GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **250** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Ciprofloxacin ADME	Probable ATP-dependent permease	P25371	ADP1	Saccharomyces cerevisiae (brewer's yeast)
HDACs deacetylate histones	Chromatin assembly factor 1 subunit p50 Histone H2A.1 Histone H2A.2 Histone H2B.1 Histone H2B.2 Histone H3-like centromeric protein CSE4 Histone H4 Histone acetyltransferase type B subunit 2 Histone deacetylase HDA1 Histone deacetylase HOS1 Histone deacetylase RPD3 Probable DNA-binding protein SNT1 Probable histone deacetylase HOS2 SIR4-interacting protein SIF2 SWI/SNF chromatin-remodeling complex subunit SWI1 Transcriptional modulator WTM1 Transcriptional modulator WTM2 Transcriptional regulatory protein DEP1 Transcriptional regulatory protein SAP30 Transcriptional regulatory protein SDS3 Transcriptional regulatory protein UME1	P02293 P02294 P02309 P04911 P04912 P09547 P13712 P25357 P31385 P32561 P36012 P38262 P38429 P39984 P40505 P53096 P53973 Q03010 Q12206 Q12214 Q12363	ADR6 CAC3 CSE4 CSL2 DEP1 EMB1 FUN54 GAM3 H2A1 H2A2 H2B1 H2B2 HAT2 HDA1 HHF1 HHF2 HOS1 HOS2 HTA1 HTA2 HTB1 HTB2 MOF6 MSI1 REC3 RPD3 SAP30 SDI2 SDS3 SDS6 SIF2 SNT1 SPT11 SPT12 SWI1 UME1 WTM1 WTM2 WTM3	Saccharomyces cerevisiae (brewer's yeast)
Platelet degranulation	Actin-interacting protein 1 Actin-like protein ARP9 Hsp90 co-chaperone Cdc37 NADH-cytochrome b5 reductase 1 Non-structural maintenance of chromosome element 3 NuA3 HAT complex component NTO1 Obg-like ATPase 1 Plasma membrane-associated coenzyme Q6 reductase PGA3 Protein AFR1 Protein BNI4 Protein transport protein SEC1 Superoxide dismutase [Cu-Zn] Suppressor protein STM1 Transgelin Tubulin alpha-1 chain Tubulin alpha-3 chain Uncharacterized oxidoreductase AIM33 Uncharacterized protein YER158C t-SNARE VTI1	P00445 P06101 P09733 P09734 P30619 P33304 P38219 P38626 P39015 P40095 P46680 P53858 Q04338 Q04516 Q05123 Q05541 Q08873 Q12311 Q12746	AFR1 AIM33 AIP1 ARP9 BNI4 CBR CBR1 CBR5 CDC37 MPT4 NQR1 NSE3 NTO1 OLA1 PGA3 SCP1 SEC1 SMO1 SOD1 STM1 STO1 SWP59 TUB1 TUB3 VTI1 YER158C	Saccharomyces cerevisiae (brewer's yeast)
Detoxification of Reactive Oxygen Species	Cytochrome c isoform 1 Cytochrome c isoform 2 Glutathione reductase Peroxiredoxin AHP1 Peroxiredoxin TSA1 Peroxiredoxin TSA2 Peroxisomal catalase A Probable ferric reductase transmembrane component 8 Probable metalloreductase AIM14 Superoxide dismutase 1 copper chaperone Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Thioredoxin-1 Thioredoxin-2 Thioredoxin-3, mitochondrial	P00044 P00045 P00445 P00447 P15202 P22217 P22803 P25372 P34760 P38013 P40202 P41921 P53109 Q04120 Q12209	AHP1 AIM14 CCS1 CTA1 CYC1 CYC7 CYP3 FRE8 GLR1 LYS7 SOD1 SOD2 TPX1 TRX1 TRX2 TRX3 TSA TSA1 TSA2 ZRG14	Saccharomyces cerevisiae (brewer's yeast)
