GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **250** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Calnexin/calreticulin cycle	Calnexin homolog Protein disulfide-isomerase	P17967 P27825	CNE1 MFP1 PDI1 TRG1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl aminopeptidase B	P18962	DAP2	Saccharomyces cerevisiae (brewer's yeast)
RHOU GTPase cycle	Actin cytoskeleton-regulatory complex protein END3 Actin cytoskeleton-regulatory complex protein PAN1 Cell division control protein 42 Class E vacuolar protein-sorting machinery protein HSE1 Clathrin heavy chain E3 ubiquitin-protein ligase RSP5 EH domain-containing and endocytosis protein 1 GTP-binding protein RHO5 Increased rDNA silencing protein 4 LAS seventeen-binding protein 1 Myosin-2 Myosin-4 Ras GTPase-activating-like protein IQG1 Serine/threonine-protein kinase CLA4 Serine/threonine-protein kinase SKM1 Serine/threonine-protein kinase STE20 tRNA (34-2'-O)-methyltransferase regulator RTT10	P19073 P19524 P22137 P32492 P32521 P34216 P36115 P38753 P39013 P39940 P48562 P53281 P53879 Q03497 Q08924 Q12280 Q12469	BUD15 CDC42 CDC66 CHC1 CLA4 CYK1 DIM2 EDE1 END3 ERE2 HSE1 IQG1 IRS4 LSB1 MDP1 MDP3 MIP3 MYO2 MYO4 NPI1 PAN1 RHO5 RSP5 RTT10 SHE1 SKM1 SRO2 STE20 TRM734	Saccharomyces cerevisiae (brewer's yeast)
Regulation of actin dynamics for phagocytic cup formation	Actin-like protein ARP9 Actin-related protein 2/3 complex subunit 1 Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 Serine/threonine-protein kinase STE20	P19073 P32381 P33204 P38328 P40518 P47117 P53731 Q03497 Q05123 Q05933	ACT2 ACT4 ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 ARP9 CDC42 SRO2 STE20 SWP59	Saccharomyces cerevisiae (brewer's yeast)
RHOQ GTPase cycle	Actin cytoskeleton-regulatory complex protein END3 Actin cytoskeleton-regulatory complex protein PAN1 Actin cytoskeleton-regulatory complex protein SLA1 Cell division control protein 42 E3 ubiquitin-protein ligase RSP5 EH domain-containing and endocytosis protein 1 GTP-binding protein RHO5 Increased rDNA silencing protein 4 Protein BZZ1 Protein ECM25 Protein transport protein SEC9 Putative zinc metalloprotease TRE2 Ras GTPase-activating-like protein IQG1 Serine/threonine-protein kinase CLA4 Serine/threonine-protein kinase SKM1 Serine/threonine-protein kinase STE20 Sporulation-specific protein 20 Uncharacterized protein TRE1 Vacuolar protein sorting-associated protein 70 Ypt/Rab-type GTPase YPT7	P19073 P32521 P32525 P32790 P32939 P34216 P36115 P38822 P39013 P39940 P40357 P47161 P48562 P53879 Q03497 Q04359 Q08693 Q08919 Q12280 Q12469	BUD15 BZZ1 CDC42 CLA4 CYK1 DIM2 ECM25 EDE1 END3 HSS7 IQG1 IRS4 LSB7 MDP1 MDP3 MIP3 NPI1 PAN1 RHO5 RSP5 SEC9 SKM1 SLA1 SPO20 SRO2 STE20 TRE1 TRE2 VAM4 VPS70 YPT7	Saccharomyces cerevisiae (brewer's yeast)
CD28 dependent Vav1 pathway	Cell division control protein 42 Serine/threonine-protein kinase CLA4 Serine/threonine-protein kinase SKM1 Serine/threonine-protein kinase STE20	P19073 P48562 Q03497 Q12469	CDC42 CLA4 SKM1 SRO2 STE20	Saccharomyces cerevisiae (brewer's yeast)
Metal ion SLC transporters	Copper transport protein CTR2 Vacuolar zinc transporter COT1 Vacuolar zinc transporter ZRC1	P20107 P32798 P38865	COT1 CTR2 ZRC1	Saccharomyces cerevisiae (brewer's yeast)
Fatty acyl-CoA biosynthesis	3-oxoacyl-[acyl-carrier-protein] reductase Acetyl-CoA carboxylase Acyl-CoA desaturase 1 Very long-chain fatty acid transport protein	P21147 P35731 P38225 Q00955	ABP2 ACC1 FAS3 FAT1 MTR7 OAR1 OLE1	Saccharomyces cerevisiae (brewer's yeast)
