Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Parkinson's disease 4
Summary
- Synonym
-
- autosomal dominant Lewy body Parkinson disease 4
- autosomal dominant Parkinson disease 4
- autosomal dominant Parkinson's disease 4
- Definition
- A late onset Parkinson disease that has_material_basis_in heterozygous triplication of the alpha-synuclein gene on chromosome 4q22.
- Super Class
- autosomal dominant disease late onset Parkinson's disease
External Links
- Disease Ontology
- DOID:0060895
- Mondo Disease Ontology
- OMIM
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 9197 | SLC33A1 | solute carrier family 33 member 1 | |
| 9365 | KL | klotho | |
| 9536 | PTGES | prostaglandin E synthase | |
| 10159 | ATP6AP2 | ATPase H+ transporting accessory protein 2 | |
| 10327 | AKR1A1 | aldo-keto reductase family 1 member A1 | |
| 10457 | GPNMB | glycoprotein nmb | |
| 10724 | OGA | O-GlcNAcase | |
| 10728 | PTGES3 | prostaglandin E synthase 3 | |
| 10908 | PNPLA6 | patatin like phospholipase domain containing 6 | |
| 11332 | ACOT7 | acyl-CoA thioesterase 7 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q13231 | Chitotriosidase-1 | |
| Q13393 | Phospholipase D1 | |
| Q13510 | Acid ceramidase | |
| Q14956 | Transmembrane glycoprotein NMB | |
| Q15185 | Prostaglandin E synthase 3 | |
| Q16678 | Cytochrome P450 1B1 | |
| Q16760 | Diacylglycerol kinase delta | |
| Q6P1J6 | Phospholipase B1, membrane-associated | |
| Q6SZW1 | NAD(+) hydrolase SARM1 | |
| Q6UWN5 | Ly6/PLAUR domain-containing protein 5 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001824 | Weight loss |
| HP:0002015 | Dysphagia |
| HP:0002063 | Rigidity |
| HP:0002067 | Bradykinesia |
| HP:0002120 | Cerebral cortical atrophy |
| HP:0002171 | Gliosis |
| HP:0002172 | Postural instability |
| HP:0002304 | Akinesia |
| HP:0002322 | Resting tremor |
| HP:0002359 | Frequent falls |
