Membrane cofactor protein

Summary
UniProt ID
O88174
Gene Symbol
  • Cd46
  • Mcp
Gene ID
17221
Organism
Mus musculus (house mouse)
PubChem
O88174
Re-Glyco
O88174
Annotation
Keyword
  • Alternative splicing
  • Cytoplasmic vesicle
  • Disulfide bond
  • Fertilization
  • Glycoprotein
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Sushi
  • Transmembrane helix
Gene Ontology (GO)
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying 1 entry
GO Term
single fertilization
Sequence
MTAAPLMPDSTHPCRRRKSYTFFWCSLGVYAEALLFLLSHLSDACELPRPFEAMELKGTPKLFYAVGEKIEYKCKKGYLYLSPYLMIATCEPNHTWVPISDAGCIKVQCTMLQDPSFGKVYYIDGSFSWGARAKFTCMEGYYVVGMSVLHCVLKGDDEAYWNGYPPHCEKIYCLPPPKIKNGTHTLTDINVFKYHEAVSYSCDPTPGPDKFSLVGTSMIFCAGHNTWSNSPPECKVVKCPNPVLQNGRLISGAGEIFSYQSTVMFECLQGFYMEGSSMVICSANNSWEPSIPKCLKGPRPTHPTKPPVYNYTGYPSPREGIFSQELDAWIIALIVITSIVGVFILCLIVLRCFEHRKKTNVSAAR
Glycosylation Sites
Displaying all 6 entries
Position Description PubMed ID GlyTouCan ID Source
181 N-linked (GlcNAc...) asparagine
205 O-linked (GalNAc...) threonine
301 O-linked (GalNAc...) threonine
304 O-linked (GalNAc...) threonine
310 N-linked (GlcNAc...) asparagine
312 O-linked (GalNAc...) threonine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying 1 entry
Pathway Name Organism
Regulation of Complement cascade Mus musculus
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:10871 age related macular degeneration

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025