TNFR2 non-canonical NF-kB pathway	26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 homolog 26S proteasome regulatory subunit 8 homolog 26S proteasome regulatory subunit RPN12 26S proteasome regulatory subunit RPN1 26S proteasome regulatory subunit RPN2 26S proteasome regulatory subunit RPN3 26S proteasome regulatory subunit RPN5 26S proteasome regulatory subunit RPN6 26S proteasome regulatory subunit RPN7 26S proteasome regulatory subunit RPN8 26S proteasome regulatory subunit RPN9 26S proteasome subunit RPT4 Probable 26S proteasome regulatory subunit p27 Probable proteasome subunit alpha type-7 Proteasome activator BLM10 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-7 Serine/threonine-protein kinase BCK1/SLK1/SSP31 Ubiquitin carboxyl-terminal hydrolase RPN11	P21242 P21243 P22141 P23638 P23639 P25043 P25451 P30656 P30657 P32379 P32496 P32565 P33297 P33298 P33299 P38624 P38764 P40016 P40302 P40303 P40327 P40555 P43583 P43588 P53549 Q01389 Q01939 Q04062 Q06103 Q08723 Q12250 Q12377	BCK1 BLM10 BLM3 CIM3 CIM5 CRL13 CRL3 DOA3 DOA5 HRD2 LAS3 MPR1 NAS1 NAS2 NAS4 NAS5 NAS7 NIN1 PCS1 PRC1 PRC2 PRE1 PRE10 PRE2 PRE3 PRE4 PRE5 PRE6 PRE8 PRE9 PRG1 PRS1 PRS2 PRS4 PRS5 PUP1 PUP2 PUP3 RPD1 RPN1 RPN11 RPN12 RPN2 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 SCL1 SEN3 SLK1 SSP31 SUG1 SUG2 SUN2 TBPY TBY1 YHS4 YNT1 YTA1 YTA2 YTA3 YTA5	Saccharomyces cerevisiae (brewer's yeast)
Regulation of Apoptosis	Dynamin-like GTPase MGM1, mitochondrial Mitochondrial metalloendopeptidase OMA1 Vacuolar protein sorting-associated protein 1	P21576 P32266 P36163	LAM1 MDM17 MGM1 OMA1 SPO15 VPS1	Saccharomyces cerevisiae (brewer's yeast)
RHO GTPases Activate NADPH Oxidases	Bud emergence protein 1 Peptidyl-prolyl cis-trans isomerase ESS1 Phosphatidylinositol 3-kinase VPS34 Protein kinase C-like 1 Serine/threonine-protein kinase VPS15	P22219 P22543 P22696 P24583 P29366	BEM1 END12 ESS1 GRD8 HPO2 PEP15 PIN1 PKC1 PTF1 SRO1 STT1 VAC4 VPL19 VPL7 VPS15 VPS34 VPT29	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PIPs at the early endosome membrane	Phosphatidylinositol 3-kinase VPS34 Phosphatidylinositol 4-kinase LSB6 Phosphoinositide 3-phosphatase Serine/threonine-protein kinase VPS15	P22219 P22543 P42951 P47147	END12 GRD8 LSB6 PEP15 VAC4 VPL19 VPL7 VPS15 VPS34 VPT29 YMR1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PIPs at the late endosome membrane	Phosphatidylinositol 3-kinase VPS34 Phosphoinositide 3-phosphatase Serine/threonine-protein kinase VPS15	P22219 P22543 P47147	END12 GRD8 PEP15 VAC4 VPL19 VPL7 VPS15 VPS34 VPT29 YMR1	Saccharomyces cerevisiae (brewer's yeast)
PI5P Regulates TP53 Acetylation	Chromatin modification-related protein YNG2 Peptidyl-prolyl cis-trans isomerase ESS1 Phosphatidylinositol 4-phosphate 5-kinase MSS4 Protein YNG1 Transcriptional regulatory protein PHO23	P22696 P38806 P38994 P50947 Q08465	EAF4 ESS1 MSS4 NBN1 PHO23 PIN1 PTF1 YNG1 YNG2	Saccharomyces cerevisiae (brewer's yeast)
Lysosomal oligosaccharide catabolism	Alpha-mannosidase	P22855	AMS1	Saccharomyces cerevisiae (brewer's yeast)	G25577BM G28233ME G70323CJ
