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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
multiple sclerosis
Summary
- Synonym
-
- Generalized multiple sclerosis
- insular sclerosis
- Definition
- A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
- Super Class
- autoimmune disease of central nervous system demyelinating disease
External Links
- Disease Ontology
- DOID:2377
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1312 | COMT | catechol-O-methyltransferase | |
| 1374 | CPT1A | carnitine palmitoyltransferase 1A | |
| 1463 | NCAN | neurocan | |
| 1545 | CYP1B1 | cytochrome P450 family 1 subfamily B member 1 | |
| 1555 | CYP2B6 | cytochrome P450 family 2 subfamily B member 6 | |
| 1557 | CYP2C19 | cytochrome P450 family 2 subfamily C member 19 | |
| 1559 | CYP2C9 | cytochrome P450 family 2 subfamily C member 9 | |
| 1576 | CYP3A4 | cytochrome P450 family 3 subfamily A member 4 | |
| 1581 | CYP7A1 | cytochrome P450 family 7 subfamily A member 1 | |
| 1586 | CYP17A1 | cytochrome P450 family 17 subfamily A member 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 16002 | Igf2 | insulin-like growth factor 2 | |
| 21898 | Tlr4 | toll-like receptor 4 | |
| 21926 | Tnf | tumor necrosis factor | |
| 56336 | B4galt5 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 | |
| 56386 | B4galt6 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 | |
| 100198 | H6pd | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 36585 | beta4GalNAcTA | beta1,4-N-acetylgalactosaminyltransferase A | |
| 43222 | Tl | Toll | |
| 43425 | beta4GalNAcTB | beta1,4-N-acetylgalactosaminyltransferase B |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 446703 | b4galt5.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog | Xenopus laevis (African clawed frog) | |
| 548965 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | Xenopus tropicalis (tropical clawed frog) | |
| 549139 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | Xenopus tropicalis (tropical clawed frog) | |
| 779435 | b4galt6.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog | Xenopus laevis (African clawed frog) | |
| 108695277 | b4galt6.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog | Xenopus laevis (African clawed frog) | |
| 108702589 | b4galt5.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog | Xenopus laevis (African clawed frog) |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P07585 | Decorin | |
| P07741 | Adenine phosphoribosyltransferase | |
| P07954 | Fumarate hydratase, mitochondrial | |
| P08571 | Monocyte differentiation antigen CD14 | |
| P08758 | Annexin A5 | |
| P09326 | CD48 antigen | |
| P09382 | Galectin-1 | |
| P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | |
| P09874 | Poly [ADP-ribose] polymerase 1 | |
| P10645 | Chromogranin-A |
