GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **228** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Inhibition of replication initiation of damaged DNA by RB1/E2F1	DNA polymerase alpha catalytic subunit A DNA polymerase alpha subunit B DNA primase large subunit DNA primase small subunit	P10363 P13382 P20457 P38121	CDC17 POL1 POL12 PRI1 PRI2	Saccharomyces cerevisiae (brewer's yeast)
Sphingolipid catabolism	Alkaline ceramidase YDC1 Diacylglycerol pyrophosphate phosphatase 1 Dihydrosphingosine 1-phosphate phosphatase LCB3 Dihydrosphingosine 1-phosphate phosphatase YSR3 Fatty aldehyde dehydrogenase HFD1 Lipid phosphate phosphatase 1 Sphingosine-1-phosphate lyase	P23501 P47013 Q02896 Q04396 Q04458 Q05521 Q05567	BST1 DPL1 DPP1 HFD1 LBP1 LBP2 LCB3 LPP1 YDC1 YSR2 YSR3 ZRG1	Saccharomyces cerevisiae (brewer's yeast)
Lysine catabolism	Aromatic amino acid aminotransferase 2 Aromatic/aminoadipate aminotransferase 1 Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] Uncharacterized protein YGL159W	P38840 P38999 P53090 P53110	ARO8 ARO9 LYS13 LYS9 YGL159W	Saccharomyces cerevisiae (brewer's yeast)
Amino acid transport across the plasma membrane	High-affinity methionine permease Low-affinity methionine permease Oligo-1,6-glucosidase IMA2 Oligo-1,6-glucosidase IMA3 Oligo-1,6-glucosidase IMA4 Probable transporter MCH2 Probable transporter MCH4 Riboflavin transporter MCH5 Uncharacterized transporter ESBP6 Vacuolar amino acid transporter 2 Vacuolar amino acid transporter 4	P0CW40 P0CW41 P36032 P38734 P39981 P50276 P50944 P53918 Q08268 Q08295 Q08777	AVT2 AVT4 ESBP6 FSP2 IMA2 IMA3 IMA4 MCH2 MCH3 MCH4 MCH5 MUP1 MUP3	Saccharomyces cerevisiae (brewer's yeast)
Processive synthesis on the lagging strand	DNA ligase 1 DNA polymerase alpha catalytic subunit A DNA polymerase alpha subunit B DNA polymerase delta catalytic subunit DNA polymerase delta small subunit DNA primase large subunit DNA primase small subunit Proliferating cell nuclear antigen	P04819 P10363 P13382 P15436 P15873 P20457 P38121 P46957	CDC17 CDC2 CDC9 HUS2 HYS2 POL1 POL12 POL3 POL30 POL31 PRI1 PRI2 SDP5 TEX1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Glutathione hydrolase proenzyme Leucine aminopeptidase 2 Oligomycin resistance ATP-dependent permease YOR1	P53049 Q05902 Q10740	CIS2 ECM38 LAP2 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
MAP2K and MAPK activation	MAP kinase kinase MKK1/SSP32 MAP kinase kinase MKK2/SSP33 MAP kinase kinase PBS2 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Serine/threonine-protein kinase STE7 Sporulation-specific mitogen-activated protein kinase SMK1	P06784 P08018 P14681 P16892 P32490 P32491 P41808 Q00772	DAC2 FUS3 HOG4 KSS1 MKK1 MKK2 MPK1 PBS2 SFS4 SLT2 SMK1 SSK4 SSP32 SSP33 STE7	Saccharomyces cerevisiae (brewer's yeast)
