|
Heterozygous p.Y955C mutation in DNA polymerase γ leads to alterations in bioenergetics, complex I subunit expression, and mtDNA replication.
|
- Rahman MM
- Young CKJ
- Goffart S
- Pohjoismäki JLO
- Young MJ
|
35760101
|
J Biol Chem
|
2022
|
|
Incorporation of fucose into glycans independent of the GDP-fucose transporter SLC35C1 preferentially utilizes salvaged over de novo GDP-fucose.
|
- Skurska E
- Szulc B
- Maszczak-Seneczko D
- Wiktor M
- Wiertelak W
- Makowiecka A
- Olczak M
|
35772493
|
J Biol Chem
|
2022
|
|
Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism.
|
- Tapio J
- Halmetoja R
- Dimova EY
- Mäki JM
- Laitala A
- Walkinshaw G
- Myllyharju J
- Serpi R
- Koivunen P
|
35787374
|
J Biol Chem
|
2022
|
|
A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2.
|
- Scoles DR
- Gandelman M
- Paul S
- Dexheimer T
- Dansithong W
- Figueroa KP
- Pflieger LT
- Redlin S
- Kales SC
- Sun H
- Maloney D
- Damoiseaux R
- Henderson MJ
- Simeonov A
- Jadhav A
- Pulst SM
|
35787375
|
J Biol Chem
|
2022
|
|
β-Cells retain a pool of insulin-containing secretory vesicles regulated by adherens junctions and the cadherin-binding protein p120 catenin.
|
- Dissanayake WC
- Shepherd PR
|
35809641
|
J Biol Chem
|
2022
|
|
Activation of the canonical ER stress IRE1-XBP1 pathway by insulin regulates glucose and lipid metabolism.
|
- Peng J
- Qin C
- Ramatchandirin B
- Pearah A
- Guo S
- Hussain M
- Yu L
- Wondisford FE
- He L
|
35863429
|
J Biol Chem
|
2022
|
|
Hepatic p53 is regulated by transcription factor FOXO1 and acutely controls glycogen homeostasis.
|
- Oster M
- Galhuber M
- Krstic J
- Steinhoff JS
- Lenihan-Geels G
- Wulff S
- Kiefer MF
- Petricek KM
- Wowro SJ
- Flores RE
- Yang N
- Li C
- Meng Y
- Reinisch I
- Sommerfeld M
- Weger S
- Habisch H
- Madl T
- Schulz TJ
- Prokesch A
- Schupp M
|
35868560
|
J Biol Chem
|
2022
|
|
Vitamin B3, nicotinamide, enhances mitochondrial metabolism to promote differentiation of the retinal pigment epithelium.
|
- Hazim RA
- Paniagua AE
- Tang L
- Yang K
- Kim KKO
- Stiles L
- Divakaruni AS
- Williams DS
|
35868562
|
J Biol Chem
|
2022
|
|
Unusual β1-4-galactosidase activity of an α1-6-mannosidase from Xanthomonas manihotis in the processing of branched hybrid and complex glycans.
|
- She YM
- Klupt K
- Hatfield G
- Jia Z
- Tam RY
|
35921895
|
J Biol Chem
|
2022
|
|
Protein arginine methyltransferase PRMT1 promotes adipogenesis by modulating transcription factors C/EBPβ and PPARγ.
|
- Zhu Q
- Wang D
- Liang F
- Tong X
- Liang Z
- Wang X
- Chen Y
- Mo D
|
35921899
|
J Biol Chem
|
2022
|
|
Chlamydia trachomatis development requires both host glycolysis and oxidative phosphorylation but has only minor effects on these pathways.
|
- N'Gadjaga MD
- Perrinet S
- Connor MG
- Bertolin G
- Millot GA
- Subtil A
|
35931114
|
J Biol Chem
|
2022
|
|
An immunogenic cell injury module for the single-cell multiplexed activity metabolomics platform to identify promising anti-cancer natural products.
|
- Balsamo JA
- Penton KE
- Zhao Z
- Hayes MJ
- Lima SM
- Irish JM
- Bachmann BO
|
35931117
|
J Biol Chem
|
2022
|
|
Biased GPCR signaling by the native parathyroid hormone-related protein 1 to 141 relative to its N-terminal fragment 1 to 36.
