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Guidelines

MIRAGE

nitric oxide synthase 3

Summary

Gene Symbol

Nos3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24600

PubChem

24600

Alliance of Genome Resources

RGD:3186

Annotation

Keyword

Calcium
Calmodulin-binding
Cell membrane
Cytoskeleton
FAD
FMN
Golgi apparatus
Heme
Myristate
NADP
Oxidoreductase
Palmitate
Phosphoprotein
Reference proteome
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q62600	Constitutive NOS EC-NOS NOS type III Nitric oxide synthase, endothelial

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of **125** in total

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GO Term	Evidence Code	PMID
angiogenesis	ISO
angiogenesis	IEA
ovulation from ovarian follicle	ISO
ovulation from ovarian follicle	IEA
response to hypoxia	IEP	17947499

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

reactive nitrogen species metabolic process [inference]

nitric oxide metabolic process

nitric oxide biosynthetic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

removal of superoxide radicals

primary metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

lipopolysaccharide-mediated signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

nitric oxide mediated signal transduction

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid metabolic process [inference]

glutamine family amino acid metabolic process [inference]

arginine metabolic process [inference]

arginine catabolic process

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

alpha-amino acid catabolic process [inference]

glutamine family amino acid catabolic process [inference]

arginine catabolic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

nitric oxide biosynthetic process

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

removal of superoxide radicals

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

endothelial cell migration

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to magnesium ion

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to organic cyclic compound

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to ketone [inference]

cellular response to rotenone

cellular response to lipoprotein particle stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

cellular detoxification [inference]

cellular oxidant detoxification [inference]

removal of superoxide radicals

reproductive process [inference]

ovulation cycle process [inference]

ovulation from ovarian follicle

multi-organism reproductive process [inference]

female pregnancy

multicellular organismal reproductive process [inference]

ovulation [inference]

ovulation from ovarian follicle

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle adaptation [inference]

smooth muscle adaptation [inference]

smooth muscle hyperplasia

muscle hyperplasia [inference]

smooth muscle hyperplasia

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance

vasodilation

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by endothelin

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

multi-multicellular organism process [inference]

female pregnancy

tissue remodeling [inference]

blood vessel remodeling

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

homeostasis of number of cells within a tissue

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

developmental process [inference]

anatomical structure morphogenesis [inference]

heart valve morphogenesis [inference]

tissue morphogenesis [inference]

mesenchyme morphogenesis [inference]

endocardial cushion morphogenesis

cardiac septum morphogenesis [inference]

ventricular septum morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

animal organ development [inference]

retina development in camera-type eye

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

homeostasis of number of cells within a tissue

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

homeostasis of number of cells within a tissue

rhythmic process [inference]

ovulation cycle process [inference]

ovulation from ovarian follicle

response to stimulus [inference]

response to stress [inference]

response to hypoxia

response to heat [inference]

cellular response to heat

response to wounding [inference]

response to axon injury

cellular response to stress [inference]

cellular response to heat

response to external stimulus [inference]

response to mechanical stimulus

response to extracellular stimulus [inference]

response to nutrient levels

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat [inference]

cellular response to heat

response to mechanical stimulus

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to increased oxygen levels [inference]

response to hyperoxia

response to magnetism

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to endogenous stimulus [inference]

response to hormone

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

response to growth factor [inference]

cellular response to growth factor stimulus

cellular response to transforming growth factor beta stimulus

response to transforming growth factor beta [inference]

cellular response to transforming growth factor beta stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to growth factor stimulus

cellular response to transforming growth factor beta stimulus

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to activity

response to chemical [inference]

response to acid chemical [inference]

response to amino acid

response to L-arginine

response to xenobiotic stimulus

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide hormone

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

response to carbohydrate

response to monosaccharide [inference]

response to hexose [inference]

response to fructose

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

response to amino acid

response to L-arginine

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide

response to peptide hormone

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to organic cyclic compound

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

response to estradiol

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

cellular response to organic cyclic compound

response to rotenone [inference]

cellular response to rotenone

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid [inference]

response to corticosterone

response to mineralocorticoid [inference]

