GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **263** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
A tetrasaccharide linker sequence is required for GAG synthesis	Beta-1,4-galactosyltransferase Decorin Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Glypican-1 Syndecan-4 Syndecan Syndecan Xylosyltransferase 2	A0A1D5P9Q8 A0A1L1RX77 F1NU53 F1NV24 F1P150 P49416 Q2HPN7 Q8JIY0	B3GAT2 B4GAL-T7 DCN GPC1 SDC1 SDC2 SDC4 XYLT2	Gallus gallus (chicken)
ADP signalling through P2Y purinoceptor 1	Cytosolic phospholipase A2 G protein subunit beta 3 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma P2Y purinoceptor 1 Proto-oncogene tyrosine-protein kinase Src mitogen-activated protein kinase	A0A1D5P7Z5 A0A1D5PIQ5 A0A1D5PLZ8 E1BW98 E1C1U6 E1C795 F1NLV4 P00523 P34996 P49147 Q5F3B5 Q5ZJ03 Q71RI7 R4GFT9 R4GKD1	CPLA2 GNA11 GNAQ GNB1 GNB3 GNB4 GNG10 GNG12 GNG13 GNG2 GNG5 GNGT2 MAPK14 P2RY1 PLA2G4 PLA2G4A SRC	Gallus gallus (chicken)
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin-1 Solute carrier family 5 member 7 Synaptosomal-associated protein 25 Synaptotagmin-1 Syntaxin-binding protein 1 Unc-13 homolog B	A0A1D5PHU2 E1C8G7 F1NY18 F1P393 F1P4Q0 P47191 P60878	CHAT CPLX1 SLC5A7 SNAP SNAP25 STXBP1 SYT1 UNC13B	Gallus gallus (chicken)
Activated NTRK2 signals through FRS2 and FRS3	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor Fibroblast growth factor receptor substrate 2 Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A1D5PEZ2 A3R0S3 E1C021 P25429 Q91987	BDNF FRS2 GRB2 NTRK2 SOS1 TRKB	Gallus gallus (chicken)
Activated NTRK2 signals through PLCG1	BDNF/NT-3 growth factors receptor Brain-derived neurotrophic factor	P25429 Q91987	BDNF NTRK2 TRKB	Gallus gallus (chicken)
Activated NTRK3 signals through PI3K	NT-3 growth factor receptor Neurotrophin-3 Proto-oncogene tyrosine-protein kinase Src	A0A3Q2U804 P00523 Q91044	NTF3 NTRK3 SRC TRKC	Gallus gallus (chicken)
Activated NTRK3 signals through PLCG1	NT-3 growth factor receptor Neurotrophin-3	A0A3Q2U804 Q91044	NTF3 NTRK3 TRKC	Gallus gallus (chicken)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	Androgen receptor Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4	A0A1D5P088 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDD7 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 P84247 Q9PSW9	AR H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037	Gallus gallus (chicken)
Activation of the phototransduction cascade	Cyclic nucleotide-gated channel rod photoreceptor subunit alpha Rhodopsin	F1P3Y2 Q90980	RHO	Gallus gallus (chicken)
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2b	O13076 P49892	ADORA1 ADORA2B	Gallus gallus (chicken)
Adherens junctions interactions	Angiogenin Cadherin 18 Cadherin 7 Cadherin domain-containing protein Cadherin-13 Cadherin-2 Cadherin-5 Cadherin-6 Catenin beta-1 Catenin delta 1 Junction plakoglobin Liver ribonuclease A Nectin cell adhesion molecule 3 Ribonuclease homolog	A0A1D5NYE8 A0A1D5PKP1 A0A3Q2U1A5 E1C1V3 E1C235 F1NKK8 F1P1D4 P10288 P27043 P30374 P33150 Q5GAL6 Q8AYD0 Q90762	ANG CDH12 CDH13 CDH18 CDH2 CDH5 CDH6 CDH7 CL2 CTNNB1 CTNND1 JUP NECTIN3	Gallus gallus (chicken)
Antimicrobial peptides	Angiogenin Cathelicidin B1 Cathelicidin-1 Cathelicidin-2 Cathelicidin-3 Chromogranin-A Liver ribonuclease A Lysozyme C NK-lysin Ribonuclease homolog	F1NLZ2 P00698 P27043 P30374 Q2I811 Q2IAL6 Q2IAL7 Q5GAL6 Q6QLQ5 R4GJF1	ANG CATH CATHB1 CATHL1 CATHL2 CATHL3 CHGA CL2 CMAP27 GNLY LYZ	Gallus gallus (chicken)	G49108TO
Arachidonate production from DAG	Abhydrolase domain containing 6, acylglycerol lipase Lysophosphatidylserine lipase ABHD12	E1C7P7 Q5ZIN0	ABHD12 ABHD6	Gallus gallus (chicken)
Arachidonic acid metabolism	Cytosolic phospholipase A2	P49147	CPLA2 PLA2G4 PLA2G4A	Gallus gallus (chicken)
