GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **263** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID ▼
Galactose catabolism	Phosphoglucomutase-1	F1NN63	PGM1	Gallus gallus (chicken)	G93924TT
Lewis blood group biosynthesis	Alpha-(1,3)-fucosyltransferase Fucosyltransferase Fucosyltransferase Hexosyltransferase Hexosyltransferase	E1BZG7 E1C2U3 E1C4T5 Q8UWB9 Q8UWC1	B3GALT1 B3GALT5 CFTII FUT10 FUT7 FUT9 cFuc-TIX	Gallus gallus (chicken)	G90387AM
N-Glycan antennae elongation	Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-2,8-sialyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase MGAT4 family member C ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase	A0A1D5PEI3 A0A1D5PSH8 A0A3S5ZPV4 F1NEL5 Q5F407 Q6ZXD0 R4GKF3	B4GALT2 B4GALT6 LOC427873 MGAT4A MGAT5 SIAT8C ST8SIA6	Gallus gallus (chicken)	G81533KY
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase	F1P0Z9	MAN1C1	Gallus gallus (chicken)	G70323CJ
Reactions specific to the complex N-glycan synthesis pathway				Gallus gallus (chicken)	G70323CJ G82576YO
Scavenging by Class A Receptors	Apolipoprotein A-I Collectin-11 Endoplasmin	A0A1D5PPN9 A0A3Q3A736 P08250	APOA1 COLEC11 HSP90B1	Gallus gallus (chicken)	G70323CJ G82576YO
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl peptidase 4 G protein subunit alpha transducin 3 G protein subunit beta 3 G protein subunit gamma 13 G protein-coupled receptor 119 Gastrin-releasing peptide Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Pro-glucagon	A0A1D5P7Z5 A0A1D5PJA5 E1C1U6 F1NLV4 F1P3R0 M9NJI3 P01295 P68259	DPP4 GCG GNAT3 GNB1 GNB3 GNG13 GPR119 GRP	Gallus gallus (chicken)	G58161NS
Glycogen breakdown (glycogenolysis)	Phosphoglucomutase-1 glycogenin glucosyltransferase	A0A1D5PAA8 F1NN63	GYG1 PGM1	Gallus gallus (chicken)	G58161NS
Glucose transport	Hexokinase-1 Hexokinase-2 Phosphotransferase (Fragment) Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 3	P28568 P46896 Q8AYP7 Q8AYP8 Q8JHA6 Q90592	GLUT1 GLUT2 GLUT3 HK1 HK2 SLC2A1 SLC2A2 SLC2A3	Gallus gallus (chicken)	G58161NS
Regulation of insulin secretion	ATP-sensitive inward rectifier potassium channel 11 Rap guanine nucleotide exchange factor 4 Voltage-dependent L-type calcium channel subunit alpha-1D Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 cAMP-dependent protein kinase	A0A1D5PMC0 A0A3Q3AHR0 E1BZF6 F1NBC9 O73700 R4GIN8	CACNA1D CACNB2 KCNJ11 LOC107050029 PRKACB RAPGEF4	Gallus gallus (chicken)	G58161NS
Fructose biosynthesis	Sorbitol dehydrogenase	P0DMQ6	SORD	Gallus gallus (chicken)	G58161NS
Glycolysis	ATP-dependent 6-phosphofructokinase Enolase 4 Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase Glucosamine-6-phosphate isomerase Glucosamine-6-phosphate isomerase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoglucomutase 2 like 1 Phosphoglycerate mutase 1 Phosphoglycerate mutase Pyruvate kinase PKM Triosephosphate isomerase phosphopyruvate hydratase	A0A1L1RQ91 A0A1L1RRN7 A0A3Q3AEZ3 E1C878 F1NAA5 F1NKB6 P00356 P00548 P00940 P07341 Q5ZHV4 Q5ZLA0 Q5ZLN1 R4GM10	ALDOB ALDOC ENO2 ENO4 GAPD GAPDH GNPDA1 GNPDA2 GPI PFKL PGAM1 PGM2L1 PKM RCJMB04_32o10 TPI1	Gallus gallus (chicken)	G58161NS
