age related macular degeneration

Summary
Synonym
  • Age Related Maculopathies
  • Age Related Maculopathy
  • Senile macular degeneration
  • Senile macular retinal degeneration
  • age-related macular degeneration
Definition
A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision.
Super Class
autosomal dominant disease degeneration of macula and posterior pole
Disease Ontology
DOID:10871
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying all 5 entries
Gene ID Gene Symbol Description Source
4179 CD46 CD46 molecule
6347 CCL2 C-C motif chemokine ligand 2
10516 FBLN5 fibulin 5
10891 PPARGC1A PPARG coactivator 1 alpha
729230 CCR2 C-C motif chemokine receptor 2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
17221 Cd46 CD46 antigen, complement regulatory protein
19017 Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
20296 Ccl2 C-C motif chemokine ligand 2
23876 Fbln5 fibulin 5
Displaying all 4 entries
Gene ID Gene Symbol Description Source
24770 Ccl2 C-C motif chemokine ligand 2
29158 Fbln5 fibulin 5
29333 Cd46 CD46 molecule
83516 Ppargc1a PPARG coactivator 1 alpha

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024