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atypical chronic myeloid leukemia, BCR-ABL1 negative
Summary
- Synonym
-
- aCML
- atypical CML
- atypical chronic myeloid leukaemia
- atypical chronic myeloid leukaemia BCR-ABL1 negative
- atypical chronic myeloid leukemia BCR-ABL1 negative
- subacute myeloid leukemia
- Definition
- A myelodysplastic myeloproliferative neoplasm characterized by the principal involvement of the neutrophil series with leukocytosis and multilineage dysplasia. The neoplastic cells do not have a Philadelphia chromosome or the BCR/ABL fusion gene.
- Super Class
- myelodysplastic/myeloproliferative neoplasm
External Links
- Disease Ontology
- DOID:0060597
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- ORDO
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 5728 | PTEN | phosphatase and tensin homolog | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 | |
| 7412 | VCAM1 | vascular cell adhesion molecule 1 | |
| 8809 | IL18R1 | interleukin 18 receptor 1 | |
| 9126 | SMC3 | structural maintenance of chromosomes 3 | |
| 9215 | LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | |
| 10682 | EBP | EBP cholestenol delta-isomerase | |
| 22914 | KLRK1 | killer cell lectin like receptor K1 | |
| 27036 | SIGLEC7 | sialic acid binding Ig like lectin 7 | |
| 27306 | HPGDS | hematopoietic prostaglandin D synthase |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9Y286 | Sialic acid-binding Ig-like lectin 7 |
