POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.
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Retinoic acid exerts sexually dimorphic effects on muscle energy metabolism and function.
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Glucose-mediated de novo lipogenesis in photoreceptors drives early diabetic retinopathy.
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2021
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Valproate activates the Snf1 kinase in Saccharomyces cerevisiae by decreasing the cytosolic pH.
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J Biol Chem
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2021
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Metabolic flexibility maintains proliferation and migration of FGFR signaling-deficient lymphatic endothelial cells.
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J Biol Chem
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2021
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In silico and in vitro analysis of an Aspergillus niger chitin deacetylase to decipher its subsite sugar preferences.
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J Biol Chem
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2021
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The essential glucose transporter GLUT1 is epigenetically upregulated by C/EBPβ and WT1 during decidualization of the endometrium.
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J Biol Chem
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2021
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Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin.
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J Biol Chem
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2021
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The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy.
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34520759
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J Biol Chem
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2021
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Dynamin-related protein 1 regulates substrate oxidation in skeletal muscle by stabilizing cellular and mitochondrial calcium dynamics.
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J Biol Chem
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2021
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Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells.
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J Biol Chem
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2021
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Mice lacking the proton channel Hv1 exhibit sex-specific differences in glucose homeostasis.
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34547291
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J Biol Chem
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2021
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Sphingadienine-1-phosphate levels are regulated by a novel glycoside hydrolase family 1 glucocerebrosidase widely distributed in seed plants.
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2021
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GPNMB plays a protective role against obesity-related metabolic disorders by reducing macrophage inflammatory capacity.
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J Biol Chem
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Sex hormones regulate metainflammation in diet-induced obesity in mice.
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Molecular dynamics simulations elucidate oligosaccharide recognition pathways by galectin-3 at atomic resolution.
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J Biol Chem
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2021
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The cell surface hyaluronidase TMEM2 is essential for systemic hyaluronan catabolism and turnover.
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J Biol Chem
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2021
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The sialidase NEU1 directly interacts with the juxtamembranous segment of the cytoplasmic domain of mucin-1 to inhibit downstream PI3K-Akt signaling.
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J Biol Chem
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2021
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A novel C-type lectin activates the complement cascade in the primitive oyster Crassostrea gigas.
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J Biol Chem
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2021
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Structure of a bacterial α-1,2-glucosidase defines mechanisms of hydrolysis and substrate specificity in GH65 family hydrolases.
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34728215
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J Biol Chem
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2021
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Hydrophobicity-tuned anion responsiveness underlies endosomolytic cargo delivery mediated by amphipathic vehicle peptides.
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34736897
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J Biol Chem
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2021
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GRP75 mediates endoplasmic reticulum-mitochondria coupling during palmitate-induced pancreatic β-cell apoptosis.
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J Biol Chem
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2021
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Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show reduced inner fluidity.
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J Biol Chem
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2021
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Binding with heat shock cognate protein HSC70 fine-tunes the Golgi association of the small GTPase ARL5B.
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J Biol Chem
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2021
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Malonyl-acyl carrier protein decarboxylase activity promotes fatty acid and cell envelope biosynthesis in Proteobacteria.
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34801557
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J Biol Chem
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2021
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