Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
rheumatic heart disease
Summary
- Synonym
-
- rheumatic carditis
- Definition
- A heart valve disease that is characterized by repeated inflammation with fibrinous repair caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords.
- Super Class
- heart valve disease
External Links
- Disease Ontology
- DOID:0050827
- Mondo Disease Ontology
- MeSH
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 59 | ACTA2 | actin alpha 2, smooth muscle | |
| 581 | BAX | BCL2 associated X, apoptosis regulator | |
| 948 | CD36 | CD36 molecule (CD36 blood group) | |
| 1277 | COL1A1 | collagen type I alpha 1 chain | |
| 1281 | COL3A1 | collagen type III alpha 1 chain | |
| 2597 | GAPDH | glyceraldehyde-3-phosphate dehydrogenase | |
| 3117 | HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | |
| 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | |
| 3123 | HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | |
| 3586 | IL10 | interleukin 10 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11475 | Acta2 | actin alpha 2, smooth muscle, aorta | |
| 12028 | Bax | BCL2-associated X protein | |
| 12491 | Cd36 | CD36 molecule | |
| 12825 | Col3a1 | collagen, type III, alpha 1 | |
| 12842 | Col1a1 | collagen, type I, alpha 1 | |
| 14433 | Gapdh | glyceraldehyde-3-phosphate dehydrogenase | |
| 14960 | H2-Aa | histocompatibility 2, class II antigen A, alpha | |
| 14961 | H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | |
| 14969 | H2-Eb1 | histocompatibility 2, class II antigen E beta | |
| 16323 | Inhba | inhibin beta-A |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 174578 | gpd-4 | Glyceraldehyde-3-phosphate dehydrogenase 4 | |
| 174603 | gpd-1 | Glyceraldehyde-3-phosphate dehydrogenase 1 | |
| 176673 | scav-3 | Sensory neuron membrane protein 2 | |
| 176787 | scav-2 | SCAVenger receptor (CD36 family) related | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180601 | gpd-3 | Glyceraldehyde-3-phosphate dehydrogenase 3 |
