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rheumatic heart disease
Summary
- Synonym
-
- rheumatic carditis
- Definition
- A heart valve disease that is characterized by repeated inflammation with fibrinous repair caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords.
- Super Class
- heart valve disease
External Links
- Disease Ontology
- DOID:0050827
- Mondo Disease Ontology
- MeSH
Related Genes
