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acute chest syndrome
Summary
- Synonym
-
- acute chest syndrome in sickle cell disease
- Definition
- A lung disease that involves a vasoocclusive crisis of the pulmonary vasculature seen in patients with sickle cell anemia. The crisis is initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion. The disease has_symptom fever, has_symptom pleuritic chest pain, has_symptom tachypnea, has_symptom cough, has_symptom hypoxemia, has_symptom marked leukocytosis, and has_symptom diffuse infiltrates on chest radiograph.
- Super Class
- lung disease
External Links
- Disease Ontology
- DOID:1584
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3897 | L1CAM | L1 cell adhesion molecule | |
| 3931 | LCAT | lecithin-cholesterol acyltransferase | |
| 3958 | LGALS3 | galectin 3 | |
| 3988 | LIPA | lipase A, lysosomal acid type | |
| 3992 | FADS1 | fatty acid desaturase 1 | |
| 4023 | LPL | lipoprotein lipase | |
| 4968 | OGG1 | 8-oxoguanine DNA glycosylase | |
| 4973 | OLR1 | oxidized low density lipoprotein receptor 1 | |
| 5130 | PCYT1A | phosphate cytidylyltransferase 1A, choline | |
| 5320 | PLA2G2A | phospholipase A2 group IIA |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9Y5X9 | Endothelial lipase |
