human immunodeficiency virus infectious disease

Summary
Synonym
  • HIV infection
Definition
A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
Super Class
viral infectious disease
Disease Ontology
DOID:526
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 31 in total
Gene ID Gene Symbol Description Source
355 FAS Fas cell surface death receptor
959 CD40LG CD40 ligand
1234 CCR5 C-C motif chemokine receptor 5
1555 CYP2B6 cytochrome P450 family 2 subfamily B member 6
2214 FCGR3A Fc gamma receptor IIIa
2638 GC GC vitamin D binding protein
3106 HLA-B major histocompatibility complex, class I, B
3107 HLA-C major histocompatibility complex, class I, C
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1

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