abdominal obesity-metabolic syndrome

Summary
Definition
A syndrome that is characterized by abdominal obesity, blood lipid disorders, inflammation, insulin resistance or full-blown diabetes, and increased risk of developing cardiovascular disease.
Super Class
autosomal dominant disease syndrome
Disease Ontology
DOID:0060611
Mondo Disease Ontology
MeSH
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying all 9 entries
Gene ID Gene Symbol Description Source
1655 DDX5 DEAD-box helicase 5
2984 GUCY2C guanylate cyclase 2C
3952 LEP leptin
5468 PPARG peroxisome proliferator activated receptor gamma
10521 DDX17 DEAD-box helicase 17
10891 PPARGC1A PPARG coactivator 1 alpha
23410 SIRT3 sirtuin 3
56606 SLC2A9 solute carrier family 2 member 9
79661 NEIL1 nei like DNA glycosylase 1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
14917 Gucy2c guanylate cyclase 2c
16846 Lep leptin
18759 Prkci protein kinase C, iota
19016 Pparg peroxisome proliferator activated receptor gamma
19017 Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
72774 Neil1 nei endonuclease VIII-like 1 (E. coli)
117591 Slc2a9 solute carrier family 2 (facilitated glucose transporter), member 9
Displaying all 4 entries
Gene ID Gene Symbol Description Source
25608 Lep leptin
25664 Pparg peroxisome proliferator-activated receptor gamma
25711 Gucy2c guanylate cyclase 2C
83516 Ppargc1a PPARG coactivator 1 alpha
Displaying 1 entry
Gene ID Gene Symbol Description Source
191654 gcy-27 Receptor-type guanylate cyclase gcy-27
Displaying 1 entry
Gene ID Gene Symbol Description Source
852543 VVS1 Vvs1p

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024