Chagas disease

Summary
Synonym
  • Chagas' disease
  • chagas' disease with digestive system involvement
  • chagas' disease with nervous system involvement
  • chagas' disease with other organ involvement
Definition
A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.
Super Class
trypanosomiasis
External Links
Disease Ontology
DOID:12140
Mondo Disease Ontology
MeSH
UMLS
ORDO
GARD
Related Genes
Displaying entries 1 - 10 of 35 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
43 ACHE acetylcholinesterase (Yt blood group)
142 PARP1 poly(ADP-ribose) polymerase 1
240 ALOX5 arachidonate 5-lipoxygenase
412 STS steroid sulfatase
811 CALR calreticulin
1555 CYP2B6 cytochrome P450 family 2 subfamily B member 6
1595 CYP51A1 cytochrome P450 family 51 subfamily A member 1
1636 ACE angiotensin I converting enzyme
2220 FCN2 ficolin 2

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024