major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 121 - 130 of 217 in total
Gene ID Gene Symbol Description Source
5743 PTGS2 prostaglandin-endoperoxide synthase 2
6319 SCD stearoyl-CoA desaturase
6392 SDHD succinate dehydrogenase complex subunit D
6401 SELE selectin E
6403 SELP selectin P
6448 SGSH N-sulfoglucosamine sulfohydrolase
6476 SI sucrase-isomaltase
6484 ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
6487 ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
6517 SLC2A4 solute carrier family 2 member 4
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A

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Last updated: August 19, 2024