Glial cell line-derived neurotrophic factor

Summary
UniProt ID
Q07731
Gene Symbol
  • Gdnf
Gene ID
25453
Organism
Rattus norvegicus (Norway rat)
PubChem
Q07731
Re-Glyco
Q07731
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cleavage on pair of basic residues
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Growth factor
  • Reference proteome
  • Secreted
  • Signal
Gene Ontology (GO)
Sequence
MKLWDVVAVCLVLLHTASAFPLPAGKRLLEAPAEDHSLGHRRVPFALTSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQAAALPRRERNRQAAAASPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCEAAETMYDKILKNLSRSRRLTSDKVGQACCRPVAFDDDLSFLDDSLVYHILRKHSAKRCGCI
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
126 N-linked (GlcNAc...) asparagine
162 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
RAF/MAP kinase cascade Rattus norvegicus
RET signaling Rattus norvegicus
Disease
Displaying all 6 entries
DO ID Disease Name Source
DOID:0050741 alcohol dependence
DOID:0080855 Parkinsonism
DOID:12700 hyperprolactinemia
DOID:1574 alcohol use disorder
DOID:3328 temporal lobe epilepsy
DOID:3525 middle cerebral artery infarction

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025