TP53 Regulates Metabolic Genes	Glucose-6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glutathione reductase Peroxiredoxin AHP1 Peroxiredoxin TSA1 Peroxiredoxin TSA2 Thioredoxin-1 Thioredoxin-2 Thioredoxin-3, mitochondrial	P11412 P12709 P22217 P22803 P25372 P34760 P38013 P41921 Q04120	AHP1 GLR1 MET19 PGI1 TPX1 TRX1 TRX2 TRX3 TSA TSA1 TSA2 ZRG14 ZWF1	Saccharomyces cerevisiae (brewer's yeast)
Thyroxine biosynthesis	Probable ferric reductase transmembrane component 8 Probable metalloreductase AIM14	P53109 Q12209	AIM14 FRE8	Saccharomyces cerevisiae (brewer's yeast)
RA biosynthesis pathway	Aldehyde dehydrogenase 5, mitochondrial D-arabinose dehydrogenase [NAD(P)+] heavy chain Magnesium-activated aldehyde dehydrogenase, cytosolic NADPH-dependent alpha-keto amide reductase Oxidoreductase-like protein SRL4 Potassium-activated aldehyde dehydrogenase, mitochondrial Probable oxidoreductase ENV9 S-(hydroxymethyl)glutathione dehydrogenase Uncharacterized oxidoreductase TDA5 Uncharacterized oxidoreductase YDL114W Uncharacterized oxidoreductase YJR096W Uncharacterized oxidoreductase YKL107W Uncharacterized oxidoreductase YNL181W	P32771 P34251 P38115 P40047 P46367 P47137 P53878 P54115 Q03085 Q06417 Q07530 Q07551 Q08651	ALD3 ALD4 ALD5 ALD6 ALD7 ALDH1 ALDH2 ALDH5 ARA1 ENV9 SFA SFA1 SRL4 TDA5 YDL114W YDL124W YJR096W YKL107W YNL181W	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodelling of PS	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Lysophospholipid acyltransferase Oxysterol-binding protein homolog 4 Oxysterol-binding protein homolog 5 Oxysterol-binding protein homolog 6 Oxysterol-binding protein homolog 7 Putative meiotic phospholipase SPO1	P35843 P35844 P38755 P39105 P53541 Q02201 Q03674 Q08108 Q08548	ALE1 BSR3 HES1 KES1 LCA1 LPT1 OSH4 OSH5 OSH6 OSH7 PLB1 PLB2 PLB3 SLC4 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodelling of PE	Cardiolipin-specific deacylase 1, mitochondrial Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Lysophospholipid acyltransferase Putative meiotic phospholipase SPO1	P39105 P53264 P53541 Q03674 Q08108 Q08548	ALE1 CLD1 LCA1 LPT1 PLB1 PLB2 PLB3 SLC4 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodelling of PI	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Lysophospholipid acyltransferase Putative meiotic phospholipase SPO1	P39105 P53541 Q03674 Q08108 Q08548	ALE1 LCA1 LPT1 PLB1 PLB2 PLB3 SLC4 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodelling of PC	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Lysophospholipid acyltransferase Putative meiotic phospholipase SPO1	P39105 P53541 Q03674 Q08108 Q08548	ALE1 LCA1 LPT1 PLB1 PLB2 PLB3 SLC4 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Alpha-1,2-mannosyltransferase ALG9 Alpha-1,3/1,6-mannosyltransferase ALG2 Chitobiosyldiphosphodolichol beta-mannosyltransferase Dol-P-Man Dol-P-Man Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	P07286 P16661 P38179 P40351 P43636 P53730 P53868 Q12001	ALG1 ALG12 ALG2 ALG3 ALG6 ALG7 ALG8 ALG9 ECM39 RHK1 TUR1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of dolichyl-phosphate-glucose	Dolichyl-phosphate beta-glucosyltransferase	P40350	ALG5	Saccharomyces cerevisiae (brewer's yeast)
