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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Leigh disease
Summary
- Synonym
-
- Infantile necrotizing encephalomyelopathy
- Leigh syndrome
- juvenile subacute necrotizing encephalomyelopathy
- Definition
- A cytochrome-c oxidase deficiency disease characterized by progressive loss of mental and movement abilities. Symptoms usually begin between ages of three months and two years and include loss of appetite, vomiting, irritability and seizure activity.
- Super Class
- cytochrome-c oxidase deficiency disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1738 | DLD | dihydrolipoamide dehydrogenase | |
| 1890 | TYMP | thymidine phosphorylase | |
| 1892 | ECHS1 | enoyl-CoA hydratase, short chain 1 | |
| 4360 | MRC1 | mannose receptor C-type 1 | |
| 4967 | OGDH | oxoglutarate dehydrogenase | |
| 5160 | PDHA1 | pyruvate dehydrogenase E1 subunit alpha 1 | |
| 5162 | PDHB | pyruvate dehydrogenase E1 subunit beta | |
| 5226 | PGD | phosphogluconate dehydrogenase | |
| 5742 | PTGS1 | prostaglandin-endoperoxide synthase 1 | |
| 6389 | SDHA | succinate dehydrogenase complex flavoprotein subunit A |
Related Glycoprotein