Synthesis, secretion, and deacylation of Ghrelin	Appetite-regulating hormone Insulin-like growth factor I Insulin Pro-glucagon Signal peptidase complex catalytic subunit SEC11 Signal peptidase complex subunit 3 Somatotropin	P08998 P18254 P28687 P67970 P68259 Q5ZMQ3 Q8AV73	GCG GH GHRL IGF1 INS SEC11A SPC22 SPCS3 ghr ghre	Gallus gallus (chicken)	G58161NS
N-glycan trimming and elongation in the cis-Golgi				Gallus gallus (chicken)	G58161NS
Gluconeogenesis	Enolase 4 Fructose-bisphosphate aldolase B Fructose-bisphosphate aldolase Glucose-6-phosphatase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoenolpyruvate carboxykinase, cytosolic [GTP] Phosphoglycerate mutase 1 Solute carrier family 37 member 4 Triosephosphate isomerase phosphopyruvate hydratase	A0A1L1RQ91 A0A1L1RRN7 A0A3Q3AEZ3 F1NKP4 F1NTA5 F1NTH9 P00356 P00940 P07341 Q5ZLN1 R4GM10	ALDOB ALDOC ENO2 ENO4 G6PC2 GAPD GAPDH GPI PCK1 PGAM1 SLC37A4 TPI1	Gallus gallus (chicken)	G58161NS
Intestinal hexose absorption	Solute carrier family 2 member 5	F1NVV4	SLC2A5	Gallus gallus (chicken)	G58161NS G93924TT
Lactose synthesis	Lysozyme C	P00698	LYZ	Gallus gallus (chicken)	G58161NS G74621DY
Digestion of dietary carbohydrate				Gallus gallus (chicken)	G58161NS G74621DY G93924TT G96370VA
Cellular hexose transport	Solute carrier family 2 member 11 Solute carrier family 2 member 5 Solute carrier family 2 member 8 Solute carrier family 2, facilitated glucose transporter member 12 Solute carrier family 2, facilitated glucose transporter member 3	E1C4E5 F1NDA6 F1NTJ1 F1NVV4 F1P4J7	SLC2A11 SLC2A12 SLC2A14 SLC2A5 SLC2A8	Gallus gallus (chicken)	G58161NS G70323CJ
Antimicrobial peptides	Angiogenin Cathelicidin B1 Cathelicidin-1 Cathelicidin-2 Cathelicidin-3 Chromogranin-A Liver ribonuclease A Lysozyme C NK-lysin Ribonuclease homolog	F1NLZ2 P00698 P27043 P30374 Q2I811 Q2IAL6 Q2IAL7 Q5GAL6 Q6QLQ5 R4GJF1	ANG CATH CATHB1 CATHL1 CATHL2 CATHL3 CHGA CL2 CMAP27 GNLY LYZ	Gallus gallus (chicken)	G49108TO
Initial triggering of complement	Collectin-10 Collectin-11 Complement C1q B chain Complement C1q C chain Mannose-binding protein Uncharacterized protein complement subcomponent C1r	A0A1D5PGB2 A0A1D5PIR0 A0A3Q3A736 F1NAB7 F1NH19 Q2LK95 Q98TA4	C1QB C1QC C1R CL1 COLEC10 COLEC11 MBL	Gallus gallus (chicken)	G49108TO G57321FI
Ficolins bind to repetitive carbohydrate structures on the target cell surface				Gallus gallus (chicken)	G49108TO G57321FI
Lectin pathway of complement activation	Collectin-10 Collectin-11 Mannose-binding protein	A0A3Q3A736 Q2LK95 Q98TA4	CL1 COLEC10 COLEC11 MBL	Gallus gallus (chicken)	G49108TO G57321FI
Hyaluronan uptake and degradation	Beta-hexosaminidase Calcineurin B homologous protein 1 Glucuronidase beta Lymphatic vessel endothelial hyaluronan receptor 1	A0A1L1RSD2 E1C9I1 F1NTQ2 Q5ZM44	CHP CHP1 GUSB HEXB LYVE1	Gallus gallus (chicken)	G35674CY
Hyaluronan biosynthesis and export	Hyaluronan synthase 3	O57425	HAS3	Gallus gallus (chicken)	G35674CY

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