progressive multifocal leukoencephalopathy

Summary
Definition
A viral infectious disease that involves reactivation of JC polyomavirus in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma.
Super Class
viral infectious disease
Disease Ontology
DOID:643
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying 1 entry
Gene ID Gene Symbol Description Source
4747 NEFL neurofilament light chain
Displaying 1 entry
Gene ID Gene Symbol Description Source
18039 Nefl neurofilament, light polypeptide
Displaying 1 entry
Gene ID Gene Symbol Description Source
83613 Nefl neurofilament light chain

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.1.0

Last updated: December 9, 2024