GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **250** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Beta-oxidation of pristanoyl-CoA	Acyl-coenzyme A oxidase Peroxisomal acyl-coenzyme A thioester hydrolase 1	P13711 P41903	FOX1 POX1 PTE1 TES1	Saccharomyces cerevisiae (brewer's yeast)
Beta-oxidation of very long chain fatty acids	3,2-trans-enoyl-CoA isomerase 3-ketoacyl-CoA thiolase, peroxisomal Peroxisomal 2,4-dienoyl-CoA reductase SPS19 [(3E)-enoyl-CoA-producing] Peroxisomal acyl-coenzyme A thioester hydrolase 1 Peroxisomal long-chain fatty acid import protein 2	P27796 P32573 P41903 P41909 Q05871	ECI1 FOX3 PAL1 PAT2 POT1 POX3 PTE1 PXA1 SPS19 SPX19 SSH2 TES1	Saccharomyces cerevisiae (brewer's yeast)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Alpha-1,2-mannosyltransferase ALG9 Alpha-1,3/1,6-mannosyltransferase ALG2 Chitobiosyldiphosphodolichol beta-mannosyltransferase Dol-P-Man Dol-P-Man Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	P07286 P16661 P38179 P40351 P43636 P53730 P53868 Q12001	ALG1 ALG12 ALG2 ALG3 ALG6 ALG7 ALG8 ALG9 ECM39 RHK1 TUR1	Saccharomyces cerevisiae (brewer's yeast)
Biotin transport and metabolism	Acetyl-CoA carboxylase, mitochondrial Acetyl-CoA carboxylase Biotin--protein ligase Pyruvate carboxylase 1	P11154 P32874 P48445 Q00955	ABP2 ACC1 ACC2 BPL1 FAS3 HFA1 MTR7 PYC1 PYV	Saccharomyces cerevisiae (brewer's yeast)
Branched-chain amino acid catabolism	Branched-chain-amino-acid aminotransferase, cytosolic Branched-chain-amino-acid aminotransferase, mitochondrial Small ribosomal subunit protein mS47	P28817 P38891 P47176	BAT1 BAT2 ECA39 EHD3 MRP5 TWT1 TWT2	Saccharomyces cerevisiae (brewer's yeast)
CD28 dependent PI3K/Akt signaling	Probable target of rapamycin complex 2 subunit BIT2 Serine/threonine-protein kinase BCK1/SLK1/SSP31 Serine/threonine-protein kinase PKH2 Serine/threonine-protein kinase SCH9 Serine/threonine-protein kinase TOR2 Serine/threonine-protein kinase YPK1 Target of rapamycin complex 2 subunit AVO1 Target of rapamycin complex 2 subunit BIT61 Target of rapamycin complex 2 subunit TSC11 Target of rapamycin complex subunit LST8	P11792 P12688 P32600 P38346 P40061 P41318 P47041 Q01389 Q08236 Q12236	AVO1 AVO3 BCK1 BIT2 BIT61 DRR2 KOM1 LAS3 LST8 PKH2 SCH9 SLI2 SLK1 SSP31 TOR2 TSC11 TSC14 YPK1	Saccharomyces cerevisiae (brewer's yeast)
CD28 dependent Vav1 pathway	Cell division control protein 42 Serine/threonine-protein kinase CLA4 Serine/threonine-protein kinase SKM1 Serine/threonine-protein kinase STE20	P19073 P48562 Q03497 Q12469	CDC42 CLA4 SKM1 SRO2 STE20	Saccharomyces cerevisiae (brewer's yeast)
CDC42 GTPase cycle	Actin cytoskeleton-regulatory complex protein END3 Actin cytoskeleton-regulatory complex protein PAN1 Cell division control protein 42 EH domain-containing and endocytosis protein 1 GTPase-activating protein BEM2/IPL2 GTPase-activating protein BEM3 GTPase-activating protein SAC7 Guanine nucleotide-binding protein alpha-1 subunit Increased rDNA silencing protein 4 Nuclear fusion protein FUS2 Protein ECM25 RHO GTPase-activating protein RGD1 Rho GDP-dissociation inhibitor Rho-GTPase-activating protein BAG7 Rho-type GTPase-activating protein 1 Rho-type GTPase-activating protein 2 Uncharacterized protein YHR182W	P08539 P17121 P19073 P32521 P32525 P32873 P34216 P36115 P38339 P38870 P39013 P39083 P39960 Q05670 Q06407 Q12128 Q12434	BAG7 BEM2 BEM3 BUD15 CDC42 CDC70 DAC1 DBM1 DIM2 ECM25 EDE1 END3 FUS2 GPA1 IPL2 IRS4 MDP3 MIP3 PAN1 RDI1 RGA1 RGA2 RGD1 SAC7 SCG1 SRO2 SUP9 THE1 YHR182W	Saccharomyces cerevisiae (brewer's yeast)
