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celiac disease
Summary
- Synonym
-
- celiac sprue
- coeliac disease
- idiopathic steatorrhea
- Definition
- An autoimmune disease of gastrointestinal tract that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite.
- Super Class
- autoimmune disease of gastrointestinal tract
External Links
- Disease Ontology
- DOID:10608
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- ORDO
- OMIM
- GARD
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 5293 | PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | |
| 5294 | PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | |
| 5321 | PLA2G4A | phospholipase A2 group IVA | |
| 5728 | PTEN | phosphatase and tensin homolog | |
| 6382 | SDC1 | syndecan 1 | |
| 6401 | SELE | selectin E | |
| 6402 | SELL | selectin L | |
| 8435 | SOAT2 | sterol O-acyltransferase 2 | |
| 8694 | DGAT1 | diacylglycerol O-acyltransferase 1 | |
| 8807 | IL18RAP | interleukin 18 receptor accessory protein |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9ULC5 | Long-chain-fatty-acid--CoA ligase 5 |
