GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **76 - 100** of **250** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Signal transduction by L1	MAP kinase kinase MKK1/SSP32 MAP kinase kinase MKK2/SSP33 MAP kinase kinase PBS2 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Serine/threonine-protein kinase STE7 Sporulation-specific mitogen-activated protein kinase SMK1	P06784 P08018 P14681 P16892 P32490 P32491 P41808 Q00772	DAC2 FUS3 HOG4 KSS1 MKK1 MKK2 MPK1 PBS2 SFS4 SLT2 SMK1 SSK4 SSP32 SSP33 STE7	Saccharomyces cerevisiae (brewer's yeast)
MAPK1 (ERK2) activation	MAP kinase kinase MKK1/SSP32 MAP kinase kinase MKK2/SSP33 MAP kinase kinase PBS2 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Serine/threonine-protein kinase STE7 Sporulation-specific mitogen-activated protein kinase SMK1	P06784 P08018 P14681 P16892 P32490 P32491 P41808 Q00772	DAC2 FUS3 HOG4 KSS1 MKK1 MKK2 MPK1 PBS2 SFS4 SLT2 SMK1 SSK4 SSP32 SSP33 STE7	Saccharomyces cerevisiae (brewer's yeast)
Negative feedback regulation of MAPK pathway	MAP kinase kinase MKK1/SSP32 MAP kinase kinase MKK2/SSP33 MAP kinase kinase PBS2 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Serine/threonine-protein kinase STE7 Sporulation-specific mitogen-activated protein kinase SMK1	P06784 P08018 P14681 P16892 P32490 P32491 P41808 Q00772	DAC2 FUS3 HOG4 KSS1 MKK1 MKK2 MPK1 PBS2 SFS4 SLT2 SMK1 SSK4 SSP32 SSP33 STE7	Saccharomyces cerevisiae (brewer's yeast)
MAP2K and MAPK activation	MAP kinase kinase MKK1/SSP32 MAP kinase kinase MKK2/SSP33 MAP kinase kinase PBS2 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Serine/threonine-protein kinase STE7 Sporulation-specific mitogen-activated protein kinase SMK1	P06784 P08018 P14681 P16892 P32490 P32491 P41808 Q00772	DAC2 FUS3 HOG4 KSS1 MKK1 MKK2 MPK1 PBS2 SFS4 SLT2 SMK1 SSK4 SSP32 SSP33 STE7	Saccharomyces cerevisiae (brewer's yeast)
ERK/MAPK targets	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase HOG1 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Protein phosphatase PP2A regulatory subunit A Serine/threonine-protein kinase YPK3 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase PP2A-1 catalytic subunit Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P23594 P31383 P32485 P38070 P38903 P41808 Q00772	DAC2 FUS3 HOG1 KSS1 MPK1 PPH21 RTS1 SCS1 SLT2 SMK1 SSK3 TPD3 YPK3	Saccharomyces cerevisiae (brewer's yeast)
RHOC GTPase cycle	Delta(14)-sterol reductase ERG24 GTP-binding protein RHO1 GTP-binding protein RHO2 GTP-binding protein RHO3 GTP-binding protein RHO4 Integral membrane protein SED5 Mitochondrial acidic protein MAM33 Protein ECM25 Protein EMP46 Protein EMP47 Protein UIP5 Protein kinase C-like 1 Putative zinc metalloprotease TRE2 Ras GTPase-activating-like protein IQG1 Rho GDP-dissociation inhibitor Uncharacterized protein TRE1 Vacuolar protein sorting-associated protein 70 Vesicle-associated membrane protein-associated protein SCS22 Vesicle-associated membrane protein-associated protein SCS2	P06780 P06781 P24583 P32462 P32525 P36137 P40075 P40513 P43555 P47161 Q00245 Q00246 Q01590 Q08693 Q08919 Q12280 Q12396 Q12434 Q6Q595	CYK1 ECM25 EMP46 EMP47 ERG24 HPO2 IQG1 MAM33 PKC1 RDI1 RHO1 RHO2 RHO3 RHO4 SCS2 SCS22 SED5 STT1 TRE1 TRE2 UIP5 VPS70	Saccharomyces cerevisiae (brewer's yeast)
Digestion of dietary carbohydrate	Sporulation-specific chitinase 2	Q06350	CTS2	Saccharomyces cerevisiae (brewer's yeast)	G80384UV
