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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
gamma-aminobutyric acid type B receptor subunit 1
Summary
- Gene Symbol
-
- Gabbr1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Cell projection
- Coiled coil
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Phosphoprotein
- Postsynaptic cell membrane
- Reference proteome
- Repeat
- Signal
- Sushi
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of glutamate secretion | ||
| adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway | ||
| regulation of postsynaptic membrane potential | ||
| synaptic transmission, GABAergic | ||
| negative regulation of gamma-aminobutyric acid secretion |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Schaffer collateral - CA1 synapse | ||
| membrane | ||
| postsynaptic membrane | ||
| mitochondrial membrane | ||
| presynapse |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- gamma-aminobutyric acid type B receptor subunit 1
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| G protein-coupled GABA receptor activity |
| gamma-aminobutyric acid signaling pathway |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050741 | alcohol dependence | |
| DOID:0050742 | nicotine dependence | |
| DOID:10763 | hypertension | |
| DOID:11832 | visual epilepsy | |
| DOID:670 | amphetamine abuse | |
| DOID:9975 | cocaine dependence | |
| DOID:9976 | heroin dependence |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2550 | HGNC:4070 | HUMAN83621 | ||
| 34878 | FB:FBgn0260446 | |||
| 54393 | 10090_1:004cb9 | MGI:1860139 | MOUSE23129 | |
| 189837 | WB:WBGene00021528 | |||
| 373873 | ZFIN:ZDB-GENE-030904-5 | DANRE09084 | ||
| 471946 | PANTR37543 | |||
| 513785 | BOVIN18898 | |||
| 558708 | ZFIN:ZDB-GENE-060503-5 | DANRE16199 | ||
| 708987 | MACMU35172 | |||
| 100074873 | ORNAN32182 |