Clathrin-mediated endocytosis	AP-1 complex subunit beta-1 AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Actin cytoskeleton-regulatory complex protein END3 Actin cytoskeleton-regulatory complex protein PAN1 Clathrin heavy chain Clathrin light chain Cytokinesis protein 2 EH domain-containing and endocytosis protein 1 Increased rDNA silencing protein 4 Phosphatidylinositol 4-phosphate 5-kinase MSS4 Rho-GTPase-activating protein RGD2 Suppressor of yeast profilin deletion	P17891 P22137 P25623 P27351 P32521 P34216 P36000 P36115 P38065 P38994 P39013 P43556 Q00381 Q05080 Q99186	AMP1 APL1 APL2 APL3 APM4 APS2 BUD15 CHC1 CLC1 CYK2 DIM2 EDE1 END3 HOF1 IRS4 MDP3 MIP3 MSS4 PAN1 RGD2 SYP1 YAP17 YAP80	Saccharomyces cerevisiae (brewer's yeast)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Dipeptidyl aminopeptidase B	P18962	DAP2	Saccharomyces cerevisiae (brewer's yeast)
Recycling of bile acids and salts	ABC transporter ATP-binding protein/permease VMR1 ABC transporter NFT1 ATP-dependent bile acid permease Bile pigment transporter 1 Metal resistance protein YCF1 Oligomycin resistance ATP-dependent permease YOR1 Very long-chain fatty acid transport protein	P0CE68 P14772 P32386 P38225 P38735 P39109 P53049	BAT1 BPT1 FAT1 NFT1 VMR1 YBT1 YCF1 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
Glycerophospholipid biosynthesis	Mitochondrial import inner membrane translocase subunit TIM54 Sphingoid long chain base kinase 4 Sphingoid long chain base kinase 5	P47045 Q06147 Q12246	LCB4 LCB5 TIM54	Saccharomyces cerevisiae (brewer's yeast)
VLDLR internalisation and degradation	AP-1 complex subunit beta-1 AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Cerevisin Clathrin heavy chain Clathrin light chain Subtilase-type proteinase RRT12 Subtilisin-like protease 3	P09232 P17891 P22137 P25036 P25381 P27351 P36000 P38065 Q00381 Q99186	AMP1 APL1 APL2 APL3 APM4 APS2 CHC1 CLC1 OSW3 PRB1 RRT12 YAP17 YAP80 YSP3	Saccharomyces cerevisiae (brewer's yeast)
SUMOylation of transcription factors	DNA repair protein RAD9 E3 SUMO-protein ligase SIZ1 E3 SUMO-protein ligase SIZ2 Fork head protein homolog 1 Forkhead transcription factor HCM1 Retrograde regulation protein 3 SUMO-conjugating enzyme UBC9 Transcriptional regulator CRZ1 Ubiquitin-like protein SMT3	P14737 P25364 P38165 P40466 P50623 P53968 Q04195 Q12216 Q12306	CRZ1 FKH1 HAL8 HCM1 NFI1 RAD9 RTG3 SIZ1 SIZ2 SMT3 TCN1 UBC9 ULL1	Saccharomyces cerevisiae (brewer's yeast)
Regulation of actin dynamics for phagocytic cup formation	Actin-like protein ARP9 Actin-related protein 2/3 complex subunit 1 Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 Serine/threonine-protein kinase STE20	P19073 P32381 P33204 P38328 P40518 P47117 P53731 Q03497 Q05123 Q05933	ACT2 ACT4 ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 ARP9 CDC42 SRO2 STE20 SWP59	Saccharomyces cerevisiae (brewer's yeast)
RA biosynthesis pathway	Aldehyde dehydrogenase 5, mitochondrial D-arabinose dehydrogenase [NAD(P)+] heavy chain Magnesium-activated aldehyde dehydrogenase, cytosolic NADPH-dependent alpha-keto amide reductase Oxidoreductase-like protein SRL4 Potassium-activated aldehyde dehydrogenase, mitochondrial Probable oxidoreductase ENV9 S-(hydroxymethyl)glutathione dehydrogenase Uncharacterized oxidoreductase TDA5 Uncharacterized oxidoreductase YDL114W Uncharacterized oxidoreductase YJR096W Uncharacterized oxidoreductase YKL107W Uncharacterized oxidoreductase YNL181W	P32771 P34251 P38115 P40047 P46367 P47137 P53878 P54115 Q03085 Q06417 Q07530 Q07551 Q08651	ALD3 ALD4 ALD5 ALD6 ALD7 ALDH1 ALDH2 ALDH5 ARA1 ENV9 SFA SFA1 SRL4 TDA5 YDL114W YDL124W YJR096W YKL107W YNL181W	Saccharomyces cerevisiae (brewer's yeast)
