osteoporosis

Summary
Definition
A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.
Super Class
bone resorption disease
External Links
Disease Ontology
DOID:11476
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 81 - 90 of 128 in total
Gene ID Gene Symbol Description Source
5294 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
5315 PKM pyruvate kinase M1/2
5336 PLCG2 phospholipase C gamma 2
5373 PMM2 phosphomannomutase 2
5563 PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2
5728 PTEN phosphatase and tensin homolog
6484 ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
6609 SMPD1 sphingomyelin phosphodiesterase 1
6646 SOAT1 sterol O-acyltransferase 1
6718 AKR1D1 aldo-keto reductase family 1 member D1
Displaying all 7 entries
Gene ID Gene Symbol Description Source
16002 Igf2 insulin-like growth factor 2
16846 Lep leptin
16847 Lepr leptin receptor
16973 Lrp5 low density lipoprotein receptor-related protein 5
17869 Myc myelocytomatosis oncogene
18538 Pcna proliferating cell nuclear antigen
26416 Mapk14 mitogen-activated protein kinase 14
Displaying all 5 entries
Gene ID Gene Symbol Description Source
24483 Igf2 insulin-like growth factor 2
24536 Lepr leptin receptor
24577 Myc MYC proto-oncogene, bHLH transcription factor
25608 Lep leptin
25737 Pcna proliferating cell nuclear antigen
Related Glycoprotein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024