|
- Peña KA
- White AD
- Savransky S
- Castillo IP
- Jean-Alphonse FG
- Gardella TJ
- Sutkeviciute I
- Vilardaga JP
|
35933010
|
J Biol Chem
|
2022
|
|
Human CIDEC transgene improves lipid metabolism and protects against high-fat diet-induced glucose intolerance in mice.
|
- Gupta A
- Balakrishnan B
- Karki S
- Slayton M
- Jash S
- Banerjee S
- Grahn THM
- Jambunathan S
- Disney S
- Hussein H
- Kong D
- Lowell BB
- Natarajan P
- Reddy UK
- Gokce N
- Sharma VM
- Puri V
|
35963433
|
J Biol Chem
|
2022
|
|
Phosphatidic acid inhibits inositol synthesis by inducing nuclear translocation of kinase IP6K1 and repression of myo-inositol-3-P synthase.
|
- Lazcano P
- Schmidtke MW
- Onu CJ
- Greenberg ML
|
35963434
|
J Biol Chem
|
2022
|
|
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
|
- Xu X
- Arunagiri A
- Haataja L
- Alam M
- Ji S
- Qi L
- Tsai B
- Liu M
- Arvan P
|
35988641
|
J Biol Chem
|
2022
|
|
N-glycosylation modulates enzymatic activity of Trypanosoma congolense trans-sialidase.
|
- Rosenau J
- Grothaus IL
- Yang Y
- Kumar ND
- Ciacchi LC
- Kelm S
- Waespy M
|
35995210
|
J Biol Chem
|
2022
|
|
G protein-coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin.
|
- Varney MJ
- Steyaert W
- Coucke PJ
- Delanghe JR
- Uehling DE
- Joseph B
- Marcellus R
- Al-Awar R
- Benovic JL
|
36030052
|
J Biol Chem
|
2022
|
|
Multi-OMICs analysis reveals metabolic and epigenetic changes associated with macrophage polarization.
|
- Sowers ML
- Tang H
- Singh VK
- Khan A
- Mishra A
- Restrepo BI
- Jagannath C
- Zhang K
|
36030823
|
J Biol Chem
|
2022
|
|
GC × GC-TOFMS metabolomics analysis identifies elevated levels of plasma sugars and sugar alcohols in diabetic mellitus patients with kidney failure.
|
- Duangkumpha K
- Jariyasopit N
- Wanichthanarak K
- Dhakal E
- Wisanpitayakorn P
- Thotsiri S
- Sirivatanauksorn Y
- Kitiyakara C
- Sathirapongsasuti N
- Khoomrung S
|
36055403
|
J Biol Chem
|
2022
|
|
Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
|
- Johnson DA
- Piper IM
- Vogel BA
- Jackson SN
- Svendsen JE
- Kodama HM
- Lee DE
- Lindblom KM
- McCarty J
- Antos JM
- Amacher JF
|
36055407
|
J Biol Chem
|
2022
|
|
A defect in cell wall recycling confers antibiotic resistance and sensitivity in Staphylococcus aureus.
|
|
36089064
|
J Biol Chem
|
2022
|
|
Sequential in vitro enzymatic N-glycoprotein modification reveals site-specific rates of glycoenzyme processing.
|
- Adams TM
- Zhao P
- Chapla D
- Moremen KW
- Wells L
|
36089065
|
J Biol Chem
|
2022
|
|
Molecular characterization of the type VI secretion system effector Tlde1a reveals a structurally altered LD-transpeptidase fold.
|
- Lorente Cobo N
- Sibinelli-Sousa S
- Biboy J
- Vollmer W
- Bayer-Santos E
- Prehna G
|
36183829
|
J Biol Chem
|
2022
|
|
Aurora A-mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression.
|
- Jiang Y
- Wang T
- Sheng D
- Han C
- Xu T
- Zhang P
- You W
- Fan W
- Zhang Z
- Jin T
- Duan X
- Yuan X
- Liu X
- Zhang K
- Ruan K
- Shi J
- Guo J
- Cheng A
- Yang Z
|
36198360
|
J Biol Chem
|
2022
|
GlyCosmos PubAnnotations
