Chagas disease

Summary
Synonym
  • Chagas' disease
  • chagas' disease with digestive system involvement
  • chagas' disease with nervous system involvement
  • chagas' disease with other organ involvement
Definition
A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.
Super Class
trypanosomiasis
Disease Ontology
DOID:12140
Mondo Disease Ontology
MeSH
UMLS
ORDO
GARD
Related Genes
Displaying all 4 entries
Gene ID Gene Symbol Description Source
1129 CHRM2 cholinergic receptor muscarinic 2
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3308 HSPA4 heat shock protein family A (Hsp70) member 4
6646 SOAT1 sterol O-acyltransferase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
25712 Ifng interferon gamma

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025