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Standards Ontologies Notations
alcohol dependence

Summary
Synonym
  • alcoholism
Definition
A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol.
Super Class
substance dependence
Disease Ontology
DOID:0050741
Mondo Disease Ontology
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 72 in total
Gene ID Gene Symbol Description Source
125 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
126 ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
127 ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
150 ADRA2A adrenoceptor alpha 2A
196 AHR aryl hydrocarbon receptor
217 ALDH2 aldehyde dehydrogenase 2 family member
284 ANGPT1 angiopoietin 1
367 AR androgen receptor
406 BMAL1 basic helix-loop-helix ARNT like 1
627 BDNF brain derived neurotrophic factor
Displaying entries 1 - 10 of 52 in total
Gene ID Gene Symbol Description Source
11522 Adh1 alcohol dehydrogenase 1 (class I)
11551 Adra2a adrenergic receptor, alpha 2a
11600 Angpt1 angiopoietin 1
11669 Aldh2 aldehyde dehydrogenase 2, mitochondrial
12064 Bdnf brain derived neurotrophic factor
12288 Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit
12846 Comt catechol-O-methyltransferase
12876 Cpe carboxypeptidase E
13095 Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29
13488 Drd1 dopamine receptor D1
Displaying entries 1 - 10 of 39 in total
Gene ID Gene Symbol Description Source
24225 Bdnf brain-derived neurotrophic factor
24239 Cacna1c calcium voltage-gated channel subunit alpha1 C
24267 Comt catechol-O-methyltransferase
24318 Drd2 dopamine receptor D2
24409 Grin2a glutamate ionotropic receptor NMDA type subunit 2A
24473 Htr1a 5-hydroxytryptamine receptor 1A
24586 Ncam1 neural cell adhesion molecule 1
24596 Ngfr nerve growth factor receptor
24613 Oprd1 opioid receptor, delta 1
24922 Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
31251 per period
31309 dnc dunce
31364 Fas2 Fasciclin 2
32554 Lcch3 Ligand-gated chloride channel homolog 3
32674 RSG7 Regulator of G-protein signaling 7
33007 Dop2R Dopamine 2-like receptor
34950 Ca-alpha1D Ca[2+]-channel protein alpha[[1]] subunit D
36411 sca scabrous
36849 DAT Dopamine transporter
37191 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B
Displaying all 4 entries
Gene ID Gene Symbol Description Source
58133 ngfb nerve growth factor b (beta polypeptide)
170581 cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit
561372 comta catechol-O-methyltransferase a
565370 comtb catechol-O-methyltransferase b
Displaying all 10 entries
Gene ID Gene Symbol Description Source Organism
373802 pomc.S proopiomelanocortin S homeolog Xenopus laevis (African clawed frog)
378584 drd2.L dopamine receptor D2 L homeolog Xenopus laevis (African clawed frog)
378605 htr1a.L 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog Xenopus laevis (African clawed frog)
380532 pomc.L proopiomelanocortin L homeolog Xenopus laevis (African clawed frog)
397761 ncam1.S neural cell adhesion molecule 1 S homeolog Xenopus laevis (African clawed frog)
397762 ncam1.L neural cell adhesion molecule 1 L homeolog Xenopus laevis (African clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
100127346 grin2a.L glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog Xenopus laevis (African clawed frog)
100488055 cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit Xenopus tropicalis (tropical clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 1 - 10 of 21 in total
Gene ID Gene Symbol Description Source
171619 C53D5.5 Gamma-glutamyltranspeptidase 1
172105 unc-38 Acetylcholine receptor subunit alpha-type unc-38
172150 unc-63 Acetylcholine receptor subunit alpha-type unc-63
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
176304 dat-1 Sodium-dependent dopamine transporter
176691 gab-1 Gamma-aminobutyric acid receptor subunit beta
177911 Y43C5A.2 Fibrinogen C-terminal domain-containing protein
177940 egl-21 Carboxypeptidase E
178269 lev-1 Acetylcholine receptor subunit beta-type lev-1
179347 dop-2 Dopamine receptor 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
851006 ECM38 gamma-glutamyltransferase
The Human Phenotype Ontology
Displaying 1 entry
HPO ID HPO Term
HP:0001426 Non-Mendelian inheritance
Displaying all 2 entries
Gene ID Gene Symbol Description
125 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
126 ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024