microtubule associated protein tau

Summary
Gene Symbol
  • MAPT
Organism
Homo sapiens (human)
NCBI Gene
4137
PubChem
4137
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Alzheimer disease
  • Cell membrane
  • Cell projection
  • Cytoskeleton
  • Direct protein sequencing
  • Disease variant
  • Disulfide bond
  • Glycation
  • Isopeptide bond
  • Methylation
  • Microtubule
  • Neurodegeneration
  • Parkinsonism
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Secreted
  • Ubl conjugation
Proteins
Displaying all 2 entries
UniProt Protein Name
B3KTM0
P10636
  • Neurofibrillary tangle protein
  • Paired helical filament-tau
Gene Ontology (GO)
GO Hierarchy
Displaying entries 1 - 5 of 39 in total
GO Term Evidence Code PMID
extracellular region
nucleus
nucleus
cytoplasm
cytoplasm
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
microtubule-associated protein
Functional Category
  • C: Energy production and conversion
  • E: Amino acid transport and metabolism
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying all 9 entries
DO ID Disease Name Source
DOID:0060892 late onset Parkinson's disease
DOID:10652 Alzheimer's disease
DOID:11870 Pick's disease
DOID:1307 dementia
DOID:14330 Parkinson's disease
DOID:3328 temporal lobe epilepsy
DOID:678 progressive supranuclear palsy
DOID:680 tauopathy
DOID:9255 frontotemporal dementia

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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