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sickle cell anemia
Summary
- Synonym
-
- Hb SC disease
- Hb-S/Hb-C disease
- Hb-SS disease without crisis
- Hemoglobin S disease without crisis
- Sickle-cell/Hb-C disease without crisis
- drepanocytosis
- haemoglobin SC disease
- hemoglobin SC disease
- sickle cell anaemia
- Definition
- A blood protein disease that is characterized by low number of red blood cells, repeated infections, and periodic episodes of pain, resulting from atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
- Super Class
- autosomal recessive disease blood protein disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3098 | HK1 | hexokinase 1 | |
| 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | |
| 4846 | NOS3 | nitric oxide synthase 3 | |
| 4879 | NPPB | natriuretic peptide B | |
| 5175 | PECAM1 | platelet and endothelial cell adhesion molecule 1 | |
| 5228 | PGF | placental growth factor | |
| 5444 | PON1 | paraoxonase 1 | |
| 6708 | SPTA1 | spectrin alpha, erythrocytic 1 | |
| 7040 | TGFB1 | transforming growth factor beta 1 | |
| 7124 | TNF | tumor necrosis factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 18613 | Pecam1 | platelet/endothelial cell adhesion molecule 1 | |
| 18654 | Pgf | placental growth factor | |
| 18979 | Pon1 | paraoxonase 1 | |
| 20739 | Spta1 | spectrin alpha, erythrocytic 1 | |
| 21803 | Tgfb1 | transforming growth factor, beta 1 | |
| 21926 | Tnf | tumor necrosis factor | |
| 21947 | Cd40lg | CD40 ligand | |
| 238055 | Apob | apolipoprotein B |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24232 | C3 | complement C3 | |
| 24600 | Nos3 | nitric oxide synthase 3 | |
| 24835 | Tnf | tumor necrosis factor | |
| 25058 | Hk1 | hexokinase 1 | |
| 29583 | Pecam1 | platelet and endothelial cell adhesion molecule 1 | |
| 54225 | Apob | apolipoprotein B | |
| 59086 | Tgfb1 | transforming growth factor, beta 1 | |
| 84024 | Pon1 | paraoxonase 1 | |
| 84349 | Cd40lg | CD40 ligand | |
| 94203 | Pgf | placental growth factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171999 | poml-2 | Arylesterase | |
| 176673 | scav-3 | Sensory neuron membrane protein 2 | |
| 176787 | scav-2 | SCAVenger receptor (CD36 family) related | |
| 181178 | gpx-5 | Glutathione peroxidase | |
| 182513 | gpx-3 | Glutathione peroxidase 3 | |
| 187297 | poml-1 | PON (paraoxonase) and MEC-6 Like |
