28726643

Summary
Title
Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases.
Authors
  • Castro-Fernandez V
  • Herrera-Morande A
  • Zamora R
  • Merino F
  • Gonzalez-Ordenes F
  • Padilla-Salinas F
  • Pereira HM
  • Brandão-Neto J
  • Garratt RC
  • Guixe V
Source
J Biol Chem
Publication Date
2017 Sep 22
PubMed ID
28726643

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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