GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **250** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
phospho-PLA2 pathway	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Putative meiotic phospholipase SPO1 Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P39105 P41808 P53541 Q00772 Q03674 Q08108	DAC2 FUS3 KSS1 MPK1 PLB1 PLB2 PLB3 SLT2 SMK1 SPO1	Saccharomyces cerevisiae (brewer's yeast)
ERKs are inactivated	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Protein phosphatase PP2A regulatory subunit A Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase PP2A-1 catalytic subunit Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P23594 P31383 P38903 P41808 Q00772	DAC2 FUS3 KSS1 MPK1 PPH21 RTS1 SCS1 SLT2 SMK1 TPD3	Saccharomyces cerevisiae (brewer's yeast)
Negative regulation of MAPK pathway	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Sporulation-specific mitogen-activated protein kinase SMK1 Tyrosine-protein phosphatase 1 Tyrosine-protein phosphatase 2 Tyrosine-protein phosphatase 3	P14681 P16892 P25044 P29461 P40048 P41808 Q00772	DAC2 FUS3 KSS1 MPK1 PTP1 PTP2 PTP3 SLT2 SMK1	Saccharomyces cerevisiae (brewer's yeast)
RAF/MAP kinase cascade	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P41808 Q00772	DAC2 FUS3 KSS1 MPK1 SLT2 SMK1	Saccharomyces cerevisiae (brewer's yeast)
RAF-independent MAPK1/3 activation	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P41808 Q00772	DAC2 FUS3 KSS1 MPK1 SLT2 SMK1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl aminopeptidase B	P18962	DAP2	Saccharomyces cerevisiae (brewer's yeast)
SUMOylation of transcription cofactors	ATP-dependent RNA helicase DBP2 Chromatin modification-related protein YNG2 Dual specificity protein kinase YAK1 Protein YNG1 SUMO-conjugating enzyme UBC9 Transcriptional regulatory protein PHO23 Ubiquitin-like protein SMT3	P14680 P24783 P38806 P50623 P50947 Q08465 Q12306	DBP2 EAF4 NBN1 PHO23 SMT3 UBC9 YAK1 YNG1 YNG2	Saccharomyces cerevisiae (brewer's yeast)
mRNA decay by 5' to 3' exoribonuclease	ATP-dependent RNA helicase DHH1 Deadenylation-dependent mRNA-decapping factor PAT1 Enhancer of mRNA-decapping protein 3 Sm-like protein LSm1 U6 snRNA-associated Sm-like protein LSm2 U6 snRNA-associated Sm-like protein LSm3 U6 snRNA-associated Sm-like protein LSm4 U6 snRNA-associated Sm-like protein LSm5 U6 snRNA-associated Sm-like protein LSm6 U6 snRNA-associated Sm-like protein LSm7 m7GpppN-mRNA hydrolase mRNA-decapping enzyme subunit 1	P25644 P38203 P39517 P39998 P40070 P40089 P47017 P53550 P53905 P57743 Q06406 Q12517	DCP1 DCP2 DHH1 EDC3 LSM1 LSM16 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MRT1 PAT1 PSU1 SDB23 SMX4 SMX5 SNP3 SPB8 USS1 USS2	Saccharomyces cerevisiae (brewer's yeast)
Triglyceride biosynthesis	Diacylglycerol O-acyltransferase 1 Glycerol kinase Phosphatidic acid phosphohydrolase 1	P32190 P32567 Q08650	DGA1 GUT1 PAH1 PAP1 SMP2	Saccharomyces cerevisiae (brewer's yeast)
Arachidonic acid metabolism	Diacylglycerol O-acyltransferase 1 Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Putative meiotic phospholipase SPO1	P39105 P53541 Q03674 Q08108 Q08650	DGA1 PLB1 PLB2 PLB3 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodeling of DAG and TAG	Diacylglycerol O-acyltransferase 1 Monoglyceride lipase	P28321 Q08650	DGA1 YJU3	Saccharomyces cerevisiae (brewer's yeast)
Wax biosynthesis	Diacylglycerol O-acyltransferase 1	Q08650	DGA1	Saccharomyces cerevisiae (brewer's yeast)
Apoptotic execution phase	Dynamin-related protein DNM1 Endoplasmic reticulum transmembrane protein 3 Serine/threonine-protein kinase KIC1	P38692 P54861 Q07451	DNM1 KIC1 NRK1 YET3	Saccharomyces cerevisiae (brewer's yeast)
