GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **201 - 225** of **263** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
FGFR1b ligand binding and activation	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Transforming growth factor beta receptor 3	A0A3Q2TTH8 P19596 P21804 P48800 P48801 Q90998	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF3 FGFR1 TGFBR3	Gallus gallus (chicken)
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor X	P25155	F10 FX	Gallus gallus (chicken)
Extra-nuclear estrogen signaling	72 kDa type IV collagenase Amphiregulin Betacellulin Caveolin Epigen Epiregulin Focal adhesion kinase 1 G protein subunit alpha transducin 3 G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Matrix metallopeptidase 10 Palmitoyltransferase Palmitoyltransferase Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase Src RAC-alpha serine/threonine-protein kinase Receptor protein-tyrosine kinase SHC-transforming protein 1 Sphingosine kinase 1	A0A1D5NVK1 A0A1D5NYP8 A0A1D5P1F1 A0A1D5P7Z5 A0A1D5PKH0 A0A1D5PLZ8 A0A3Q2U4X3 A0A3Q3ACS4 A0M8T8 E1BW98 E1BXS2 E1C1U6 E1C2C5 E1C795 E1C9E0 F1NJR9 F1NLV4 F1P3R0 P00523 P50147 Q00944 Q5EG71 Q5F3P6 Q5ZJ03 Q645M5 Q64EU6 Q90611 Q90847 Q9W7C5 R4GFT9 R4GKD1	AKT1 AREG BTC CAV1 EGFR EPGN EREG FAK FAK1 GNAI1 GNAI2 GNAI3 GNAT3 GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 Galphai3 HBEGF HEGFL MMP10 MMP2 PIK3R1 PIK3R2 PTK2 SHC1 SPHK1 SRC ZDHHC21 ZDHHC7	Gallus gallus (chicken)
Estrogen-dependent gene expression	Core-binding factor beta subunit DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Forkhead box A1 GATA-binding factor 3 General transcription facter IIA subunit 1 variant 1 Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Histone deacetylase 1 Nuclear receptor coactivator Nuclear receptor interacting protein 1 Nuclear receptor subfamily 5 group A member 2 Probable ATP-dependent RNA helicase DDX5 Protein c-Fos RNA polymerase II subunit C Runt-related transcription factor TATA-box-binding protein TLE family member 3, transcriptional corepressor Transcription initiation factor IIA subunit 2 YY2 transcription factor [histone H3]-trimethyl-L-lysine(9) demethylase peptidylprolyl isomerase	A0A1D5PCB1 A0A1D5PUH1 A0A1D5PY49 A0A1L1RNY8 A0A3Q2TSH5 A0A3Q2TTQ9 A0A3Q2U9P1 A0A3Q2UDI2 A0A3S5ZPN3 A1IIE5 A1IIE6 E1BSY6 E1BV97 F1NCB0 F1NDB6 F1NDD7 F1NHV6 F1NHV9 F1NQP4 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P11939 P23825 P56517 P62801 P70082 P84229 P84247 Q5F393 Q6JLB1 Q9PSW9 Q9PT88 R4GIS3	CBFB DDX5 FKBP4 FOS FOXA1 GATA3 GTF2A1 GTF2A2 H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HDAC1 HDAC1A HIST1H2B5L KDM4B LOC100859381 LOC426037 NCOA1 NR5A2 NRIP1 POLR2B POLR2C POLR2E POLR2L RPB6 RUNX1 TBP TLE3 YY2	Gallus gallus (chicken)
Electric Transmission Across Gap Junctions	Gap junction gamma-1 protein Gap junction protein Pannexin	A0A1D5P0I0 P18861 Q8UVE3	GJA7 GJC1 GJD2 PANX PANX1	Gallus gallus (chicken)
Effects of PIP2 hydrolysis	Diacylglycerol kinase Diacylglycerol kinase Inositol 1,4,5-trisphosphate receptor Protein kinase C delta type Protein kinase C Transient receptor potential cation channel subfamily C member 7	A0A1D5PLX8 F1NDU2 F1NJH1 F1NYQ1 F1P1X4 F1P3G1	DGKB DGKK ITPR2 PRKCD PRKCH TRPC7	Gallus gallus (chicken)