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 Protein kinase C-like 1	P24583 P32383	HPO2 PKC1 PLC1 STT1	Saccharomyces cerevisiae (brewer's yeast)
COPI-dependent Golgi-to-ER retrograde traffic	ADP-ribosylation factor 1 ADP-ribosylation factor 2 ADP-ribosylation factor GTPase-activating protein GCS1 ADP-ribosylation factor GTPase-activating protein GLO3 ARF guanine-nucleotide exchange factor 2 Alpha-soluble NSF attachment protein Coatomer subunit alpha Coatomer subunit beta' Coatomer subunit beta Coatomer subunit delta Coatomer subunit epsilon Coatomer subunit gamma Coatomer subunit zeta ER lumen protein-retaining receptor ER-derived vesicles protein ERV29 Endoplasmic reticulum vesicle protein 25 Endosomal protein P24B GTP-binding protein YPT11 GTP-binding protein YPT1 Protein ERP1 Protein ERP2 Protein ERP3 Protein ERP4 Protein ERP5 Protein ERP6 Protein transport protein DSL1 Protein transport protein SEC20 Protein transport protein SEC22 Protein transport protein TIP20 Protein transport protein USE1 Sporulation protein SPS18 Syntaxin UFE1 Vesicular-fusion protein SEC18	P01123 P11076 P18414 P18759 P19146 P22214 P28791 P32074 P32572 P32602 P32803 P33891 P35197 P38682 P38819 P39704 P39993 P40509 P41810 P41811 P41834 P43621 P48559 P53146 P53198 P53337 P53600 P53622 P53847 P54837 Q05359 Q12403 Q12450	ARF1 ARF2 COP1 DSL1 EMP24 ERD2 ERP1 ERP2 ERP3 ERP4 ERP5 ERP6 ERV25 ERV29 GCS1 GEA2 GLO3 RET1 RET2 RET3 SEC17 SEC18 SEC20 SEC21 SEC22 SEC26 SEC27 SEC28 SEC33 SLT1 SLY2 SOO1 SPS18 SPX18 TIP1 TIP20 TSL26 UFE1 USE1 YP2 YPT1 YPT11	Saccharomyces cerevisiae (brewer's yeast)
COPI-independent Golgi-to-ER retrograde traffic	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Protein MUM3 Putative meiotic phospholipase SPO1	P39105 P53541 Q03674 Q08108 Q08750	MUM3 PLB1 PLB2 PLB3 SPO1	Saccharomyces cerevisiae (brewer's yeast)
COPI-mediated anterograde transport	ADP-ribosylation factor 1 ADP-ribosylation factor 2 ADP-ribosylation factor GTPase-activating protein GCS1 ADP-ribosylation factor GTPase-activating protein GLO3 ARF guanine-nucleotide exchange factor 2 Alpha-soluble NSF attachment protein Coatomer subunit alpha Coatomer subunit beta' Coatomer subunit beta Coatomer subunit delta Coatomer subunit epsilon Coatomer subunit gamma Coatomer subunit zeta ER lumen protein-retaining receptor Endoplasmic reticulum vesicle protein 25 Endosomal protein P24B GTP-binding protein YPT11 GTP-binding protein YPT1 Golgi SNAP receptor complex member 1 Integral membrane protein SED5 Intracellular protein transport protein USO1 Protein ERP1 Protein ERP2 Protein ERP3 Protein ERP4 Protein ERP5 Protein ERP6 Protein transport protein BET1 Protein transport protein BOS1 Protein transport protein SFT1 Sporulation protein SPS18 Synaptobrevin homolog YKT6 Vesicular-fusion protein SEC18	P01123 P11076 P18414 P18759 P19146 P22804 P25385 P25386 P32074 P32572 P32602 P32803 P35197 P36015 P38682 P38736 P38819 P39704 P39993 P40509 P41810 P41811 P43621 P43682 P48559 P53198 P53600 P53622 P54837 Q01590 Q05359 Q12403 Q12450	ARF1 ARF2 BET1 BOS1 COP1 EMP24 ERD2 ERP1 ERP2 ERP3 ERP4 ERP5 ERP6 ERV25 GCS1 GEA2 GLO3 GOS1 INT1 RET1 RET2 RET3 SEC17 SEC18 SEC21 SEC26 SEC27 SEC28 SEC33 SED5 SFT1 SLY12 SOO1 SPS18 SPX18 USO1 YKT6 YP2 YPT1 YPT11	Saccharomyces cerevisiae (brewer's yeast)
