glioblastoma

Summary
Synonym
  • GBM
  • adult glioblastoma multiforme
  • glioblastoma multiforme
  • grade IV adult Astrocytic tumor
  • primary glioblastoma multiforme
  • spongioblastoma multiforme
Definition
A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
Super Class
malignant astrocytoma
External Links
Disease Ontology
DOID:3068
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 161 - 170 of 262 in total
Gene ID Gene Symbol Description Source
6519 SLC3A1 solute carrier family 3 member 1
6646 SOAT1 sterol O-acyltransferase 1
6900 CNTN2 contactin 2
7086 TKT transketolase
7108 TM7SF2 transmembrane 7 superfamily member 2
7157 TP53 tumor protein p53
7167 TPI1 triosephosphate isomerase 1
7357 UGCG UDP-glucose ceramide glucosyltransferase
7358 UGDH UDP-glucose 6-dehydrogenase
7360 UGP2 UDP-glucose pyrophosphorylase 2
Displaying all 5 entries
Gene ID Gene Symbol Description Source
12654 Chi3l1 chitinase 3 like 1
15926 Idh1 isocitrate dehydrogenase 1 (NADP+), soluble
18605 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
18654 Pgf placental growth factor
22059 Trp53 transformation related protein 53
Displaying all 5 entries
Gene ID Gene Symbol Description Source
24479 Idh1 isocitrate dehydrogenase (NADP(+)) 1
24842 Tp53 tumor protein p53
85496 Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1
89824 Chi3l1 chitinase 3 like 1
94203 Pgf placental growth factor
Displaying all 6 entries
Gene ID Gene Symbol Description Source
31926 Idgf4 Imaginal disc growth factor 4
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
Displaying 1 entry
Gene ID Gene Symbol Description Source
180628 cht-1 putative endochitinase
Displaying all 4 entries
Gene ID Gene Symbol Description Source
850871 IDP2 isocitrate dehydrogenase (NADP(+)) IDP2
851493 IDP1 isocitrate dehydrogenase (NADP(+)) IDP1
851977 CTS2 putative chitinase
855723 IDP3 isocitrate dehydrogenase (NADP(+)) IDP3

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024