ESR-mediated signaling	peptidylprolyl isomerase peptidylprolyl isomerase	A0A3Q2U9P1 Q646T7	FKBP4 FKBP5 FKBP51	Gallus gallus (chicken)
EPH-Ephrin signaling	Ephrin A2 Ephrin type-A receptor 4 Ephrin type-A receptor 7 Ephrin-B1 Ephrin-B2 receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A1D5NZN5 A0A1D5P9X0 F1NJX6 F1NSE6 O42422 Q07496 Q9PUJ4	CEK11 CEK8 EFNA2 EFNB1 EFNB2 EPHA3 EPHA4 EPHA5 EPHA7	Gallus gallus (chicken)
EGFR interacts with phospholipase C-gamma	Amphiregulin Betacellulin Epigen Epiregulin Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase	A0A1D5PKH0 F1NJR9 Q5EG71 Q645M5 Q64EU6 Q9W7C5	AREG BTC EGFR EPGN EREG HBEGF HEGFL	Gallus gallus (chicken)
EGFR downregulation	Amphiregulin Betacellulin Cell division control protein 42 homolog Endophilin-A1 Epigen Epiregulin Growth factor receptor-bound protein 2 Polyubiquitin-B Proheparin-binding EGF-like growth factor Protein sprouty homolog 1 Receptor protein-tyrosine kinase Rho guanine nucleotide exchange factor 7 SH3 domain containing GRB2 like 3, endophilin A3 SH3 domain-containing protein Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PKH0 A0A3Q2TZR1 A3R0S3 A4LA71 F1NB17 F1NJR9 P0CG62 P79781 Q5EG71 Q5ZMQ7 Q645M5 Q64EU6 Q8AXV1 Q90694 Q9W7C5	AREG ARHGEF7 BTC CDC42 EGFR EPGN EREG GRB2 HBEGF HEGFL RCJMB04_1g20 RPS27A SH3GL2 SH3GL3 SH3P4 SPRY1 UBA80 UBB	Gallus gallus (chicken)
ECM proteoglycans	Decorin Hyaluronan and proteoglycan link protein 1 Integrin beta Integrin subunit alpha 9 Matrilin-3	A0A1D5PQP8 A0A1L1RX77 O42401 P07354 Q92071	CRTL1 DCN HAPLN1 ITGA9 ITGB3 MATN3	Gallus gallus (chicken)
Downstream signaling of activated FGFR1	Fibroblast growth factor 10 Fibroblast growth factor 1 Fibroblast growth factor 2 Fibroblast growth factor 3 Fibroblast growth factor receptor 1 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine rich transmembrane protein 2 Leucine-rich repeat transmembrane protein FLRT3	A0A3Q2TTH8 E1BZW7 E1C6W5 F1NUK7 F1P5Y5 P19596 P21804 P48800 P48801 Q4R0X9 R4GIR0	CEK1 FGF-3 FGF1 FGF10 FGF2 FGF23 FGF3 FGF4 FGF6 FGF8 FGFR1 FLRT2 FLRT3	Gallus gallus (chicken)
Downregulation of TGF-beta receptor signaling	BMP and activin membrane-bound inhibitor homolog E3 ubiquitin-protein ligase CHIP Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-B Prostate transmembrane protein, androgen induced 1 Serine-threonine kinase receptor-associated protein TGF-beta receptor type-1 TGF-beta receptor type-2 Transforming growth factor beta Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5NUH3 A0A1D5P546 A0A1D5PNY8 E1AWU3 H9CX01 P0CG62 P79781 P84023 Q06900 Q5ZHY5 Q5ZJ16 Q5ZL33 Q8UWF3 Q90999	BAMBI ChALK5 LOC769000 MADH2 MADH3 PMEPA1 RPS27A SMAD3 SMAD7 STRAP STUB1 TGFB1 TGFBR1 TGFBR2 UBA80 UBB	Gallus gallus (chicken)
Downregulation of SMAD2/3:SMAD4 transcriptional activity	Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-B Protein ATP1B4 SKI like proto-onco Ski oncogene Ubiquitin B Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5NUH3 A0A1D5P546 E1BSJ7 F1P0N0 P0CG62 P79781 P84023 Q2HZ96 Q8UWF3	ATP1B4 LOC769000 MADH2 MADH3 RPS27A SKI SKIL SMAD3 UBA80 UBB	Gallus gallus (chicken)
Disassembly of the destruction complex and recruitment of AXIN to the membrane	Axin-1 Caveolin Protein Wnt-3a Protein Wnt	A0A1D5P395 A0M8T8 Q2LMP1 Q564K5	AXIN1 CAV1 WNT3A Wnt8c	Gallus gallus (chicken)
