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Pick's disease
Summary
- Synonym
-
- Dementia in Pick's disease
- LOBAR ATROPHY OF BRAIN
- PICK DISEASE OF BRAIN
- Pick disease
- Definition
- A frontotemporal dementia that is characterized by a spectrum of neuropsychiatric symptoms ranging from those that affect the patient's personality to those that cause a decline in cognitive function.
- Super Class
- frontotemporal dementia
External Links
- Disease Ontology
- DOID:11870
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1385 | CREB1 | cAMP responsive element binding protein 1 | |
| 1386 | ATF2 | activating transcription factor 2 | |
| 2353 | FOS | Fos proto-oncogene, AP-1 transcription factor subunit | |
| 4137 | MAPT | microtubule associated protein tau | |
| 5608 | MAP2K6 | mitogen-activated protein kinase kinase 6 | |
| 6620 | SNCB | synuclein beta | |
| 6622 | SNCA | synuclein alpha | |
| 23435 | TARDBP | TAR DNA binding protein |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11909 | Atf2 | activating transcription factor 2 | |
| 14281 | Fos | FBJ osteosarcoma oncogene | |
| 17758 | Map4 | microtubule-associated protein 4 | |
| 17762 | Mapt | microtubule-associated protein tau | |
| 20617 | Snca | synuclein, alpha | |
| 104069 | Sncb | synuclein, beta | |
| 140483 | Hnmt | histamine N-methyltransferase |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000710 | Hyperorality |
| HP:0000718 | Aggressive behavior |
| HP:0000719 | Inappropriate behavior |
| HP:0000723 | Restrictive behavior |
| HP:0000733 | Motor stereotypy |
| HP:0000734 | Disinhibition |
| HP:0000737 | Irritability |
| HP:0000741 | Apathy |
| HP:0000757 | Lack of insight |
| HP:0001288 | Gait disturbance |