Acyl chain remodeling of CL	2-acyl-1-lysophosphatidylinositol acyltransferase Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Putative meiotic phospholipase SPO1 Tafazzin	P38226 P39105 P53541 Q03674 Q06510 Q08108	CST26 PLB1 PLB2 PLB3 PSI1 SPO1 TAZ1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PA	1-acyl-sn-glycerol-3-phosphate acyltransferase 2-acyl-1-lysophosphatidylinositol acyltransferase Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 Glycerol-3-phosphate dehydrogenase [NAD(+)] 2, mitochondrial Glycerol-3-phosphate dehydrogenase, mitochondrial Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Phospholipase D1 Probable phospholipase YOR022C, mitochondrial Protein MUM3 Putative meiotic phospholipase SPO1	P32191 P33333 P36126 P38226 P39105 P41911 P53541 Q00055 Q03674 Q08108 Q08750 Q12204	CST26 DAR1 GPD1 GPD2 GPD3 GUT2 HOR1 MUM3 OSG1 PLB1 PLB2 PLB3 PLD1 PSI1 SLC1 SPO1 SPO14 YOR022C	Saccharomyces cerevisiae (brewer's yeast)
SUMOylation of transcription factors	DNA repair protein RAD9 E3 SUMO-protein ligase SIZ1 E3 SUMO-protein ligase SIZ2 Fork head protein homolog 1 Forkhead transcription factor HCM1 Retrograde regulation protein 3 SUMO-conjugating enzyme UBC9 Transcriptional regulator CRZ1 Ubiquitin-like protein SMT3	P14737 P25364 P38165 P40466 P50623 P53968 Q04195 Q12216 Q12306	CRZ1 FKH1 HAL8 HCM1 NFI1 RAD9 RTG3 SIZ1 SIZ2 SMT3 TCN1 UBC9 ULL1	Saccharomyces cerevisiae (brewer's yeast)
HDMs demethylate histones	DNA damage-responsive transcriptional repressor RPH1 General transcriptional corepressor CYC8 Histone H3-like centromeric protein CSE4 Histone demethylase JHD2 Polyamine oxidase FMS1 Transcriptional activator/repressor GIS1	P14922 P36012 P39956 P47156 P50264 Q03833	CRT8 CSE4 CSL2 CYC8 FMS1 GIS1 JHD2 RPH1 SSN6	Saccharomyces cerevisiae (brewer's yeast)
Transcriptional and post-translational regulation of MITF-M expression and activity	Exportin-1 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Protein kinase MCK1 Retrograde regulation protein 3 Serine/threonine-protein kinase MRK1 Serine/threonine-protein kinase RIM11/MSD1 Serine/threonine-protein kinase YPK3 Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P21965 P30822 P38070 P38165 P38615 P41808 P50873 Q00772	CRM1 DAC2 FUS3 GSK3 KAP124 KSS1 MCK1 MDS1 MPK1 MRK1 RIM11 RTG3 SLT2 SMK1 XPO1 YPK1 YPK3	Saccharomyces cerevisiae (brewer's yeast)
Oleoyl-phe metabolism	Carboxypeptidase S	P27614	CPS CPS1	Saccharomyces cerevisiae (brewer's yeast)
Peroxisomal protein import	2-hydroxyacyl-CoA lyase 3,2-trans-enoyl-CoA isomerase 3-ketoacyl-CoA thiolase, peroxisomal A-factor-processing enzyme Acyl-coenzyme A oxidase Isocitrate dehydrogenase [NADP], mitochondrial NADPH--cytochrome P450 reductase Peroxisomal 2,4-dienoyl-CoA reductase SPS19 [(3E)-enoyl-CoA-producing] Peroxisomal acyl-coenzyme A thioester hydrolase 1 Peroxisomal catalase A Peroxisomal coenzyme A diphosphatase 1, peroxisomal Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal targeting signal 2 receptor Peroxisomal targeting signal receptor Peroxisome assembly protein 12 Peroxisome biogenesis factor 10 Polyubiquitin Protein SYM1 Ubiquitin-conjugating enzyme E2 4 Ubiquitin-conjugating enzyme E2-16 kDa Uncharacterized protein YJR154W Very long-chain fatty acid transport protein	P0CG63 P13711 P15202 P15731 P15732 P16603 P21954 P27796 P32573 P35056 P38225 P39108 P39994 P41903 P47181 P53112 P80667 Q04370 Q05568 Q05871 Q06010 Q06563 Q12524	CPR1 CTA1 ECI1 FAT1 FOX1 FOX3 IDP1 NCP1 NCPR1 PAS10 PAS20 PAS4 PAS7 PCD1 PEB1 PEX10 PEX12 PEX13 PEX14 PEX5 PEX7 POT1 POX1 POX3 PRD1 PTE1 PXP1 SCD2 SPS19 SPX19 STE23 SYM1 TES1 UBC4 UBC5 UBI4 YJR154W	Saccharomyces cerevisiae (brewer's yeast)
Metal ion SLC transporters	Copper transport protein CTR2 Vacuolar zinc transporter COT1 Vacuolar zinc transporter ZRC1	P20107 P32798 P38865	COT1 CTR2 ZRC1	Saccharomyces cerevisiae (brewer's yeast)
