human immunodeficiency virus infectious disease

Summary
Synonym
  • HIV infection
Definition
A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 or has_material_basis_in Human immunodeficiency virus 2, which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands.
Super Class
viral infectious disease
Disease Ontology
DOID:526
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
WikiPathways (from TogoID)
Related Genes
Displaying entries 11 - 20 of 31 in total
Gene ID Gene Symbol Description Source
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3458 IFNG interferon gamma
3577 CXCR1 C-X-C motif chemokine receptor 1
3586 IL10 interleukin 10
3811 KIR3DL1 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
3813 KIR3DS1 killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1
4153 MBL2 mannose binding lectin 2
4288 MKI67 marker of proliferation Ki-67
4741 NEFM neurofilament medium chain
5243 ABCB1 ATP binding cassette subfamily B member 1

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