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lupus erythematosus
Summary
- Synonym
-
- lupus
- Definition
- An autoimmune disease that is characterized by a constellation of findings that include elevated antibodies to nuclear antigens, antiphospholipids, low complement levels, ulcers, non-scarring alopecia, renal or neurologic damage, and low white blood cell and platelet counts, has_symptom rashes, fatigue, arthritis, hair loss, seizures, and symptoms related to affected organs.
- Super Class
- autoimmune disease of musculoskeletal system
External Links
- Disease Ontology
- DOID:8857
- Mondo Disease Ontology
- UMLS
- NCI Thesaurus
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 5091 | PC | pyruvate carboxylase | |
| 5230 | PGK1 | phosphoglycerate kinase 1 | |
| 5290 | PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | |
| 5291 | PIK3CB | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | |
| 5293 | PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | |
| 5294 | PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | |
| 5552 | SRGN | serglycin | |
| 5648 | MASP1 | MBL associated serine protease 1 | |
| 5742 | PTGS1 | prostaglandin-endoperoxide synthase 1 | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | |
| O43921 | Ephrin-A2 | |
| O75015 | Low affinity immunoglobulin gamma Fc region receptor III-B | |
| P00491 | Purine nucleoside phosphorylase | |
| P00558 | Phosphoglycerate kinase 1 | |
| P04040 | Catalase | |
| P04798 | Cytochrome P450 1A1 | |
| P05362 | Intercellular adhesion molecule 1 | |
| P06744 | Glucose-6-phosphate isomerase | |
| P07911 | Uromodulin |