Pyruvate metabolism	Glyoxalase I Hydroxyacylglutathione hydrolase, mitochondrial Mitochondrial outer membrane protein porin 1 Mitochondrial outer membrane protein porin 2 Probable alanine aminotransferase, mitochondrial Pyruvate carboxylase 1 Pyruvate kinase 1 Pyruvate kinase 2 Uncharacterized mitochondrial hydrolase FMP41	P00549 P04840 P11154 P40478 P50107 P52489 P52893 P53889 Q12320	ALT1 CDC19 FMP41 GER1 GLO1 GLO4 OMP2 POR1 POR2 PYC1 PYK1 PYK2 PYV VDAC1	Saccharomyces cerevisiae (brewer's yeast)
The NLRP3 inflammasome	ATP-dependent molecular chaperone HSP82 Arrestin-related trafficking adapter 3 Arrestin-related trafficking adapter 5 Arrestin-related trafficking adapter 6 Protein ECM21 Protein LDB19 Protein ROD1 Protein ROG3 Protein SGT1 Thioredoxin-1 Thioredoxin-2 Thioredoxin-3, mitochondrial Transcription factor CSR2 pH-response regulator protein palF/RIM8	P02829 P22217 P22803 P25372 P36117 P38167 P43602 P47029 P53179 P53244 Q02805 Q08446 Q12502 Q12734	ALY1 ALY2 ART3 ART5 ART6 CSR2 ECM21 HSP82 HSP90 LDB19 MRG19 PAL3 RIM8 ROD1 ROG3 SGT1 TRX1 TRX2 TRX3	Saccharomyces cerevisiae (brewer's yeast)
Cargo recognition for clathrin-mediated endocytosis	AP-1 complex subunit beta-1 AP-1 complex subunit mu-1-I AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Autophagy-related protein 27 EH domain-containing and endocytosis protein 1 Epsin-1 Epsin-2 Mannose 6-phosphate receptor-like protein 1 NEDD8-like protein RUB1 Ubiquitin domain-containing protein DSK2	P27351 P34216 P36000 P38065 P46989 P48510 Q00381 Q00776 Q03919 Q05785 Q06815 Q12518 Q99186	AMP1 APL1 APL2 APL3 APM1 APM4 APS2 ATG27 BUD15 DSK2 EDE1 ENT1 ENT2 ETF1 MRL1 RUB1 SHE4 YAP17 YAP54 YAP80	Saccharomyces cerevisiae (brewer's yeast)
Clathrin-mediated endocytosis	AP-1 complex subunit beta-1 AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Actin cytoskeleton-regulatory complex protein END3 Actin cytoskeleton-regulatory complex protein PAN1 Clathrin heavy chain Clathrin light chain Cytokinesis protein 2 EH domain-containing and endocytosis protein 1 Increased rDNA silencing protein 4 Phosphatidylinositol 4-phosphate 5-kinase MSS4 Rho-GTPase-activating protein RGD2 Suppressor of yeast profilin deletion	P17891 P22137 P25623 P27351 P32521 P34216 P36000 P36115 P38065 P38994 P39013 P43556 Q00381 Q05080 Q99186	AMP1 APL1 APL2 APL3 APM4 APS2 BUD15 CHC1 CLC1 CYK2 DIM2 EDE1 END3 HOF1 IRS4 MDP3 MIP3 MSS4 PAN1 RGD2 SYP1 YAP17 YAP80	Saccharomyces cerevisiae (brewer's yeast)
Recycling pathway of L1	AP-1 complex subunit beta-1 AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Clathrin heavy chain Clathrin light chain Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P17891 P22137 P27351 P36000 P38065 P41808 Q00381 Q00772 Q99186	AMP1 APL1 APL2 APL3 APM4 APS2 CHC1 CLC1 DAC2 FUS3 KSS1 MPK1 SLT2 SMK1 YAP17 YAP80	Saccharomyces cerevisiae (brewer's yeast)
