multicentric Castleman disease

Summary
Synonym
  • MCD
  • PMCD
  • multicentric giant lymph node hyperplasia
  • plasmablastic multicentric Castleman disease
Definition
A Castleman disease characterized by systemic inflammatory symptoms, polyclonal lymphoproliferation, cytopenias, and multiple organ system dysfunction caused by a cytokine storm often including interleukin-6.
Super Class
Castleman disease
External Links
Disease Ontology
DOID:0111152
MeSH
UMLS
NCI Thesaurus
ORDO
GARD
Related Genes
Displaying all 8 entries
Gene ID Gene Symbol Description Source
952 CD38 CD38 molecule
4684 NCAM1 neural cell adhesion molecule 1
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
5291 PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
5293 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
5294 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
10682 EBP EBP cholestenol delta-isomerase
23417 MLYCD malonyl-CoA decarboxylase

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024