Digestion of dietary carbohydrate				Gallus gallus (chicken)	G58161NS G74621DY G93924TT G96370VA
Digestion	Guanylate cyclase activator 2B Guanylate cyclase	E1BZE2 R4GIC2	GUCA2B GUCY2C	Gallus gallus (chicken)
Deposition of new CENPA-containing nucleosomes at the centromere	Centromere protein H Centromere protein I Centromere protein L Centromere protein M Centromere protein N Centromere protein O Centromere protein S Centromere protein T Centromere protein W Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 Opa interacting protein 5 Protein Mis18-alpha RB binding protein 4, chromatin remodeling factor RuvB-like helicase	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1BQA1 E1BQA3 E1BSW7 F1N8S4 F1N8Z4 F1NDD7 F1NPG5 F1P5G5 F2Z4M0 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P0DJH6 P62801 P70082 Q1T765 Q1T7B9 Q1T7C0 Q8AYS7 Q90ZF9 Q9PSW9	APITD1 CENPH CENPI CENPL CENPM CENPN CENPO CENPS CENPT CENPW H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 MIS18A OIP5 RBBP4 RUVBL1	Gallus gallus (chicken)
Degradation of the extracellular matrix	72 kDa type IV collagenase ADAM metallopeptidase with thrombospondin type 1 motif 5 Basigin Cathepsin V Decorin Disintegrin and metalloproteinase domain-containing protein 10 Matrix metallopeptidase 10 interstitial collagenase	A0A1L1RX77 E1C9D9 E1C9E0 F1NYJ1 F1P3S7 P17790 Q5F3N4 Q90611	ADAMTS5 BSG CTSV DCN MMP1 MMP10 MMP2 RCJMB04_11h1	Gallus gallus (chicken)
Dectin-2 family	Hepatic lectin	P02707		Gallus gallus (chicken)
Cross-presentation of soluble exogenous antigens (endosomes)	Hepatic lectin	P02707		Gallus gallus (chicken)
Creation of classical C3 convertase	Complement 4 Complement C1q B chain Complement C1q subcomponent subunit A Complement C1s subcomponent Complement factor B-like protease (Fragment) Ig lambda chain C region Ig lambda chain V-1 region Ig mu chain C region MAp19 MHC-linked complement C4 Mannan-binding lectin associated serine protease 2 Mannan-binding lectin associated serine protease 3 Mannose-binding protein VH1 protein (Fragment) complement subcomponent C1r	A0A3Q2UG72 A0A8V0Z078 A2N884 F1NAB7 F1NH19 P01875 P04210 P20763 P81475 Q076D6 Q5F3N3 Q6Q1Q7 Q6Q1Q8 Q6Q1Q9 Q98TA4	C1QA C1QB C1R C4 C4-2 MASP2 MBL RCJMB04_11h6 VH1	Gallus gallus (chicken)
Condensation of Prophase Chromosomes	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H4 RB transcriptional corepressor 1 Serine/threonine-protein kinase PLK	A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 A0A3Q3AS57 F1NCX7 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 PLK1 RB1	Gallus gallus (chicken)
Complement Cascade	Complement 4 Complement C3 Complement C5 Complement factor B-like protease (Fragment) Complement regulatory GPI-anchor protein Complement regulatory membrane protein MHC-linked complement C4	A0A3Q2UG72 A0A8V1AM71 P81475 Q076D6 Q4AEI5 Q90633 Q9DEG0	C4 C4-2 C5 CREG Cremp	Gallus gallus (chicken)
Common Pathway of Fibrin Clot Formation	Coagulation factor X Coagulation factor XIII A chain Endothelial protein C receptor Serpin family D member 1 Serpin family E member 2	A0A1D5PLZ2 E1BWG1 E1BWU2 P25155 Q4ADW2	F10 F13A1 FX PROCR SERPIND1 SERPINE2	Gallus gallus (chicken)

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