HSF1-dependent transactivation	ATP-dependent molecular chaperone HSC82 ATP-dependent molecular chaperone HSP82 Heat shock protein SSA1 Heat shock protein SSA2 Heat shock protein SSA3 Heat shock protein SSA4 Heat shock transcription factor Ribosome-associated molecular chaperone SSB1 Ribosome-associated molecular chaperone SSB2 Serine/threonine-protein kinase TOR2 Target of rapamycin complex 1 subunit KOG1 Target of rapamycin complex subunit LST8	P02829 P09435 P10591 P10592 P10961 P11484 P15108 P22202 P32600 P38873 P40150 P41318	DRR2 HSC82 HSF1 HSP82 HSP90 KOG1 LAS24 LST8 SSA1 SSA2 SSA3 SSA4 SSB1 SSB2 TOR2 TSC14 YG101 YG103	Saccharomyces cerevisiae (brewer's yeast)
PI5P Regulates TP53 Acetylation	Chromatin modification-related protein YNG2 Peptidyl-prolyl cis-trans isomerase ESS1 Phosphatidylinositol 4-phosphate 5-kinase MSS4 Protein YNG1 Transcriptional regulatory protein PHO23	P22696 P38806 P38994 P50947 Q08465	EAF4 ESS1 MSS4 NBN1 PHO23 PIN1 PTF1 YNG1 YNG2	Saccharomyces cerevisiae (brewer's yeast)
Beta-oxidation of very long chain fatty acids	3,2-trans-enoyl-CoA isomerase 3-ketoacyl-CoA thiolase, peroxisomal Peroxisomal 2,4-dienoyl-CoA reductase SPS19 [(3E)-enoyl-CoA-producing] Peroxisomal acyl-coenzyme A thioester hydrolase 1 Peroxisomal long-chain fatty acid import protein 2	P27796 P32573 P41903 P41909 Q05871	ECI1 FOX3 PAL1 PAT2 POT1 POX3 PTE1 PXA1 SPS19 SPX19 SSH2 TES1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PIPs at the early endosome membrane	Phosphatidylinositol 3-kinase VPS34 Phosphatidylinositol 4-kinase LSB6 Phosphoinositide 3-phosphatase Serine/threonine-protein kinase VPS15	P22219 P22543 P42951 P47147	END12 GRD8 LSB6 PEP15 VAC4 VPL19 VPL7 VPS15 VPS34 VPT29 YMR1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PIPs at the late endosome membrane	Phosphatidylinositol 3-kinase VPS34 Phosphoinositide 3-phosphatase Serine/threonine-protein kinase VPS15	P22219 P22543 P47147	END12 GRD8 PEP15 VAC4 VPL19 VPL7 VPS15 VPS34 VPT29 YMR1	Saccharomyces cerevisiae (brewer's yeast)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 1 6-phosphogluconolactonase 3 Glucose-6-phosphate 1-dehydrogenase Phosphoribomutase Ribokinase Ribose-5-phosphate isomerase Ribulose-phosphate 3-epimerase Transaldolase	P11412 P15019 P25332 P38720 P38858 P46969 Q03262 Q12189	EPI1 GND1 MET19 PGM3 POS18 PRM15 RBK1 RKI1 RPE1 SOL3 TAL1 ZWF1	Saccharomyces cerevisiae (brewer's yeast)	G31080DL
Transport of bile salts and organic acids, metal ions and amine compounds	Ethionine resistance-conferring protein 1 Uncharacterized transporter YDR338C	P38767 Q05497	ERC1 YDR338C	Saccharomyces cerevisiae (brewer's yeast)
IRE1alpha activates chaperones	Serine/threonine-protein kinase/endoribonuclease IRE1	P32361	ERN1 IRE1	Saccharomyces cerevisiae (brewer's yeast)
Miscellaneous transport and binding events	Cystine transporter Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6 Mitochondrial inner membrane magnesium transporter MFM1 Vacuolar arginine/histidine antiporter YPQ2 Vacuolar histidine transporter YPQ3 Vacuolar lysine transporter YPQ1	P17261 P38279 P48439 Q02783 Q03723 Q06328 Q12010	ERS1 LPE10 MFM1 OST3 OST6 RTC2 YPQ1 YPQ2 YPQ3	Saccharomyces cerevisiae (brewer's yeast)
DNA Damage/Telomere Stress Induced Senescence	DNA repair protein RAD50 Double-strand break repair protein MRE11 Histone acetyltransferase ESA1 Serine/threonine-protein kinase TEL1	P12753 P32829 P38110 Q08649	ESA1 MRE11 RAD50 TEL1	Saccharomyces cerevisiae (brewer's yeast)
Sensing of DNA Double Strand Breaks	DNA repair protein RAD50 Double-strand break repair protein MRE11 Histone acetyltransferase ESA1 Serine/threonine-protein kinase TEL1	P12753 P32829 P38110 Q08649	ESA1 MRE11 RAD50 TEL1	Saccharomyces cerevisiae (brewer's yeast)
Transport of organic anions	Probable transporter MCH2 Probable transporter MCH4 Riboflavin transporter MCH5 Uncharacterized transporter ESBP6	P36032 P53918 Q08268 Q08777	ESBP6 MCH2 MCH3 MCH4 MCH5	Saccharomyces cerevisiae (brewer's yeast)

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