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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
developmental and epileptic encephalopathy 21
Summary
- Synonym
-
- DEE21
- early infantile epileptic encephalopathy 21
- Definition
- A developmental and epileptic encephalopathy characterized by onset in the first months of life by intractable seizures and severely impaired psychomotor development that has_material_basis_in homozygous or compound heterozygous mutation in the NECAP1 gene on chromosome 12p13.
- Super Class
- autosomal recessive disease developmental and epileptic encephalopathy
External Links
- Disease Ontology
- DOID:0080443
- Mondo Disease Ontology
- OMIM
Related Genes
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9NY47 | Voltage-dependent calcium channel subunit alpha-2/delta-2 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001290 | Generalized hypotonia |
| HP:0001298 | Encephalopathy |
| HP:0001315 | Reduced tendon reflexes |
| HP:0001336 | Myoclonus |
| HP:0001337 | Tremor |
| HP:0001508 | Failure to thrive |
| HP:0001558 | Decreased fetal movement |
| HP:0002020 | Gastroesophageal reflux |
| HP:0002059 | Cerebral atrophy |
| HP:0002063 | Rigidity |
