bronchiectasis

Summary
Synonym
  • Polynesian bronchiectasis
Definition
A bronchial disease that is a chronic inflammatory condition of one or more bronchi or bronchioles marked by dilatation and loss of elasticity of the walls resulting from damage to the airway wall leading to the formation of small sacs on the bronchial wall and impairment of cilia mobility in the lung. Inflammation of the bronchial wall increases mucus secretion which serves as a breeding ground for bacteria. Bronchiectasis is caused by repeated respiratory infections, immune deficiency disorders, hereditary disorders (cystic fibrosis or primary ciliary dyskinesia), mechanical factors (inhaled object or a lung tumor) or inhaling toxic substances.
Super Class
bronchial disease
External Links
Disease Ontology
DOID:9563
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
Related Genes
Displaying entries 1 - 10 of 20 in total
Gene ID Gene Symbol Description Source
811 CALR calreticulin
1056 CEL carboxyl ester lipase
2220 FCN2 ficolin 2
3383 ICAM1 intercellular adhesion molecule 1
3965 LGALS9 galectin 9
4153 MBL2 mannose binding lectin 2
5238 PGM3 phosphoglucomutase 3
5293 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
6440 SFTPC surfactant protein C
6441 SFTPD surfactant protein D
Displaying 1 entry
Gene ID Gene Symbol Description Source
21926 Tnf tumor necrosis factor
Displaying 1 entry
Gene ID Gene Symbol Description Source
24835 Tnf tumor necrosis factor

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024