COPII-mediated vesicle transport	Alpha-soluble NSF attachment protein COPII coat assembly protein SEC16 Casein kinase I homolog HRR25 GRASP65 homolog protein 1 GTP-binding protein YPT11 GTP-binding protein YPT1 GTPase-activating protein GYP8 Guanine nucleotide-exchange factor SEC12 Integral membrane protein SED5 Intracellular protein transport protein USO1 Phosphate system positive regulatory protein PHO81 Probable phospholipase YOR022C, mitochondrial Protein HOS4 Protein SLY1 Protein transport protein BET1 Protein transport protein BOS1 Protein transport protein SEC13 Protein transport protein SEC22 Protein transport protein SEC23 Protein transport protein SEC24 Protein transport protein SEC31 SED5-binding protein 2 SED5-binding protein 3 SIT4-associating protein SAP155 SIT4-associating protein SAP185 SIT4-associating protein SAP190 SIT4-associating protein SAP4 Serine/threonine-protein phosphatase PP1-1 Small COPII coat GTPase SAR1 Synaptobrevin homolog YKT6 Syntaxin PEP12 Syntaxin VAM3 TRAPP-associated protein TCA17 Trafficking protein particle complex II-specific subunit 120 Trafficking protein particle complex II-specific subunit 130 Trafficking protein particle complex subunit 20 Trafficking protein particle complex subunit 23 Trafficking protein particle complex subunit 31 Trafficking protein particle complex subunit 33 Trafficking protein particle complex subunit BET3 Trafficking protein particle complex subunit BET5 Vesicular-fusion protein SEC18	P01123 P11655 P15303 P17442 P18759 P20604 P20606 P22213 P22214 P22804 P25385 P25386 P29295 P32602 P32613 P32854 P36015 P36123 P36149 P38334 P38810 P38968 P40480 P40482 P40856 P43570 P43612 P48415 P48559 P53036 P53953 Q01590 Q03337 Q03630 Q03660 Q03784 Q04183 Q04410 Q04491 Q12204 Q12241 Q99394	ANU1 ANU3 BET1 BET3 BET5 BOS1 GRH1 GYP8 HOS4 HRR25 INT1 ISS1 LST1 PEP12 PHO81 PPH1 PTH1 SAP155 SAP185 SAP190 SAP4 SAR1 SEC12 SEC13 SEC16 SEC17 SEC18 SEC22 SEC23 SEC24 SEC31 SED2 SED5 SFB2 SFB3 SIT4 SLY1 SLY12 SLY2 TCA17 TRS120 TRS130 TRS20 TRS23 TRS31 TRS33 TSL26 USO1 VAM3 VPS6 VPT13 WEB1 YKT6 YOR022C YP2 YPT1 YPT11	Saccharomyces cerevisiae (brewer's yeast)
CTLA4 inhibitory signaling	Protein phosphatase PP2A regulatory subunit A Serine/threonine-protein kinase SCH9 Serine/threonine-protein kinase YPK1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase PP2A-1 catalytic subunit	P11792 P12688 P23594 P31383 P38903	KOM1 PPH21 RTS1 SCH9 SCS1 SLI2 TPD3 YPK1	Saccharomyces cerevisiae (brewer's yeast)
Calnexin/calreticulin cycle	Calnexin homolog Protein disulfide-isomerase	P17967 P27825	CNE1 MFP1 PDI1 TRG1	Saccharomyces cerevisiae (brewer's yeast)
Cargo recognition for clathrin-mediated endocytosis	AP-1 complex subunit beta-1 AP-1 complex subunit mu-1-I AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Autophagy-related protein 27 EH domain-containing and endocytosis protein 1 Epsin-1 Epsin-2 Mannose 6-phosphate receptor-like protein 1 NEDD8-like protein RUB1 Ubiquitin domain-containing protein DSK2	P27351 P34216 P36000 P38065 P46989 P48510 Q00381 Q00776 Q03919 Q05785 Q06815 Q12518 Q99186	AMP1 APL1 APL2 APL3 APM1 APM4 APS2 ATG27 BUD15 DSK2 EDE1 ENT1 ENT2 ETF1 MRL1 RUB1 SHE4 YAP17 YAP54 YAP80	Saccharomyces cerevisiae (brewer's yeast)
Cellular hexose transport	Probable metabolite transport protein YBR241C Vacuolar protein sorting-associated protein 73	P38142 P53142	VPS73 YBR241C	Saccharomyces cerevisiae (brewer's yeast)	G58161NS
Cholesterol biosynthesis	3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 Acetyl-CoA acetyltransferase C-4 methylsterol oxidase ERG25 Delta(14)-sterol reductase ERG24 Diphosphomevalonate decarboxylase Dolichyldiphosphatase Farnesyl pyrophosphate synthase Geranylgeranyl pyrophosphate synthase BTS1 Hydroxymethylglutaryl-CoA synthase Isopentenyl-diphosphate delta-isomerase Lanosterol 14-alpha demethylase CYP51 Lanosterol synthase ERG7 Mevalonate kinase Protein ARV1 Squalene epoxidase ERG1 Squalene synthase ERG9 Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating	P07277 P08524 P10614 P12683 P15496 P29704 P32377 P32462 P32476 P38604 P41338 P53045 P53199 P53223 P54839 Q06541 Q12051	ARV1 BOT2 BOT3 BTS1 CAX4 CWH8 CYP51 ERG1 ERG10 ERG11 ERG12 ERG13 ERG19 ERG20 ERG24 ERG25 ERG26 ERG7 ERG9 FDS1 FET6 FPP1 HMG1 HMGS IDI1 MPD MVD1 RAR1	Saccharomyces cerevisiae (brewer's yeast)