response to corticosterone

response to cytokine

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

response to erythropoietin

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

response to organophosphorus [inference]

response to cAMP [inference]

cellular response to cAMP

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to organic cyclic compound

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to alcohol [inference]

response to ketone

response to corticosterone

cellular response to ketone [inference]

cellular response to rotenone

response to rotenone [inference]

cellular response to rotenone

response to inorganic substance [inference]

response to metal ion

response to lead ion

response to magnesium ion [inference]

cellular response to magnesium ion

response to mercury ion

cellular response to metal ion [inference]

cellular response to magnesium ion

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to magnesium ion

response to nicotine

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to magnesium ion

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to organic cyclic compound

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to ketone [inference]

cellular response to rotenone

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to purine-containing compound [inference]

response to cAMP [inference]

cellular response to cAMP

response to amino acid

response to L-arginine

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to peptide

response to peptide hormone

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to oxygen-containing compound [inference]

response to carbohydrate

response to monosaccharide [inference]

response to hexose [inference]

response to fructose

response to amino acid

response to L-arginine

response to cAMP [inference]

cellular response to cAMP

response to alcohol [inference]

response to peptide

response to peptide hormone

response to insulin [inference]

cellular response to insulin stimulus

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

response to ketone

response to corticosterone

cellular response to ketone [inference]

cellular response to rotenone

response to rotenone [inference]

cellular response to rotenone

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to ketone [inference]

cellular response to rotenone

response to salt

muscle adaptation [inference]

smooth muscle adaptation [inference]

smooth muscle hyperplasia

muscle hyperplasia [inference]

smooth muscle hyperplasia

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to heat

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to magnesium ion

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to cytokine stimulus [inference]

cellular response to tumor necrosis factor

cellular response to organic cyclic compound

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to nitrogen compound [inference]

cellular response to organonitrogen compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to oxygen-containing compound [inference]

cellular response to cAMP

cellular response to peptide [inference]

cellular response to peptide hormone stimulus [inference]

cellular response to insulin stimulus

cellular response to ketone [inference]

cellular response to rotenone

cellular response to lipoprotein particle stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

organic substance transport [inference]

calcium ion transport

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of small molecule metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of small molecule metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of small molecule metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of sodium ion transport

regulation of potassium ion transport [inference]

negative regulation of potassium ion transport

regulation of calcium ion transport [inference]

negative regulation of calcium ion transport

negative regulation of monoatomic ion transport [inference]

negative regulation of transport [inference]

negative regulation of monoatomic ion transport [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of small molecule metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of smooth muscle cell proliferation

negative regulation of response to stimulus [inference]

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

negative regulation of transport [inference]

negative regulation of monoatomic ion transport [inference]

negative regulation of developmental process [inference]

negative regulation of biomineral tissue development

negative regulation of multicellular organismal process [inference]

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

regulation of response to stimulus [inference]

regulation of muscle adaptation [inference]

regulation of muscle hyperplasia [inference]

negative regulation of muscle hyperplasia

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

negative regulation of response to stimulus [inference]

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

negative regulation of developmental process [inference]

negative regulation of biomineral tissue development

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

negative regulation of biomineral tissue development

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

lipopolysaccharide-mediated signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

nitric oxide mediated signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of phosphate metabolic process [inference]

regulation of nucleotide metabolic process [inference]

regulation of nucleotide biosynthetic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of purine nucleotide metabolic process [inference]

regulation of purine nucleotide biosynthetic process [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of smooth muscle cell proliferation

regulation of smooth muscle cell proliferation [inference]

negative regulation of smooth muscle cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleotide metabolic process [inference]

positive regulation of nucleotide biosynthetic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of purine nucleotide metabolic process [inference]

positive regulation of purine nucleotide biosynthetic process [inference]

positive regulation of guanylate cyclase activity

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of smooth muscle cell proliferation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of system process [inference]

regulation of nervous system process

regulation of muscle system process [inference]

regulation of muscle adaptation [inference]

regulation of muscle hyperplasia [inference]

negative regulation of muscle hyperplasia

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of the force of heart contraction [inference]

regulation of the force of heart contraction by chemical signal

positive regulation of multicellular organismal process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of muscle adaptation [inference]

negative regulation of muscle hyperplasia

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

negative regulation of biomineral tissue development

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of biological quality [inference]

regulation of the force of heart contraction [inference]

regulation of the force of heart contraction by chemical signal

regulation of blood pressure [inference]