Asparagine N-linked glycosylation	Hepatic lectin	P02707		Gallus gallus (chicken)
Aspirin ADME	ABC-type glutathione-S-conjugate transporter Albumin Basigin Cytochrome P450 CYP2D49 Monocarboxylate transporter 1	A0A1D5NW68 F1NJG4 F1NM51 P17790 Q5ZLZ6	ABCC3 ALB BSG CYP2D6 RCJMB04_4e8	Gallus gallus (chicken)
Assembly of active LPL and LIPC lipase complexes	Lipoprotein lipase Uncharacterized protein furin	A0A1L1RJC1 P11602 Q91000	FURIN LOC101747868 LPL	Gallus gallus (chicken)
Assembly of the ORC complex at the origin of replication	Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Importin subunit alpha Karyopherin subunit beta 1	A0A1D5P1W7 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 F1NDD7 F1P5G5 F7B5S0 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P62801 P70082 P84229 P84247 Q9PSW9	H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L KPNA6 KPNB1 LOC100859381 LOC426037	Gallus gallus (chicken)
Assembly of the pre-replicative complex	26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 2 26S proteasome regulatory subunit 7 AAA+ ATPase domain-containing protein Anaphase-promoting complex subunit CDC26 Cell division cycle protein 27 homolog DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM5 DNA replication licensing factor MCM6 Fizzy/cell division cycle 20 related 1 Polyubiquitin-B Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Ubiquitin B Ubiquitin-conjugating enzyme E2 C Ubiquitin-ribosomal protein eS31 fusion protein	A0A1D5P546 A0A1D5PJW4 A0A3Q2UD09 E1BX02 E1C2U4 E1C6N0 F1NC02 F1NEQ6 F1NFJ0 F1NPQ0 F1NR71 H9L1Y1 P0CG62 P79781 P84169 Q5F3J5 Q5ZIT7 Q5ZJL3 Q5ZJX9 Q5ZK91 Q5ZKL0 Q5ZKR8 Q5ZLI2 Q5ZMB8 Q6JLB2 Q7ZT63 R4GJY8 R4GLB3	CDC26 FZR1 MCM3 MCM4 MCM5 PSMA3 PSMA4 PSMA6 PSMA7 PSMB1 PSMB2 PSMB7 PSMC2 PSMD12 PSMD13 PSMD14 PSMD2 PSMD7 PSME3 PSMF1 RCJMB04_12e16 RCJMB04_14i9 RCJMB04_23k2 RCJMB04_9i8 RPS27A UBA80 UBB UBE2U cpsmb7	Gallus gallus (chicken)
Axonal growth stimulation	GTP-binding protein Rho GDP-dissociation inhibitor 1 Tumor necrosis factor receptor superfamily member 16	F1P3P3 O93467 P18519	ARHGDIA NGFR RHOA TNFRSF16 cRhoA rhoA	Gallus gallus (chicken)
B-WICH complex positively regulates rRNA expression	Actin, cytoplasmic 1 DEK proto-onco DNA-directed RNA polymerase II subunit E DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Histone H2A-IV Histone H2A.J Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2/3/4/6 Histone H2B 5 Histone H2B 7 Histone H2B 8 Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Splicing factor 3b subunit 1 TATA box-binding protein-associated factor RNA polymerase I subunit B TATA-box-binding protein	A0A1D5PW04 A0A1D5PY49 A0A1L1RNY8 A0A3Q2UDI2 E1BSY6 E1C2C3 F1NDD7 F1NHV9 F1P5G5 P02263 P02272 P0C1H3 P0C1H4 P0C1H5 P60706 P62801 P70082 P84229 P84247 Q5F422 Q5ZJR9 Q6JLB1 Q9PSW9 Q9PT88	ACTB DEK H2A-IX H2AF H2AFX H2AZ2 H2B-I H2B-II H2B-III H2B-IV H2B-V H2B-VI H2B-VII H2B-VIII H3-I H3-II H3-III H3-IV H3-IX H3-V H3-VI H3-VII H3-VIII H3-X H4-I H4-II H4-III H4-IV H4-V H4-VI H4-VII HIST1H2B5L LOC100859381 LOC426037 POLR1B POLR2E POLR2L RPB6 SF3B1 TAF1B TBP	Gallus gallus (chicken)
Basigin interactions	Basigin Caveolin Integrin alpha-6 Monocarboxylate transporter 1 Sodium/potassium-transporting ATPase subunit beta-3 interstitial collagenase	A0M8T8 E1C9D9 P17790 P26007 P33879 Q5ZLZ6	ATP1B3 BSG CAV1 ITGA6 MMP1 RCJMB04_4e8	Gallus gallus (chicken)
Biosynthesis of DHA-derived SPMs	Prostaglandin G/H synthase 2	P27607	CEF-147 PTGS2	Gallus gallus (chicken)
Biosynthesis of DPAn-3 SPMs	Prostaglandin G/H synthase 2	P27607	CEF-147 PTGS2	Gallus gallus (chicken)
Biosynthesis of EPA-derived SPMs	Prostaglandin G/H synthase 2	P27607	CEF-147 PTGS2	Gallus gallus (chicken)

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