major depressive disorder

Summary
Synonym
  • clinical depression
  • major depression
  • recurrent major depression
  • single major depressive episode
  • unipolar depression
Definition
A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality.
Super Class
depressive disorder
External Links
Disease Ontology
DOID:1470
Mondo Disease Ontology
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 211 - 217 of 217 in total
Gene ID Gene Symbol Description Source
159371 SLC35G1 solute carrier family 35 member G1
165631 PARP15 poly(ADP-ribose) polymerase family member 15
166929 SGMS2 sphingomyelin synthase 2
257202 GPX6 glutathione peroxidase 6
266727 MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1
283871 PGP phosphoglycolate phosphatase
340075 ARSI arylsulfatase family member I
Displaying 1 entry
Gene ID Gene Symbol Description Source
15558 Htr2a 5-hydroxytryptamine (serotonin) receptor 2A
Displaying 1 entry
Gene ID Gene Symbol Description Source
29595 Htr2a 5-hydroxytryptamine receptor 2A

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024