LDL clearance	AP-1 complex subunit beta-1 AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Cerevisin Clathrin heavy chain Clathrin light chain NPC intracellular sterol transporter 1-related protein 1 Phosphatidylglycerol/phosphatidylinositol transfer protein Subtilase-type proteinase RRT12 Subtilisin-like protease 3	P09232 P17891 P22137 P25036 P25381 P27351 P36000 P38065 Q00381 Q12200 Q12408 Q99186	AMP1 APL1 APL2 APL3 APM4 APS2 CHC1 CLC1 NCR1 NPC2 OSW3 PRB1 RRT12 YAP17 YAP80 YSP3	Saccharomyces cerevisiae (brewer's yeast)
VLDLR internalisation and degradation	AP-1 complex subunit beta-1 AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Cerevisin Clathrin heavy chain Clathrin light chain Subtilase-type proteinase RRT12 Subtilisin-like protease 3	P09232 P17891 P22137 P25036 P25381 P27351 P36000 P38065 Q00381 Q99186	AMP1 APL1 APL2 APL3 APM4 APS2 CHC1 CLC1 OSW3 PRB1 RRT12 YAP17 YAP80 YSP3	Saccharomyces cerevisiae (brewer's yeast)
Lysosomal oligosaccharide catabolism	Alpha-mannosidase	P22855	AMS1	Saccharomyces cerevisiae (brewer's yeast)	G25577BM G28233ME G70323CJ
Association of TriC/CCT with target proteins during biosynthesis	Sphingoid long chain base kinase 5 T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta	P12612 P39076 P39077 P39078 P39079 P40413 P42943 P47079 Q06147	ANC2 BIN2 BIN3 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT7 CCT8 LCB5 TCP1 TCP2 TCP20 TCP3 TCP4 TCP5 TCP6	Saccharomyces cerevisiae (brewer's yeast)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Guanine nucleotide-binding protein subunit beta T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta	P12612 P18851 P39076 P39077 P39078 P39079 P40413 P42943 P47079	ANC2 BIN2 BIN3 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT7 CCT8 STE4 TCP1 TCP2 TCP20 TCP3 TCP4 TCP5 TCP6	Saccharomyces cerevisiae (brewer's yeast)
COPII-mediated vesicle transport	Alpha-soluble NSF attachment protein COPII coat assembly protein SEC16 Casein kinase I homolog HRR25 GRASP65 homolog protein 1 GTP-binding protein YPT11 GTP-binding protein YPT1 GTPase-activating protein GYP8 Guanine nucleotide-exchange factor SEC12 Integral membrane protein SED5 Intracellular protein transport protein USO1 Phosphate system positive regulatory protein PHO81 Probable phospholipase YOR022C, mitochondrial Protein HOS4 Protein SLY1 Protein transport protein BET1 Protein transport protein BOS1 Protein transport protein SEC13 Protein transport protein SEC22 Protein transport protein SEC23 Protein transport protein SEC24 Protein transport protein SEC31 SED5-binding protein 2 SED5-binding protein 3 SIT4-associating protein SAP155 SIT4-associating protein SAP185 SIT4-associating protein SAP190 SIT4-associating protein SAP4 Serine/threonine-protein phosphatase PP1-1 Small COPII coat GTPase SAR1 Synaptobrevin homolog YKT6 Syntaxin PEP12 Syntaxin VAM3 TRAPP-associated protein TCA17 Trafficking protein particle complex II-specific subunit 120 Trafficking protein