APAP ADME	ABC transporter ATP-binding protein/permease VMR1 ABC transporter NFT1 ATP-dependent bile acid permease Bile pigment transporter 1 Cys-Gly metallodipeptidase DUG1 Glutathione hydrolase proenzyme Metal resistance protein YCF1 Oligomycin resistance ATP-dependent permease YOR1 Probable ATP-dependent permease	P0CE68 P14772 P25371 P32386 P38735 P39109 P43616 P53049 Q05902	ADP1 BAT1 BPT1 CIS2 DUG1 ECM38 NFT1 VMR1 YBT1 YCF1 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
Glycogen synthesis	1,4-alpha-glucan-branching enzyme GLC7-interacting protein 2 GSY2-interacting protein PIG2 Glycogen [starch] synthase isoform 1 Glycogen [starch] synthase isoform 2 Glycogenin-1 Glycogenin-2 IME2-dependent-signaling protein Phosphoglucomutase 1 Phosphoglucomutase 2 Serine/threonine-protein phosphatase 1 regulatory subunit GAC1 Serine/threonine-protein phosphatase 1 regulatory subunit PIG1 UTP--glucose-1-phosphate uridylyltransferase	P23337 P27472 P28006 P32775 P32861 P33401 P36143 P37012 P40036 P40187 P46958 P47011 Q06216	GA-5 GAC1 GAL5 GIP2 GLC3 GLG1 GLG2 GSY1 GSY2 IDS2 PGM1 PGM2 PIG1 PIG2 UGP1	Saccharomyces cerevisiae (brewer's yeast)
Cargo recognition for clathrin-mediated endocytosis	AP-1 complex subunit beta-1 AP-1 complex subunit mu-1-I AP-2 complex subunit alpha AP-2 complex subunit beta AP-2 complex subunit mu AP-2 complex subunit sigma Autophagy-related protein 27 EH domain-containing and endocytosis protein 1 Epsin-1 Epsin-2 Mannose 6-phosphate receptor-like protein 1 NEDD8-like protein RUB1 Ubiquitin domain-containing protein DSK2	P27351 P34216 P36000 P38065 P46989 P48510 Q00381 Q00776 Q03919 Q05785 Q06815 Q12518 Q99186	AMP1 APL1 APL2 APL3 APM1 APM4 APS2 ATG27 BUD15 DSK2 EDE1 ENT1 ENT2 ETF1 MRL1 RUB1 SHE4 YAP17 YAP54 YAP80	Saccharomyces cerevisiae (brewer's yeast)
Multifunctional anion exchangers	Sulfate permease 1 Sulfate permease 2	P38359 Q12325	SEL2 SFP2 SUL1 SUL2	Saccharomyces cerevisiae (brewer's yeast)
Regulation of insulin secretion	Probable metabolite transport protein YBR241C Vacuolar protein sorting-associated protein 73	P38142 P53142	VPS73 YBR241C	Saccharomyces cerevisiae (brewer's yeast)	G58161NS
RND1 GTPase cycle	Fatty aldehyde dehydrogenase HFD1 GTP-binding protein RHO1 GTP-binding protein RHO2 GTP-binding protein RHO3 GTP-binding protein RHO4 Heat shock protein STI1 Inhibitory regulator protein BUD2/CLA2 Inhibitory regulator protein IRA1 Inhibitory regulator protein IRA2 Putative zinc metalloprotease TRE2 Ras-like protein 2 Uncharacterized protein TRE1 Vacuolar protein sorting-associated protein 70 tRNA (34-2'-O)-methyltransferase regulator RTT10	P01120 P06780 P06781 P15705 P18963 P19158 P33314 P47161 Q00245 Q00246 Q04458 Q08693 Q08919 Q08924	ASC1 BUD2 CCS1 CLA2 CTN5 ERC25 ERE2 GLC1 GLC4 GLC5 HFD1 IRA1 IRA2 PPD1 RAS2 RHO1 RHO2 RHO3 RHO4 RTT10 STI1 TRE1 TRE2 TRM734 VPS70	Saccharomyces cerevisiae (brewer's yeast)
