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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Neural cell adhesion molecule 1
Summary
- UniProt ID
- P13591
- Gene Symbol
-
- NCAM1
- NCAM
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011515
- GlyConnect
- GlyGen
- P13591
- PubChem
- P13591
- RaftProt
- P13591
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell adhesion
- Cell membrane
- Disulfide bond
- GPI-anchor
- Host cell receptor for virus entry
- Host-virus interaction
- Immunoglobulin domain
- Phosphoprotein
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| epithelial to mesenchymal transition |
| cell adhesion |
| regulation of semaphorin-plexin signaling pathway |
| commissural neuron axon guidance |
| GO Term |
|---|
| Golgi membrane |
| extracellular region |
| plasma membrane |
| membrane |
| collagen-containing extracellular matrix |
| cytosol |
| external side of plasma membrane |
| cell surface |
| GO Term |
|---|
| virus receptor activity |
Sequence
MLQTKDLIWTLFFLGTAVSLQVDIVPSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQVEPYSSTAQVQFDEPEATGGVPILKYKAEWRAVGEEVWHSKWYDAKEASMEGIVTIVGLKPETTYAVRLAALNGKGLGEISAASEFKTQPVQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVRYRALSSEWKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQPTAIPANGSPTSGLSTGAIVGILIVIFVLLLVVVDITCYFLNKCGLFMCIAVNLCGKAGPGAKGKDMEEGKAAFSKDESKEPIVEVRTEEERTPNHDGGKHTEPNETTPLTEPEKGPVEAKPECQETETKPAPAEVKTVPNDATQTKENESKA
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 122 |
|
|||
| 125 |
|
|||
| 222 | N-linked (GlcNAc...) asparagine |
|
||
| 315 | N-linked (GlcNAc...) asparagine |
|
||
| 347 | N-linked (GlcNAc...) asparagine | |||
| 433 | N-linked (GlcNAc...) asparagine |
|
||
| 459 | N-linked (GlcNAc...) asparagine | |||
| 488 | N-linked (GlcNAc...) asparagine |
G57321FI
G16125XL
G30769VJ
G68490OW
G80479JV
G07246CJ
G10819WX
G43223CG
G60177UT
G82830MN
G08918WF
G70441OD
G80223IX
G25418HZ
G27058EU
G41071NU
G91636VS
G06356OH
G59626AS
G10486CT
G50045TK
G95865ZB
G31852PQ
G67031OU
G11314AS
G43669FQ
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| ECM proteoglycans | Homo sapiens |
| Interferon gamma signaling | Homo sapiens |
| NCAM signaling for neurite out-growth | Homo sapiens |
| NCAM1 interactions | Homo sapiens |
| RAF/MAP kinase cascade | Homo sapiens |
| Signal transduction by L1 | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3571 | liver cancer | |
| DOID:0050012 | chikungunya | |
| DOID:0050120 | hemophagocytic lymphohistiocytosis | |
| DOID:0050328 | congenital hypothyroidism | |
| DOID:0050523 | adult T-cell leukemia/lymphoma | |
| DOID:0050580 | hereditary lymphedema | |
| DOID:0050589 | inflammatory bowel disease | |
| DOID:0050590 | severe congenital neutropenia | |
| DOID:0050635 | alternating hemiplegia of childhood | |
| DOID:0050741 | alcohol dependence |
