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Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise.
Summary
- Title
- Analysis of PUGNAc and NAG-thiazoline as transition state analogues for human O-GlcNAcase: mechanistic and structural insights into inhibitor selectivity and transition state poise.
- Authors
-
- Whitworth GE
- Macauley MS
- Stubbs KA
- Dennis RJ
- Taylor EJ
- Davies GJ
- Greig IR
- Vocadlo DJ
- Source
- J Am Chem Soc
- Publication Date
- 2007 Jan 24
- PubMed ID
- 17227027
