bronchiectasis

Summary
Synonym
  • Polynesian bronchiectasis
Definition
A bronchial disease that is a chronic inflammatory condition of one or more bronchi or bronchioles marked by dilatation and loss of elasticity of the walls resulting from damage to the airway wall leading to the formation of small sacs on the bronchial wall and impairment of cilia mobility in the lung. Inflammation of the bronchial wall increases mucus secretion which serves as a breeding ground for bacteria. Bronchiectasis is caused by repeated respiratory infections, immune deficiency disorders, hereditary disorders (cystic fibrosis or primary ciliary dyskinesia), mechanical factors (inhaled object or a lung tumor) or inhaling toxic substances.
Super Class
bronchial disease
Disease Ontology
DOID:9563
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
Related Genes
Displaying all 5 entries
Gene ID Gene Symbol Description Source
1080 CFTR CF transmembrane conductance regulator
4153 MBL2 mannose binding lectin 2
4318 MMP9 matrix metallopeptidase 9
6890 TAP1 transporter 1, ATP binding cassette subfamily B member
7124 TNF tumor necrosis factor
Displaying all 4 entries
Gene ID Gene Symbol Description Source
12638 Cftr cystic fibrosis transmembrane conductance regulator
17195 Mbl2 mannose-binding lectin (protein C) 2
17395 Mmp9 matrix metallopeptidase 9
21926 Tnf tumor necrosis factor
Displaying all 3 entries
Gene ID Gene Symbol Description Source
24255 Cftr CF transmembrane conductance regulator
24835 Tnf tumor necrosis factor
81687 Mmp9 matrix metallopeptidase 9
Displaying 1 entry
Gene ID Gene Symbol Description Source
559080 cftr CF transmembrane conductance regulator
Displaying all 2 entries
Gene ID Gene Symbol Description Source
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
Displaying 1 entry
Gene ID Gene Symbol Description Source
853978 NFT1 putative multidrug transporter NFT1

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Acknowledgements

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Last updated: December 9, 2024