SUMOylation of SUMOylation proteins	E3 SUMO-protein ligase SIZ1 E3 SUMO-protein ligase SIZ2 Nucleoporin ASM4 Nucleoporin NDC1 Nucleoporin NIC96 Nucleoporin NSP1 Nucleoporin NUP116/NSP116 Nucleoporin NUP120 Nucleoporin NUP133 Nucleoporin NUP170 Nucleoporin NUP188 Nucleoporin NUP192 Nucleoporin NUP1 Nucleoporin NUP2 Nucleoporin NUP42 Nucleoporin NUP57 Nucleoporin NUP82 Nucleoporin NUP84 Nucleoporin NUP85 Nucleoporin SEH1 Protein MLP1 Protein transport protein SEC13 Ran-specific GTPase-activating protein 1 Ran-specific GTPase-activating protein 2 SUMO-conjugating enzyme UBC9 Ubiquitin-like protein SMT3 mRNA export factor GLE2	P14907 P20676 P32499 P32500 P34077 P35729 P36161 P38181 P40066 P40368 P40517 P41920 P46673 P47054 P48837 P49686 P50623 P52593 P52891 P53011 Q02455 Q02630 Q04195 Q04491 Q05166 Q12216 Q12306	ANU3 ASM4 CST20 GLE2 HTN1 MLP1 NDC1 NFI1 NIC96 NLE3 NSP1 NSP116 NUP1 NUP116 NUP120 NUP133 NUP170 NUP188 NUP192 NUP2 NUP42 NUP57 NUP59 NUP82 NUP84 NUP85 RAE1 RAT2 RAT3 RAT9 RIP1 SEC13 SEH1 SFO1 SIZ1 SIZ2 SMT3 UBC9 UIP1 ULL1 YRB1 YRB2	Saccharomyces cerevisiae (brewer's yeast)
Ub-specific processing proteases	26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 homolog 26S proteasome regulatory subunit 8 homolog 26S proteasome regulatory subunit RPN12 26S proteasome regulatory subunit RPN1 26S proteasome regulatory subunit RPN2 26S proteasome regulatory subunit RPN3 26S proteasome regulatory subunit RPN5 26S proteasome regulatory subunit RPN6 26S proteasome regulatory subunit RPN7 26S proteasome regulatory subunit RPN8 26S proteasome regulatory subunit RPN9 26S proteasome subunit RPT4 CAAX prenyl protease 2 Chromatin-remodeling complexes subunit NGG1 Histone H2A.1 Histone H2A.2 Histone H2B.1 Histone H2B.2 Histone acetyltransferase GCN5 M-phase inducer phosphatase Mediator of replication checkpoint protein 1 Polyubiquitin Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1 Probable proteasome subunit alpha type-7 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-7 SWIRM domain-containing protein FUN19 SWIRM domain-containing protein YOR338W Small ribosomal subunit protein eS1A Small ribosomal subunit protein eS1B Sorting nexin-3 Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 9 Transcription-associated protein 1 Transcriptional adapter 2 Transcriptional regulatory protein DEP1 Transcriptional regulatory protein SDS3 Ubiquitin carboxyl-terminal hydrolase 10 Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 3 Ubiquitin carboxyl-terminal hydrolase 6 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin carboxyl-terminal hydrolase RPN11 Y' element ATP-dependent helicase YEL077C Y' element ATP-dependent helicase YIL177C Y' element ATP-dependent helicase YJL225C Y' element ATP-dependent helicase YLL066C Y' element ATP-dependent helicase YLL067C Y' element ATP-dependent helicase YML133C Y' element ATP-dependent helicase YPR204W Y' element ATP-dependent helicase protein 1 copy 1 Y' element ATP-dependent helicase protein 1 copy 2 Y' element ATP-dependent helicase protein 1 copy 3 Y' element ATP-dependent helicase protein 1 copy 4 Y' element ATP-dependent helicase protein 1 copy 5 Y' element ATP-dependent helicase protein 1 copy 6 Y' element ATP-dependent helicase protein 1 copy 7 Y' element ATP-dependent helicase protein 1 copy 8	O13559 P02293 P02294 P04911 