Glycogen synthesis	1,4-alpha-glucan-branching enzyme GLC7-interacting protein 2 GSY2-interacting protein PIG2 Glycogen [starch] synthase isoform 1 Glycogen [starch] synthase isoform 2 Glycogenin-1 Glycogenin-2 IME2-dependent-signaling protein Phosphoglucomutase 1 Phosphoglucomutase 2 Serine/threonine-protein phosphatase 1 regulatory subunit GAC1 Serine/threonine-protein phosphatase 1 regulatory subunit PIG1 UTP--glucose-1-phosphate uridylyltransferase	P23337 P27472 P28006 P32775 P32861 P33401 P36143 P37012 P40036 P40187 P46958 P47011 Q06216	GA-5 GAC1 GAL5 GIP2 GLC3 GLG1 GLG2 GSY1 GSY2 IDS2 PGM1 PGM2 PIG1 PIG2 UGP1	Saccharomyces cerevisiae (brewer's yeast)
Sphingolipid catabolism	Alkaline ceramidase YDC1 Diacylglycerol pyrophosphate phosphatase 1 Dihydrosphingosine 1-phosphate phosphatase LCB3 Dihydrosphingosine 1-phosphate phosphatase YSR3 Fatty aldehyde dehydrogenase HFD1 Lipid phosphate phosphatase 1 Sphingosine-1-phosphate lyase	P23501 P47013 Q02896 Q04396 Q04458 Q05521 Q05567	BST1 DPL1 DPP1 HFD1 LBP1 LBP2 LCB3 LPP1 YDC1 YSR2 YSR3 ZRG1	Saccharomyces cerevisiae (brewer's yeast)
Aspartate and asparagine metabolism	Asparagine synthetase [glutamine-hydrolyzing] 1 Asparagine synthetase [glutamine-hydrolyzing] 2 Aspartate aminotransferase, cytoplasmic Aspartate aminotransferase, mitochondrial Mitochondrial aspartate-glutamate transporter AGC1 Putative zinc metalloprotease TRE2 Uncharacterized protein TRE1 Vacuolar protein sorting-associated protein 70	P23542 P47161 P49089 P49090 Q01802 Q08693 Q08919 Q12482	AAT1 AAT2 AGC1 ASN1 ASN2 ASP5 TRE1 TRE2 VPS70	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of glycosylphosphatidylinositol (GPI)	GPI ethanolamine phosphate transferase 1 GPI ethanolamine phosphate transferase 2 GPI mannosyltransferase 2 GPI mannosyltransferase 3 GPI mannosyltransferase 4 GPI-anchored wall transfer protein 1 Glycosylphosphatidylinositol anchor biosynthesis protein 11 N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase	P23797 P30777 P36051 P38211 P40367 P47026 Q04174 Q06636	FSR2 GPI10 GPI11 GPI12 GPI18 GPI7 GWT1 LAS2 LAS21 MCD4 SAP2 SMP3 SSU21 ZRG16	Saccharomyces cerevisiae (brewer's yeast)
Switching of origins to a post-replicative state	DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Minichromosome maintenance protein 5	P24279 P29469 P29496 P30665 P38132 P53091	CDC46 CDC47 CDC54 HCD21 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7	Saccharomyces cerevisiae (brewer's yeast)
Assembly of the pre-replicative complex	DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Minichromosome maintenance protein 5	P24279 P29469 P29496 P30665 P38132 P53091	CDC46 CDC47 CDC54 HCD21 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7	Saccharomyces cerevisiae (brewer's yeast)
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 Protein kinase C-like 1	P24583 P32383	HPO2 PKC1 PLC1 STT1	Saccharomyces cerevisiae (brewer's yeast)
Response to elevated platelet cytosolic Ca2+	Protein kinase C-like 1	P24583	HPO2 PKC1 STT1	Saccharomyces cerevisiae (brewer's yeast)
Vitamin B2 (riboflavin) metabolism	Ectonucleotide pyrophosphatase/phosphodiesterase 1 Ectonucleotide pyrophosphatase/phosphodiesterase 2 Flavin adenine dinucleotide synthase Riboflavin kinase	P25353 P38913 P39997 Q03778	FAD1 FMN1 NPP1 NPP2	Saccharomyces cerevisiae (brewer's yeast)
Glycosphingolipid catabolism	Ectonucleotide pyrophosphatase/phosphodiesterase 1 Ectonucleotide pyrophosphatase/phosphodiesterase 2 Inositol phosphosphingolipids phospholipase C	P25353 P39997 P40015	ISC1 NPP1 NPP2	Saccharomyces cerevisiae (brewer's yeast)

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