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by endothelin

negative regulation of blood pressure

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance

vasodilation

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of guanylate cyclase activity

regulation of catalytic activity [inference]

regulation of cyclase activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of guanylate cyclase activity

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of catalytic activity [inference]

positive regulation of cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of guanylate cyclase activity

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity

regulation of lyase activity [inference]

regulation of guanylate cyclase activity [inference]

positive regulation of guanylate cyclase activity

positive regulation of lyase activity [inference]

positive regulation of guanylate cyclase activity

detoxification [inference]

cellular detoxification [inference]

cellular oxidant detoxification [inference]

removal of superoxide radicals

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
nucleus	ISO
nucleus	IDA	11943139
nucleus	IBA
nucleus	IEA
cytoplasm	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

sarcolemma

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

apical part of cell

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GO Term	Evidence Code	PMID
actin binding	IDA	15858215
actin monomer binding	ISO
actin monomer binding	IEA
nitric-oxide synthase activity	ISO
nitric-oxide synthase activity	IDA	12388111

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

nitric-oxide synthase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

nitric-oxide synthase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin monomer binding

enzyme binding [inference]

nitric-oxide synthase binding

heat shock protein binding [inference]

Hsp90 protein binding

cell adhesion molecule binding [inference]

cadherin binding

scaffold protein binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

amino acid binding [inference]

arginine binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

ribonucleotide binding [inference]

FMN binding

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

FMN binding

carboxylic acid binding [inference]

amino acid binding [inference]

arginine binding

flavin adenine dinucleotide binding

cation binding [inference]

organic cyclic compound binding [inference]

tetrahydrobiopterin binding

tetrapyrrole binding [inference]

heme binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

ribonucleotide binding [inference]

FMN binding

flavin adenine dinucleotide binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

FMN binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

nitric oxide synthase, endothelial

Functional Category

C: Energy production and conversion
K: Transcription
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
FMN binding
NADP binding
calmodulin binding
flavin adenine dinucleotide binding
heme binding
metal ion binding
nitric oxide biosynthetic process
nitric-oxide synthase activity
oxidoreductase activity

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InterPro
FAD-binding domain, ferredoxin reductase-type
Ferredoxin-NADP reductase (FNR), nucleotide-binding domain
Flavodoxin-like
Flavodoxin/nitric oxide synthase
Flavoprotein pyridine nucleotide cytochrome reductase
Flavoprotein-like superfamily
NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily
Nitric oxide synthase, N-terminal domain superfamily
Nitric oxide synthase, N-terminal
Nitric oxide synthase, domain 1 superfamily

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
apical part of cell	PMID:17123860
sarcolemma	PMID:9111020
caveola	PMID:29217667

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0050852	limb ischemia	Alliance of Genome Resources
DOID:1073	renal hypertension	Alliance of Genome Resources
DOID:10762	portal hypertension	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:224	transient cerebral ischemia	Alliance of Genome Resources
DOID:2316	brain ischemia	Alliance of Genome Resources
DOID:5082	liver cirrhosis	Alliance of Genome Resources
DOID:5844	myocardial infarction	Alliance of Genome Resources
DOID:6432	pulmonary hypertension	Alliance of Genome Resources
DOID:8466	retinal degeneration	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	4842	FB:FBgn0011676
Drosophila melanogaster	4843	FB:FBgn0011676
Homo sapiens	4846	Xenbase:XB-GENE-480698	HUMAN92039
Mus musculus	18127	Xenbase:XB-GENE-480698	MOUSE45273
Drosophila melanogaster	24598	FB:FBgn0011676
Xenopus tropicalis	24600	Xenbase:XB-GENE-480698
Bos taurus	287024		BOVIN28740
Sus scrofa	397557		PIGXX12287
Canis lupus familiaris	403784		CANLF04581
Macaca mulatta	714231		MACMU33163

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: March 31, 2025