particle complex II-specific subunit 130 Trafficking protein particle complex subunit 20 Trafficking protein particle complex subunit 23 Trafficking protein particle complex subunit 31 Trafficking protein particle complex subunit 33 Trafficking protein particle complex subunit BET3 Trafficking protein particle complex subunit BET5 Vesicular-fusion protein SEC18	P01123 P11655 P15303 P17442 P18759 P20604 P20606 P22213 P22214 P22804 P25385 P25386 P29295 P32602 P32613 P32854 P36015 P36123 P36149 P38334 P38810 P38968 P40480 P40482 P40856 P43570 P43612 P48415 P48559 P53036 P53953 Q01590 Q03337 Q03630 Q03660 Q03784 Q04183 Q04410 Q04491 Q12204 Q12241 Q99394	ANU1 ANU3 BET1 BET3 BET5 BOS1 GRH1 GYP8 HOS4 HRR25 INT1 ISS1 LST1 PEP12 PHO81 PPH1 PTH1 SAP155 SAP185 SAP190 SAP4 SAR1 SEC12 SEC13 SEC16 SEC17 SEC18 SEC22 SEC23 SEC24 SEC31 SED2 SED5 SFB2 SFB3 SIT4 SLY1 SLY12 SLY2 TCA17 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33 TSL26 USO1 VAM3 VPS6 VPT13 WEB1 YKT6 YOR022C YP2 YPT1 YPT11	Saccharomyces cerevisiae (brewer's yeast)
Regulation of HSF1-mediated heat shock response	Endoplasmic reticulum chaperone BiP Heat shock protein SSA1 Heat shock protein SSA2 Heat shock protein SSA3 Heat shock protein SSA4 Heat shock protein homolog SSE1 Heat shock protein homolog SSE2 Heat shock transcription factor Import motor subunit, mitochondrial Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Nucleoporin ASM4 Nucleoporin NDC1 Nucleoporin NIC96 Nucleoporin NSP1 Nucleoporin NUP116/NSP116 Nucleoporin NUP120 Nucleoporin NUP133 Nucleoporin NUP170 Nucleoporin NUP188 Nucleoporin NUP192 Nucleoporin NUP1 Nucleoporin NUP2 Nucleoporin NUP42 Nucleoporin NUP57 Nucleoporin NUP82 Nucleoporin NUP84 Nucleoporin NUP85 Nucleoporin SEH1 Protein BMH2 Protein MLP1 Protein OPI10 Protein kinase MCK1 Protein transport protein SEC13 Ran-specific GTPase-activating protein 1 Ran-specific GTPase-activating protein 2 Ribosome-associated molecular chaperone SSB1 Ribosome-associated molecular chaperone SSB2 Serine/threonine-protein kinase MRK1 Serine/threonine-protein kinase RIM11/MSD1 Sporulation-specific mitogen-activated protein kinase SMK1 Zuotin mRNA export factor GLE2	P09435 P0CS90 P10591 P10592 P10961 P11484 P14681 P14907 P16474 P16892 P20676 P21965 P22202 P32499 P32500 P32527 P32589 P32590 P34077 P34730 P35729 P36161 P38181 P38615 P40066 P40150 P40368 P40517 P41808 P41920 P46673 P47054 P48837 P49686 P50873 P52593 P52891 P53011 Q00772 Q02455 Q02630 Q04491 Q05166 Q08202	ANU3 ASM4 BMH2 CST20 DAC2 ENS1 FUS3 GLE2 GRP78 GSK3 HSF1 HSP HTN1 KAR2 KSS1 MCK1 MDS1 MLP1 MPK1 MRK1 MSI3 NDC1 NIC96 NLE3 NSP1 NSP116 NUP1 NUP116 NUP120 NUP133 NUP170 NUP188 NUP192 NUP2 NUP42 NUP57 NUP59 NUP82 NUP84 NUP85 OPI10 RAE1 RAT2 RAT3 RAT9 RIM11 RIP1 SEC13 SEH1 SFO1 SLT2 SMK1 SSA1 SSA2 SSA3 SSA4 SSB1 SSB2 SSC1 SSD1 SSE1 SSE2 UIP1 YG101 YG103 YPK1 YRB1 YRB2 ZUO1	Saccharomyces cerevisiae (brewer's yeast)

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