P04912 P0CG63 P0CX14 P0CX15 P0CX20 P0CX21 P0CX22 P21242 P21243 P22141 P23248 P23638 P23639 P23748 P25043 P25451 P25588 P28003 P30656 P30657 P31385 P32379 P32494 P32496 P32565 P33297 P33298 P33299 P33442 P38624 P38764 P38811 P40016 P40105 P40302 P40303 P40327 P40434 P40505 P40889 P43588 P43593 P50101 P50102 P53549 P53819 P53874 P53916 Q01476 Q01477 Q01939 Q02336 Q03099 Q03330 Q03530 Q04062 Q05027 Q06103 Q07888 Q08723 Q08826 Q08995 Q12030 Q12250 Q12377 Q3E7X8 Q99208 Q99326	ADA2 ADA3 ADA4 CIM3 CIM5 CRL13 CRL3 DEP1 DOA3 DOA5 DOT4 FUN19 FUN54 GCN5 GRD19 H2A1 H2A2 H2B1 H2B2 HRD2 HTA1 HTA2 HTB1 HTB2 MIH1 MPR1 MRC1 NAS1 NAS4 NAS5 NAS7 NGG1 NIN1 PCS1 PLC1 PLC2 PRC1 PRC2 PRE1 PRE10 PRE2 PRE3 PRE4 PRE5 PRE6 PRE8 PRE9 PRG1 PRS1 PRS2 PRS4 PRS5 PUP1 PUP2 PUP3 RCE1 RPD1 RPN1 RPN11 RPN12 RPN2 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPS10A RPS10B RPS1A RPS1B RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 SCD2 SCL1 SDS3 SEN3 SNX3 SPT11 SPT12 SUG1 SUG2 SUN2 SWI7 SWI9 TAF10 TAF17 TAF23 TAF25 TAF9 TBPY TBY1 TEP1 TRA1 UBI4 UBP10 UBP15 UBP2 UBP3 UBP6 UBP8 YEL077C YHS4 YIL177C YJL225C YLL066C YLL067C YML133C YNT1 YOR338W YPR204W YRF1-1 YRF1-2 YRF1-3 YRF1-4 YRF1-5 YRF1-6 YRF1-7 YRF1-8 YTA1 YTA2 YTA3 YTA5	Saccharomyces cerevisiae (brewer's yeast)
Transport of Mature mRNA derived from an Intron-Containing Transcript	ATP-dependent RNA helicase FAL1 Nonsense-mediated mRNA decay protein 3 Nuclear cap-binding protein complex subunit 1 Nuclear cap-binding protein subunit 2 Nucleoporin ASM4 Nucleoporin NDC1 Nucleoporin NIC96 Nucleoporin NSP1 Nucleoporin NUP116/NSP116 Nucleoporin NUP120 Nucleoporin NUP133 Nucleoporin NUP170 Nucleoporin NUP188 Nucleoporin NUP192 Nucleoporin NUP1 Nucleoporin NUP2 Nucleoporin NUP42 Nucleoporin NUP57 Nucleoporin NUP82 Nucleoporin NUP84 Nucleoporin NUP85 Nucleoporin SEH1 Protein MLP1 Protein transport protein SEC13 RNA annealing protein YRA1 Ran-specific GTPase-activating protein 1 Ran-specific GTPase-activating protein 2 Uncharacterized protein JIP4 mRNA export factor GLE1 mRNA export factor GLE2 mRNA export factor MEX67 mRNA transport regulator MTR2	P14907 P20676 P32499 P32500 P34077 P34160 P34232 P35729 P36161 P38181 P40066 P40368 P40517 P41920 P46673 P47054 P48412 P48837 P49686 P52593 P52891 P53011 Q02455 Q02630 Q03361 Q04491 Q05166 Q08920 Q12099 Q12159 Q12315 Q99257	ANU3 ASM4 BRR3 CBC1 CBC2 CBP20 CBP80 CST20 FAL1 GCR3 GLE1 GLE2 HTN1 JIP4 MEX67 MLP1 MTR2 MUD13 NDC1 NIC96 NLE3 NSP1 NSP116 NUP1 NUP116 NUP120 NUP133 NUP170 NUP188 NUP192 NUP2 NUP42 NUP57 NUP59 NUP82 NUP84 NUP85 RAE1 RAT2 RAT3 RAT9 RIP1 RSS1 SAE1 SEC13 SEH1 SFO1 STO1 SUA6 SUT1 UIP1 UPF3 YRA1 YRB1 YRB2	Saccharomyces cerevisiae (brewer's yeast)
Switching of origins to a post-replicative state	DNA replication licensing factor MCM2 DNA replication licensing factor MCM3 DNA replication licensing factor MCM4 DNA replication licensing factor MCM6 DNA replication licensing factor MCM7 Minichromosome maintenance protein 5	P24279 P29469 P29496 P30665 P38132 P53091	CDC46 CDC47 CDC54 HCD21 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7	Saccharomyces cerevisiae (brewer's yeast)

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