obesity

Summary
Definition
An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness.
Super Class
overnutrition
Related Genes
Displaying entries 311 - 320 of 333 in total
Gene ID Gene Symbol Description Source
89858 SIGLEC12 sialic acid binding Ig like lectin 12
120227 CYP2R1 cytochrome P450 family 2 subfamily R member 1
123099 DEGS2 delta 4-desaturase, sphingolipid 2
126129 CPT1C carnitine palmitoyltransferase 1C
132789 GNPDA2 glucosamine-6-phosphate deaminase 2
138050 HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
140733 MACROD2 mono-ADP ribosylhydrolase 2
145264 SERPINA12 serpin family A member 12
148738 HJV hemojuvelin BMP co-receptor
151056 PLB1 phospholipase B1
Displaying entries 31 - 36 of 36 in total
Gene ID Gene Symbol Description Source
59027 Nampt nicotinamide phosphoribosyltransferase
68054 Serpina12 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
72774 Neil1 nei endonuclease VIII-like 1 (E. coli)
103988 Gck glucokinase
105787 Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit
230796 Wdtc1 WD and tetratricopeptide repeats 1
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
24267 Comt catechol-O-methyltransferase
24377 G6pd glucose-6-phosphate dehydrogenase
24383 Gapdh glyceraldehyde-3-phosphate dehydrogenase
24385 Gck glucokinase
24536 Lepr leptin receptor
24577 Myc MYC proto-oncogene, bHLH transcription factor
24835 Tnf tumor necrosis factor
25058 Hk1 hexokinase 1
25059 Hk2 hexokinase 2
25233 Akt2 AKT serine/threonine kinase 2
Displaying entry 11 - 11 of 11 in total
Gene ID Gene Symbol Description Source
117364 Hex-t1 Hexokinase testis 1
Displaying 1 entry
Gene ID Gene Symbol Description Source
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
Displaying all 4 entries
Gene ID Gene Symbol Description Source
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
178046 gspd-1 Glucose-6-phosphate 1-dehydrogenase
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
Displaying entries 1 - 10 of 11 in total
Gene ID Gene Symbol Description Source
850317 GLK1 glucokinase
850614 HXK1 hexokinase 1
851974 YPR1 trifunctional aldehyde reductase/carbonyl reductase (NADPH)/glucose 1-dehydrogenase (NADP(+)) YPR1
852128 EMI2 putative glucokinase
852639 HXK2 hexokinase 2
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
854287 GCY1 glycerol 2-dehydrogenase (NADP(+)) GCY1
855480 ZWF1 glucose-6-phosphate dehydrogenase
The Human Phenotype Ontology
Displaying all 5 entries
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0001513 Obesity
HP:0000006 Autosomal dominant inheritance
HP:0010982 Polygenic inheritance
HP:0012340 Decreased resting energy expenditure
Displaying all 2 entries
Gene ID Gene Symbol Description
9672 SDC3 syndecan 3
5167 ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1

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Last updated: August 19, 2024