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Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits robust RNAi-mediated gene silencing.
Summary
- Title
- Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits robust RNAi-mediated gene silencing.
- Authors
-
- Nair JK
- Willoughby JL
- Chan A
- Charisse K
- Alam MR
- Wang Q
- Hoekstra M
- Kandasamy P
- Kel'in AV
- Milstein S
- Taneja N
- O'Shea J
- Shaikh S
- Zhang L
- van der Sluis RJ
- Jung ME
- Akinc A
- Hutabarat R
- Kuchimanchi S
- Fitzgerald K
- Zimmermann T
- van Berkel TJ
- Maier MA
- Rajeev KG
- Manoharan M
- Source
- J Am Chem Soc
- Publication Date
- 2014 Dec 10
- PubMed ID
- 25434769
