progressive supranuclear palsy

Summary
Synonym
  • Steele-Richardson-Olszewski syndrome
  • progressive supranuclear ophthalmoplegia
Definition
A movement disease that is characterized by serious and progressive problems with control of gait and balance, along with complex eye movement and thinking problems. It involves gradual deterioration and death of specific volumes of the brain.
Super Class
movement disease
Disease Ontology
DOID:678
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
GARD
Related Genes
Displaying all 3 entries
Gene ID Gene Symbol Description Source
10 NAT2 N-acetyltransferase 2
4137 MAPT microtubule associated protein tau
5608 MAP2K6 mitogen-activated protein kinase kinase 6

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025