12374809

Summary
Title
Heparin and heparan sulfate disaccharides bind to the exchanger inhibitor peptide region of Na+/Ca2+ exchanger and reduce the cytosolic calcium of smooth muscle cell lines. Requirement of C4-C5 unsaturation and 1--> 4 glycosidic linkage for activity.
Authors
  • Shinjo SK
  • Tersariol IL
  • Oliveira V
  • Nakaie CR
  • Oshiro ME
  • Ferreira AT
  • Santos IA
  • Dietrich CP
  • Nader HB
Source
J Biol Chem
Publication Date
2002 Dec 13
PubMed ID
12374809

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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