chronic closed-angle glaucoma

Summary
Synonym
  • Anatomical narrow angle glaucoma
  • chronic angle-closure glaucoma
  • chronic narrow angle glaucoma
Definition
A primary angle-closure glaucoma characterized by chronic and progressive narrowing of the anterior chamber angle by an intrinsic defect such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Chronic closed-angle glaucoma has_symptom progressive loss of peripheral vision, decreased vision, and occasionally headaches. Chronic closed-angle glaucoma can be caused by anatomically narrow angle, defects in the trabecular meshwork, and iris abnormalities. Primary angle-closure glaucoma has a strong genetic component.
Super Class
primary angle-closure glaucoma
External Links
Disease Ontology
DOID:14445
UMLS
Related Genes
Displaying all 9 entries
Gene ID Gene Symbol Description Source
847 CAT catalase
1103 CHAT choline O-acetyltransferase
1109 AKR1C4 aldo-keto reductase family 1 member C4
1545 CYP1B1 cytochrome P450 family 1 subfamily B member 1
1555 CYP2B6 cytochrome P450 family 2 subfamily B member 6
1634 DCN decorin
4907 NT5E 5'-nucleotidase ecto
4968 OGG1 8-oxoguanine DNA glycosylase
8818 DPM2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory
Related Glycoprotein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024