25104357

Summary
Title
Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect.
Authors
  • Fan J
  • Kang HB
  • Shan C
  • Elf S
  • Lin R
  • Xie J
  • Gu TL
  • Aguiar M
  • Lonning S
  • Chung TW
  • Arellano M
  • Khoury HJ
  • Shin DM
  • Khuri FR
  • Boggon TJ
  • Kang S
  • Chen J
Source
J Biol Chem
Publication Date
2014 Sep 19
PubMed ID
25104357

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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