bronchiectasis

Summary
Synonym
  • Polynesian bronchiectasis
Definition
A bronchial disease that is a chronic inflammatory condition of one or more bronchi or bronchioles marked by dilatation and loss of elasticity of the walls resulting from damage to the airway wall leading to the formation of small sacs on the bronchial wall and impairment of cilia mobility in the lung. Inflammation of the bronchial wall increases mucus secretion which serves as a breeding ground for bacteria. Bronchiectasis is caused by repeated respiratory infections, immune deficiency disorders, hereditary disorders (cystic fibrosis or primary ciliary dyskinesia), mechanical factors (inhaled object or a lung tumor) or inhaling toxic substances.
Super Class
bronchial disease
Disease Ontology
DOID:9563
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
Related Genes
Displaying all 2 entries
Gene ID Gene Symbol Description Source
1080 CFTR CF transmembrane conductance regulator
6890 TAP1 transporter 1, ATP binding cassette subfamily B member

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025