 UBB YWHAE YWHAG	Gallus gallus (chicken)
Regulation of insulin secretion	ATP-sensitive inward rectifier potassium channel 11 Rap guanine nucleotide exchange factor 4 Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 cAMP-dependent protein kinase	A0A1D5PMC0 A0A3Q3AHR0 E1BZF6 F1NBC9 O73700 R4GIN8	CACNA1D CACNB2 KCNJ11 LOC107050029 PRKACB RAPGEF4	Gallus gallus (chicken)	G58161NS
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor X Osteocalcin furin	A0A1D5PRL0 P25155 Q91000	BGLAP F10 FURIN FX	Gallus gallus (chicken)
Response to elevated platelet cytosolic Ca2+	Protein kinase C Protein kinase C	A0A1D5PUY5 R4GHL2	PRKCA PRKCB	Gallus gallus (chicken)
SHC-mediated cascade:FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2TTH8 A3R0S3 E1BZW7 F1P5Y5 P08642 P19596 P21804 P48800 P48801 Q4R0X9 Q5F352 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 GRB2 HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
SHC-mediated cascade:FGFR2	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2TTH8 A3R0S3 E1BZW7 F1P5Y5 P08642 P18461 P19596 P48800 P48801 Q197G3 Q4R0X9 Q5F352 Q5KRA4 Q9I950 R4GIR0	CEK3 FGF-18 FGF-3 FGF1 FGF10 FGF18 FGF2 FGF23 FGF3 FGF4 FGF6 FGF7 FGF8 FGFR2 Fgf16 Fgf7 GRB2 HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
SHC-mediated cascade:FGFR3	Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PT95 A3R0S3 E1BZW7 P08642 P18460 P19596 P48800 Q197G3 Q4R0X9 Q5F352 Q9I950 R4GIR0	CEK2 FGF-18 FGF1 FGF18 FGF2 FGF23 FGF4 FGF8 FGFR3 Fgf16 GRB2 HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
SHC1 events in EGFR signaling	Amphiregulin Betacellulin Epigen Epiregulin GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A1D5NYP8 A0A1D5PEZ2 A0A1D5PKH0 A0A1D5PT95 A3R0S3 F1NJR9 P08642 Q5EG71 Q5F352 Q645M5 Q64EU6 Q9W7C5	AREG BTC EGFR EPGN EREG GRB2 HBEGF HEGFL HRAS HRAS1 KRAS NRAS SHC1 SOS1	Gallus gallus (chicken)
Scavenging by Class A Receptors	Apolipoprotein A-I Collectin-11 Endoplasmin	A0A1D5PPN9 A0A3Q3A736 P08250	APOA1 COLEC11 HSP90B1	Gallus gallus (chicken)	G70323CJ G82576YO
Sialic acid metabolism	Alpha-2,8-sialyltransferase Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Beta-galactoside alpha-2,6-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase Major facilitator superfamily (MFS) profile domain-containing protein N-acetylneuraminate synthase ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 exo-alpha-sialidase	A0A1D5PEI3 A0A1D5PIR8 A0A3Q2TVY6 E1BZW3 F6VMN5 P79783 Q11200 Q5ZL94 Q5ZMH8 Q6ZXD0 Q92183 R4GHQ6	NANS NEU2 RCJMB04_7b17 SIAT4A SIAT7A SIAT8C ST3GAL1 ST6GAL2 ST6GALNAC1 ST6GALNAC5 ST8SIA4 ST8SIA5 ST8SIA6 Sial-T2	Gallus gallus (chicken)
Signaling by Activin	Activin receptor type-2A Inhibin beta B chain Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Transforming growth factor beta receptor 3 receptor protein serine/threonine kinase	A0A1D5NUH3 A0A3Q2TUT8 P84023 Q8UWF3 Q90669 Q90998 R4GIS0	ACVR1C ACVR2A INHBB LOC769000 MADH2 MADH3 SMAD3 TGFBR3	Gallus gallus (chicken)
Signaling by BMP	Activin receptor type-2A Bone morphotic protein 10 Cerberus Dorsalin-1 Gremlin 2, DAN family BMP antagonist Mothers against decapentaplegic homolog 5 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Transforming growth factor beta receptor 3 receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A1D5PB14 A0A1D5PNY8 A0A3Q3AYA9 F1NTD3 F1P3H0 F6S3W4 O42124 P34822 Q56I99 Q56IA0 Q90669 Q90998 Q9PWB0	ACVR2A BMP10 BMPR1A BMPR1B BRK-3 CER1 DSL1 GREM2 MADH5 SMAD1 SMAD5 SMAD6 SMAD7 TGFBR3	Gallus gallus (chicken)
Signaling by EGFR	Amphiregulin Angio associated migratory cell protein Betacellulin Epigen Epiregulin Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src Receptor protein-tyrosine kinase	A0A1D5PKH0 F1NJR9 P00523 Q5EG71 Q5ZLQ3 Q645M5 Q64EU6 Q9W7C5	AAMP AREG BTC EGFR EPGN EREG HBEGF HEGFL SRC	Gallus gallus (chicken)
Signaling by Insulin receptor	Insulin Tyrosine-protein kinase receptor	A0A1D5P6T3 P67970	INS INSR	Gallus gallus (chicken)
Signaling by PDGF	Collagen type IV alpha 1 chain Plasminogen activator Plasminogen Platelet-derived growth factor C Platelet-derived growth factor D Platelet-derived growth factor subunit A Thrombospondin 4 furin	A0A1D5P8P3 A0A3Q2U6E1 E1C209 F1NBP0 F1NWX6 Q90WK2 Q91000 Q9I946	COL4A1 FURIN PDGF-A (L) PDGFA PDGFC PDGFD PLAT PLG SCDGF THBS4	Gallus gallus (chicken)
Signaling by SCF-KIT	GRB2 related adaptor protein 2 GTPase HRas GTPase NRas Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Kit ligand Mast/stem cell growth factor receptor Kit Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Protein kinase C Proto-oncogene tyrosine-protein kinase Src SOS Ras/Rac guanine nucleotide exchange factor 1 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Tyrosine-protein kinase Yes Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 11 small monomeric GTPase	A0A1D5P405 A0A1D5PEZ2 A0A1D5PT95 A0A3Q2U639 A0A3Q3ACS4 A3R0S3 E1BQF3 E1C2C5 E1C7Z1 F1NZY8 P00523 P08642 P09324 Q08156 Q09108 Q5F352 Q5ZJK3 Q6DV79 Q90687 R4GHL2	FER FYN GRAP2 GRB10 GRB2 HRAS HRAS1 KIT KITLG KRAS NRAS PIK3R1 PIK3R2 PRKCA PTPN11 RCJMB04_17i9 SCF SOS1 SRC STAT3 TEC YES YES1	Gallus gallus (chicken)

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