Calnexin/calreticulin cycle	Calnexin homolog Protein disulfide-isomerase	P17967 P27825	CNE1 MFP1 PDI1 TRG1	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodelling of PG	2-acyl-1-lysophosphatidylinositol acyltransferase Cardiolipin synthase (CMP-forming) Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Putative meiotic phospholipase SPO1 Uncharacterized acyltransferase YDR018C	P38226 P39105 P53541 Q03674 Q07560 Q08108 Q12185	CLS1 CRD1 CST26 PLB1 PLB2 PLB3 PSI1 SPO1 YDR018C	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PE	Choline kinase Choline/ethanolaminephosphotransferase 1 Cholinephosphotransferase 1 Ethanolamine kinase Ethanolamine-phosphate cytidylyltransferase Phosphatidic acid phosphohydrolase 1	P17898 P20485 P22140 P32567 P33412 Q03764	CKI CKI1 CPT1 ECT1 EKI1 EPT1 MUQ1 PAH1 PAP1 SMP2	Saccharomyces cerevisiae (brewer's yeast)
Aflatoxin activation and detoxification	Glutathione hydrolase proenzyme	Q05902	CIS2 ECM38	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Glutathione hydrolase proenzyme Leucine aminopeptidase 2 Oligomycin resistance ATP-dependent permease YOR1	P53049 Q05902 Q10740	CIS2 ECM38 LAP2 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
Glutathione synthesis and recycling	5-oxoprolinase Cys-Gly metallodipeptidase DUG1 Glutathione hydrolase proenzyme Glutathione synthetase GSH2 Glutathione-specific gamma-glutamylcyclotransferase	P28273 P32656 P43616 Q05902 Q08220	CIS2 DUG1 ECM38 GCG1 GSH2 OXP1	Saccharomyces cerevisiae (brewer's yeast)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	DNA damage response protein kinase DUN1 DNA damage-responsive transcriptional repressor RPH1 DNA repair protein RAD50 DNA repair protein RAD9 Double-strand break repair protein MRE11 E3 SUMO-protein ligase SIZ1 E3 SUMO-protein ligase SIZ2 E3 ubiquitin-protein ligase DMA2 Histone H2A.1 Histone H2A.2 Histone H2B.1 Histone H2B.2 Histone H3-like centromeric protein CSE4 Histone H4 Histone acetyltransferase ESA1 Histone-lysine N-methyltransferase, H3 lysine-36 specific Polyubiquitin SUMO-conjugating enzyme UBC9 Serine/threonine-protein kinase RCK1 Serine/threonine-protein kinase TEL1 Serine/threonine-protein phosphatase T Transcriptional activator/repressor GIS1 Ubiquitin-conjugating enzyme E2 13 Ubiquitin-conjugating enzyme variant MMS2 Ubiquitin-like protein SMT3	P02293 P02294 P02309 P04911 P04912 P0CG63 P12753 P14737 P32829 P36012 P38110 P38622 P39009 P39956 P46995 P50623 P52490 P53043 P53152 P53924 Q03833 Q04195 Q08649 Q12216 Q12306	CHF2 CSE4 CSL2 DMA2 DUN1 ESA1 EZL1 GIS1 H2A1 H2A2 H2B1 H2B2 HHF1 HHF2 HTA1 HTA2 HTB1 HTB2 KMT3 MMS2 MRE11 NFI1 PPT1 RAD50 RAD9 RCK1 RPH1 SCD2 SET2 SIZ1 SIZ2 SMT3 SPT11 SPT12 TEL1 UBC13 UBC9 UBI4 ULL1	Saccharomyces cerevisiae (brewer's yeast)
Pyrimidine salvage	Cytidine deaminase Probable pseudouridine-5'-phosphatase YKL033W-A Putative uridine kinase DAS2 Uridine kinase	P27515 Q06549 Q12084 Q86ZR7	CDD1 DAS2 RRT3 URK1 YKL033W-A	Saccharomyces cerevisiae (brewer's yeast)
PLC beta mediated events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 Guanine nucleotide-binding protein alpha-1 subunit	P08539 P32383	CDC70 DAC1 GPA1 PLC1 SCG1	Saccharomyces cerevisiae (brewer's yeast)
ADP signalling through P2Y purinoceptor 1	Guanine nucleotide-binding protein alpha-1 subunit Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Mitogen-activated protein kinase HOG1 Putative meiotic phospholipase SPO1	P08539 P32485 P39105 P53541 Q03674 Q08108	CDC70 DAC1 GPA1 HOG1 PLB1 PLB2 PLB3 SCG1 SPO1 SSK3	Saccharomyces cerevisiae (brewer's yeast)

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