Ciprofloxacin ADME	Probable ATP-dependent permease	P25371	ADP1	Saccharomyces cerevisiae (brewer's yeast)
Citric acid cycle (TCA cycle)	Aconitate hydratase, mitochondrial Citrate synthase, mitochondrial Fumarate hydratase, mitochondrial Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial Malate dehydrogenase, cytoplasmic Mitochondrial import inner membrane translocase subunit TIM18 Succinate dehydrogenase [ubiquinone] cytochrome b subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	P00890 P08417 P19414 P21801 P22133 P28241 P28834 P33421 P53312 P53598 Q00711 Q08749	ACO1 CIT1 CYB3 FUM1 GLU1 GLU3 IDH1 IDH2 LSC1 LSC2 LYS6 MDH2 SDH SDH1 SDH2 SDH3 SDHA SDHB TIM18	Saccharomyces cerevisiae (brewer's yeast)
Class I peroxisomal membrane protein import	Fatty aldehyde dehydrogenase HFD1 Mitochondrial fission 1 protein Outer mitochondrial transmembrane helix translocase Peroxisomal biogenesis factor 3 Peroxisomal long-chain fatty acid import protein 1 Peroxisomal long-chain fatty acid import protein 2 Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal membrane protein PMP27 Peroxisomal membrane protein import receptor PEX19 Peroxisome assembly protein 12	P28737 P28795 P34230 P40515 P41909 P53112 P80667 Q04370 Q04458 Q07418 Q12462	FIS1 HFD1 MDV2 MSP1 PAL1 PAS12 PAS20 PAS3 PAT1 PAT2 PEX11 PEX12 PEX13 PEX14 PEX19 PEX3 PMP24 PMP27 PXA1 PXA2 SSH2 YTA4	Saccharomyces cerevisiae (brewer's yeast)
Clathrin-mediated endocytosis	AP-1 complex subunit beta-1 AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Actin cytoskeleton-regulatory complex protein END3 Actin cytoskeleton-regulatory complex protein PAN1 Clathrin heavy chain Clathrin light chain Cytokinesis protein 2 EH domain-containing and endocytosis protein 1 Increased rDNA silencing protein 4 Phosphatidylinositol 4-phosphate 5-kinase MSS4 Rho-GTPase-activating protein RGD2 Suppressor of yeast profilin deletion	P17891 P22137 P25623 P27351 P32521 P34216 P36000 P36115 P38065 P38994 P39013 P43556 Q00381 Q05080 Q99186	AMP1 APL1 APL2 APL3 APM4 APS2 BUD15 CHC1 CLC1 CYK2 DIM2 EDE1 END3 HOF1 IRS4 MDP3 MIP3 MSS4 PAN1 RGD2 SYP1 YAP17 YAP80	Saccharomyces cerevisiae (brewer's yeast)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Guanine nucleotide-binding protein subunit beta T-complex protein 1 subunit alpha T-complex protein 1 subunit beta T-complex protein 1 subunit delta T-complex protein 1 subunit epsilon T-complex protein 1 subunit eta T-complex protein 1 subunit gamma T-complex protein 1 subunit theta T-complex protein 1 subunit zeta	P12612 P18851 P39076 P39077 P39078 P39079 P40413 P42943 P47079	ANC2 BIN2 BIN3 CCT1 CCT2 CCT3 CCT4 CCT5 CCT6 CCT7 CCT8 STE4 TCP1 TCP2 TCP20 TCP3 TCP4 TCP5 TCP6	Saccharomyces cerevisiae (brewer's yeast)
Cytoprotection by HMOX1	Oligomycin resistance ATP-dependent permease YOR1	P53049	YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
DNA Damage/Telomere Stress Induced Senescence	DNA repair protein RAD50 Double-strand break repair protein MRE11 Histone acetyltransferase ESA1 Serine/threonine-protein kinase TEL1	P12753 P32829 P38110 Q08649	ESA1 MRE11 RAD50 TEL1	Saccharomyces cerevisiae (brewer's yeast)

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